The a16z Show
Andreessen Horowitz
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Episodes
Mentioned books
263 snips
Feb 5, 2026 • 29min
Why This Isn't the Dot-Com Bubble | Martin Casado on WSJ's BOLD NAMES
Martin Casado, general partner at Andreessen Horowitz with deep networking and cloud infrastructure expertise, explains why today's AI spending is different from the dot‑com era. He breaks down where AI dollars flow into data‑center infrastructure. He outlines infrastructure investing from chips to developer tools. He highlights the long tail of AI opportunities beyond the largest models.
213 snips
Feb 4, 2026 • 42min
Why America’s Health Crisis Is an Incentive Problem
Justin Mares, founder and CEO of TrueMed and entrepreneur focused on food and lifestyle interventions, discusses how US food policy and modern environments drive poor health. He covers crop subsidies, grocery-as-healthcare ideas, using HSA/FSA dollars for prevention, psychedelics and peptides as therapies, and treating chronic disease as a national security issue.
599 snips
Feb 3, 2026 • 1h 2min
Palmer Luckey on Hardware, Building, and the Next Frontiers of Innovation
Palmer Luckey, founder of Oculus VR and Anduril, is a builder of hardware and defense tech. He talks about making hardware at scale, VR display and tracking challenges, building many small product teams, AI and manufacturing frontiers, U.S.–China tech rivalry, and why optimism about fusion, quantum, and production still matters.
405 snips
Feb 2, 2026 • 37min
David Solomon & Ben Horowitz on Building Organizational Resilience & Navigating Macro Uncertainty
Ben Horowitz, co-founder of a16z and veteran tech entrepreneur, and David Solomon, Goldman Sachs CEO leading a tech-driven overhaul, discuss macro tailwinds, AI reshaping competitive moats, crypto and AI policy, and Goldman’s One GS 3.0 push to reimagine core banking processes with automation. They explore M&A and IPO prospects and whether AI agents can change investing.
277 snips
Jan 30, 2026 • 58min
“Anyone Can Code Now” - Netlify CEO Talks AI Agents
Matt Biilmann, Netlify CEO and Jamstack creator, describes a surge of nontechnical users building web apps via AI prompting. He explains agent-driven workflows, new debugging patterns with LLMs, shifting economics toward usage-based pricing, and how browsers and platforms must evolve to serve agents and humans differently.
990 snips
Jan 29, 2026 • 1h 41min
Marc Andreessen on Why This Is the Most Important Moment in Tech History
Marc Andreessen, venture capitalist and Netscape co-creator, reflects on why 2025 may be a turning point in technology. He discusses how AI is reshaping product, design, and engineering roles. He explores whether AI can democratize tutoring, how founders should think about AI-native companies, and which skills to teach kids for an AI-driven future.
225 snips
Jan 28, 2026 • 43min
Ben Horowitz and Balaji Srinivasan on Netscape and Network States
Ben Horowitz, a16z co-founder and veteran Silicon Valley exec who led Netscape and Opsware, joins a wide-ranging chat. They trace how tech primitives like crypto, digital identity, and wallets can assemble into new internet-native institutions. Conversations jump from Shenzhen-style experiments to pop-up startup societies, pro-tech jurisdictions, and where code can and cannot replace traditional legal and governance systems.
352 snips
Jan 27, 2026 • 1h 34min
Healthcare 2026: AI Doctors, GLP-1s, and Insurance Defection
Nikhil Krishnan, founder of Out-of-Pocket who helps people navigate U.S. healthcare, explores why insurance is fracturing and more consumers are paying cash. He digs into AI-driven screening and regulatory tensions, the boom in at-home diagnostics and wearables, and the rise of GLP-1s, peptides, and gray-market risks. Short, sharp takes on how care and choice are shifting.
606 snips
Jan 26, 2026 • 1h 4min
The Hidden Economics Powering AI
David George, a16z General Partner focused on growth-stage AI and enterprise software, outlines how AI reshapes private markets. He discusses why companies stay private longer. He covers massive AI infrastructure capex, falling model costs and rapid capability gains. He explores pricing and monetization experiments, durable use cases, and how portfolio construction adapts to this new AI landscape.
234 snips
Jan 23, 2026 • 45min
How Mintlify Is Rebuilding Documentation for Coding Agents
Hahnbee Lee, co-founder focused on product intuition and developer experience, and Han Wang, co-founder building docs-as-infrastructure, join to discuss how documentation is evolving. They talk about Mintlify’s many pivots, landing early customers with fast prototypes and white-glove onboarding, and why docs now power AI coding agents, internal knowledge flows, and self-updating doc systems.
