

Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Sarah Ann Macklin
Health shouldn’t feel this hard.
I’ve lived it, studied it, and now I’m here to help make it make sense.
A smarter, more human way to live well.
Subscribe now, and start living well, for real.
Instagram: @sarahannmacklin
Newsletter: https://substack.com/@sarahannmacklin
Website: sarahannmacklin.com
#LiveWellBeWell
I’ve lived it, studied it, and now I’m here to help make it make sense.
A smarter, more human way to live well.
Subscribe now, and start living well, for real.
Instagram: @sarahannmacklin
Newsletter: https://substack.com/@sarahannmacklin
Website: sarahannmacklin.com
#LiveWellBeWell
Episodes
Mentioned books

Jan 28, 2026 • 1h 35min
Why Women Feel Like TWO DIFFERENT PEOPLE Every Month (The Science of Hormones) | Dr. Sarah Hill
Dr. Sarah Hill, evolutionary psychologist and author of This Is Your Brain on Birth Control and The Period Brain, explains how fluctuating estrogen, progesterone, and testosterone create distinct weekly mindsets. She discusses the “two advisors” view of the cycle, progesterone’s neuroprotective role, why symptoms vary with stress and sleep, and how hormones shape attraction, relationships, and decision-making.

Jan 26, 2026 • 7min
Is Your Phone Killing Your Creativity? 3 Ways to Boost Brain Health | Tj Power
Tj Power, speaker on brain health and creativity, shares simple habits to restore focus. He talks about boredom as daydreaming, the default mode and executive networks, and screen-free rules like no phones at meals/bed/ bathroom. Nature, stillness, and reduced task switching come up as ways to boost creativity and calm.

Jan 22, 2026 • 4min
Longevity Doctor: Alzheimer’s Is Preventable If You Do These 5 Things Early | Dr Darshan Shah
Dr. Darshan Shah, a longevity and Alzheimer’s expert, dives into preventative strategies against Alzheimer’s. He emphasizes the importance of testing for metabolic, inflammatory, and toxic drivers to personalize healthcare. Shah promotes lifestyle changes, including meditation and brain rest, to enhance cognitive health. He also discusses reducing home toxins through air purifiers, filtered water, and organic foods. Simple daily habits, rather than drastic overhauls, are key to lowering Alzheimer’s risk.

Jan 21, 2026 • 1h 21min
We Weren't Designed to be Happy: The Scientific Reason You Feel "Off" | Anders Hansen
This week, Anders Hansen, a psychiatrist and bestselling author, shares insights on how our brains are wired for survival, not perpetual happiness. He discusses how modern life exacerbates anxiety and alters our mental health, highlighting the importance of movement and connection. Anders explains that boredom can spark creativity, and he emphasizes the evolutionary roots of feelings like low self-esteem. The conversation also touches on how understanding our evolutionary past can foster self-compassion and guide us toward healthier experiences.

Jan 19, 2026 • 7min
Why Women Face Higher Alzheimer’s Risk (And The One Thing That Lowers It) | Dr Tommy Wood
Dr. Tommy Wood, a researcher focused on brain health, explores the striking fact that two-thirds of Alzheimer’s patients are women. He highlights how societal roles and lack of mental stimulation may worsen cognitive decline. Tommy discusses improvements in nutrition and heart health contributing to decreased dementia risk over the years. He emphasizes the protective benefits of complex environments—like engaging jobs and education—in maintaining cognition into older age. His insights suggest that changing women’s societal roles may positively impact dementia outcomes.

Jan 16, 2026 • 6min
The Brain Has Bacteria? What the Brain Microbiome Means for Health and Longevity | William Li
In this engaging discussion, Dr. William Li, a physician and researcher renowned for his work on beneficial microbes, reveals astonishing insights about the brain microbiome. He explains how once-thought-sterile areas, like the brain and breast milk, host helpful bacteria. The conversation dives into gut-brain communication through the vagus nerve and the importance of seeing bacteria as mostly beneficial rather than harmful. Li emphasizes the need for humility in medicine, urging listeners to tune into their bodies and adopt biohacking strategies for better health.

Jan 14, 2026 • 24min
The Hardest Thing I’ve Learned About Self-Talk — and How to Stop Beating Yourself Up
Explore the importance of listening to our bodies and recognizing early stress signals to enhance overall well-being. Discover how self-awareness can be a powerful tool in managing health and why compassion towards oneself is crucial for sustainable change. Learn about the impact of social media on inflammation and mental health, and the significance of creating phone-free spaces to foster emotional clarity. Ultimately, redefine success with a gentle approach to self-care and embrace the journey of aging gracefully.

Jan 12, 2026 • 6min
The Three S Model: Stimulus, Supply and Support for Cognitive Health and Dementia Risk | Dr Tommy Wood
In this engaging discussion, Dr. Tommy Wood, a physician and brain health researcher, delves into his innovative Three S model—stimulus, supply, and support—crucial for cognitive function. He emphasizes cognitive challenges as the primary stimulus for brain adaptation. The conversation explores the significance of key nutrients like omega-3s, B vitamins, and vitamin D in reducing dementia risk while highlighting the vital roles of blood flow and sleep for overall support. Discover how chronic stress and nutrient deficiencies can impact brain health!

Jan 9, 2026 • 5min
Human Performance Scientist: Are GLP-1 weight loss drugs a solution or a risk? | Andy Galpin
In this discussion, guest Andy Galpin, a human performance scientist specializing in metabolism, tackles the pros and cons of GLP-1 weight loss drugs. He shares insights on their effectiveness and the importance of understanding potential side effects like muscle loss. Andy emphasizes that while GLP-1 drugs could revolutionize weight loss, they shouldn’t be seen as a standalone solution. He advocates for a holistic approach, combining medication with nutrition education and strength training to achieve lasting health benefits.

Jan 7, 2026 • 1h 8min
Akkermansia, Cancer & GLP-1: How Your Gut Microbiome Shapes Immunity & the Brain | Dr William Li
Dr. William Li, a physician-scientist and president of the Angiogenesis Foundation, dives into the profound connection between our gut microbiome and overall health. He discusses groundbreaking insights on how specific gut bacteria like Akkermansia can enhance immunity, influence metabolism, and even impact cancer treatment responses. Li emphasizes the importance of nutrition, linking everyday foods to brain health, and highlights the role of social connections in longevity. He also shares practical advice on beverages and hydration to nurture our bodies effectively.


