

Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Sarah Ann Macklin
Health shouldn’t feel this hard.
I’ve lived it, studied it, and now I’m here to help make it make sense.
A smarter, more human way to live well.
Subscribe now, and start living well, for real.
Instagram: @sarahannmacklin
Newsletter: https://substack.com/@sarahannmacklin
Website: sarahannmacklin.com
#LiveWellBeWell
I’ve lived it, studied it, and now I’m here to help make it make sense.
A smarter, more human way to live well.
Subscribe now, and start living well, for real.
Instagram: @sarahannmacklin
Newsletter: https://substack.com/@sarahannmacklin
Website: sarahannmacklin.com
#LiveWellBeWell
Episodes
Mentioned books

Feb 20, 2026 • 9min
The #1 Science-Based Way To Improve Focus Starting Today | Anders Hansen
Anders Hansen, physician and bestselling author on brain health, shares science-backed ways to protect attention. He explains why our brains crave distraction. He highlights practical habits like phone removal and short bursts of movement. He outlines how exercise boosts brain blood flow, creativity, and memory and suggests simple, regular routines to make movement stick.

Feb 18, 2026 • 40min
The Nutrition Advice Making You Less Healthy: Four Signs To Watch | Nutritionist Sarah Ann Macklin
A warm solo conversation about why nutrition feels overwhelming and how to tune out noisy advice. She lays out four warning signs your eating habits are backfiring, from unstable energy and stress-driven choices to distracted meals and harsh self-talk. Practical ideas focus on stabilizing energy, calming the nervous system, and building simple systems that carry you through low-energy days.

Feb 16, 2026 • 7min
Alain De Botton: How Do You Heal a Broken Heart? The Importance of Closure & Self-Compassion
Alain de Botton, philosopher and author who makes ideas about everyday life accessible. He explores heartbreak as prolonged trauma, the damage of unexplained breakups, and why pain does not always lead to growth. He also discusses the slow shift toward self-compassion and the need for real closure to rebuild trust and identity.

Feb 13, 2026 • 7min
Estrogen vs. Progesterone: Why Women Need Both for Brain Protection | Sarah Hill
Sarah Hill, a research scientist who studies hormones and brain function, explains why both estrogen and progesterone matter. She unpacks the overlooked luteal phase. She highlights progesterone’s role in mood, sleep, decision making, and brain protection after injury. She raises questions about progesterone and Alzheimer’s.

Feb 11, 2026 • 1h 20min
Why You Still Can’t Orgasm (The Step-By-Step Guide) | Dr. Laurie Mintz, Sex Therapist
Dr. Laurie Mintz, licensed psychologist and sex therapist who studies women's sexuality and orgasm equality. She unpacks why clitoral stimulation matters, why culture and language created the orgasm gap, and how masturbation, vibrators, and clear communication can reshape pleasure. Short, direct, and myth-busting conversation that centers presence, anatomy, and reclaiming sexual agency.

Feb 9, 2026 • 4min
Why do healthy people still get Alzheimer’s disease? | Dr Darshan Shah
Dr Darshan Shah, a medical expert on Alzheimer’s risk, explains why disease can strike despite healthy habits. He highlights environmental toxins, metabolic markers like A1C, and hormone shifts in menopause. Short, clear takes on estrogen, IGF-1, thyroid changes, and genetic or detox resilience are discussed.

Feb 6, 2026 • 10min
This One Gut Microbe Could Decide If Cancer Treatment Works | William Li
William Li, physician-scientist known for gut microbiome and metabolism research, talks about Akkermansia muciniphila and its surprising roles. He covers how this keystone microbe links to insulin sensitivity, GLP-1 release, vascular and brain effects. He also explores associations between Akkermansia and cancer immunotherapy response, plus clinical implications for patient care.

25 snips
Feb 4, 2026 • 1h 41min
Why Compatibility is Overrated: Alain de Botton’s Guide to Relationships That Last
Alain de Botton, philosopher and founder of The School of Life, offers sharp reflections on love, vulnerability, and why lasting relationships are earned not found. He explores when to be open or guarded, how admitting folly builds resilience, why compatibility is overrated, and practical ways to handle heartbreak, criticism, and attachment patterns.

Feb 2, 2026 • 11min
How much social connection do we actually need? Loneliness, stress, and midlife health | Anders Hansen
Anders Hansen, psychiatrist and bestselling author who writes on brain health, explores social connection limits and loneliness. He discusses Dunbar's 150-relationship idea. He explains why in-person cues outperform screens, how brief calls can ease loneliness, and why AI companions and hyper-independence may backfire.

Jan 30, 2026 • 7min
Can gut bacteria influence brain disease? The microbiome, Parkinson’s and dementia | William Li
William Li, physician-researcher exploring biology and health. He discusses whether specific gut and mouth bacteria can affect brain health. Short segments cover Lactobacillus plantarum PS128 and Parkinson’s, links between gum disease and dementia, and Lactobacillus reuteri’s ties to oxytocin and social brain function.


