LONGEVITY with Nathalie Niddam

Courtney Van Bussum, a biomedical engineer and longevity entrepreneur, explains NAD biology and why precursors or IVs can fail without system support. Short segments cover NAD/NADH balance, enzymes like CD38 and NNMT, methylation costs, and how 1-MNA can help. They also discuss when NAD infusions are useful, measuring NAD strain, and lifestyle and ketone strategies for cellular resilience.

Dr. Cynthia Keller, a pediatrician turned integrative-functional clinician who founded Centered in Wellness, discusses post-COVID nutrient depletion and its effects on mood, energy, and unexpected weight gain. She explains patterns like tryptophan and cofactor loss, gut and microbiome disruption, practical symptom-based nutrient trials, and why longer visits, listening, and family-wide approaches speed recovery.

Cathy Eason, nitric oxide and vascular health expert focused on midlife women, explains why falling estrogen in menopause harms blood flow and resilience. She highlights subtle signs like fatigue and brain fog. Short, actionable talks cover tracking vitals, wearables as feedback, diet, and a daily nitric oxide–support approach to protect heart and cognitive function.

Erin Ryan, podcast producer and health-space collaborator, co-hosts this audience Q&A. They tackle natural versus synthetic bioregulators, how short peptides survive digestion, and oral peptide quality risks. Conversation also covers organ versus system targeting, sourcing concerns, cycling and dosing strategies, and who benefits most from bioregulator use.

Dr. Regina Druz, a cardiologist who moved from elite academic medicine to integrative, preventive care and founder of Holistic Heart Centers. She discusses personalized genetics, hidden vascular risk in fit people, menopause and epicardial fat, and how wearables, AI, and stress shape heart-brain health. Short, practical prevention approaches and why screening earlier matters are highlighted.

Dr. Clement Lee, naturopathic doctor blending Chinese medicine with regenerative therapies and specialist in mold, toxins, and complex chronic illness. He explores how limbic system stress and nervous-system dysregulation precede lab findings. Topics include mold and toxic burden, inflammation loops, testing for heavy metals and mycotoxins, prolotherapy and neurotherapy, and regenerative tools like peptides, IVs, and filtration.

Dr. Jordan Plews, a biochemical engineer and stem cell researcher translating regenerative medicine into topical products. Debbi Barber, founder of Vitali Skincare and champion of clinical-strength copper peptides. They explore exosomes vs copper peptides, why source and dosing matter, how exosomes penetrate and signal deeper repair, safety and manufacturing standards, and practical layering for visible skin benefits.

Dr. Stephen Hussey, clinician and author who survived a premature widowmaker heart attack, explores alternative models of heart function and lifestyle approaches. He discusses structured water and blood flow, the heart as a vortex not just a pump, sunlight, grounding and circadian alignment, EMF effects, and practical steps he used to heal and rethink cardiovascular health.

Dr. Shivani Gupta, an Ayurvedic doctor and turmeric researcher, blends ancient wisdom with modern science. She explores turmeric versus NSAIDs, gut microbiome benefits, and curcumin absorption strategies. She also discusses inflammation as a root cause, circadian sleep rituals for recovery, elemental dosha-guided personalization, and simple stress-resilience practices.

Dr. Jeffrey Gladden, an interventional cardiologist turned longevity and age-management physician who now focuses on personalized medicine and psycho-spiritual health. He discusses reclaiming vitality through targeted testing and individualized treatments. Topics include mindset shifts for lifelong youth, five domains of exponential health, insulin resistance and metabolic testing, meditation and internal environment, and safe hormone and advanced therapy preparation.