The Human Upgrade: Biohacking for Longevity & Performance

How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098

8 snips
Oct 18, 2023
Dr. Adeel Khan, a pioneer in gene and cell therapies, shares insights from his extensive work in regenerative medicine. He discusses his recent gene therapy experience, which promises to reduce biological age significantly. The conversation explores the evolution and impact of gene therapy on longevity, challenges in medical education, and the intersection of fitness and regenerative health. Khan also addresses personal autonomy in health choices, advancements like E. coli-derived mini circles, and the exciting potential of stem cell treatments for various health issues.
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ANECDOTE

Plasmid Gene Therapy

  • Early gene therapy used viral vectors, which posed safety risks and high costs.
  • Plasmid gene therapy, using a circular DNA strand from E. coli, offers a safer and more scalable approach.
ANECDOTE

Plasmids as Trading Cards

  • Bacteria use plasmids to share genetic information, like antibiotic resistance.
  • Dave Asprey likens plasmids to 'trading cards' for abilities, explaining how antibiotic resistance spreads.
INSIGHT

Follistatin's Anti-Aging Role

  • Follistatin, a peptide, is crucial for anti-aging by reducing inflammation and preserving muscle.
  • It inhibits myostatin, a protein that limits muscle growth, benefiting athletes and preventing age-related muscle loss.
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