Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition

Why Women Feel Like TWO DIFFERENT PEOPLE Every Month (The Science of Hormones) | Dr. Sarah Hill

Jan 28, 2026
Dr. Sarah Hill, evolutionary psychologist and author of This Is Your Brain on Birth Control and The Period Brain, explains how fluctuating estrogen, progesterone, and testosterone create distinct weekly mindsets. She discusses the “two advisors” view of the cycle, progesterone’s neuroprotective role, why symptoms vary with stress and sleep, and how hormones shape attraction, relationships, and decision-making.
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INSIGHT

Two Wise Advisors

  • Hormones act as "two wise advisors" that shift brain states across the month.
  • Recognizing both phases improves decision-making by giving complementary perspectives.
INSIGHT

Progesterone Is Brain Protection

  • Progesterone is neuroprotective and slows brain firing to prevent excitotoxicity.
  • Its effects explain luteal-phase tiredness and emotional sensitivity as purposeful brain slowing.
ADVICE

Track Your Cycle To Regain Agency

  • Track your cycle to distinguish hormonal effects from life stressors and gain agency.
  • Use that awareness to plan work, rest, and communication around predictable shifts.
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