This Week in Virology

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Ted Diehl and Welkin Johnson Ted and Welkin inform the TWiV team how the evolution of ancient retroviruses can be inferred by studying their sequences in the genomes of modern mammals, and join in a discussion of virus dispersal during different methods for drying hands. Links for this episode More fun than a monkey full of viruses (TWiV 122) Tracking ancient retrovirus evolution in mammals (eLife) Virus dispersal during hand drying (J Appl Micro) More than you wanted to know about hand drying (one, two, three, four, five, six) This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016 Weekly Science Picks 1:30:20 Welkin - Lab Girl by Hope Jahren (essay)Ted - Accidental brilliance in scienceRich - Perpetual motion?Kathy - R0 graphic and explanationVincent - NWS ditches all caps forecasts Listener Picks Basel - Gimli Glider and Mars Climate OrbiterKen - Vaccination comic book Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello and Dickson Despommier Guest: Stuart Firestein Stuart joins Vincent and Dickson to talk about his sequel to Ignorance, a book called Failure, which seeks to make science more appealing by revealing its faults. Links for this episode Stuart Firestein's site Ignorance with Stuart Firestein (TWiV Special) The pursuit of ignorance (TED) Ignorance by Stuart Firestein Failure by Stuart Firestein This episode is sponsored by ASM Agar Art Contest and ASV 2016 Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Rich Condit Guests: Nischay Mishra and Ian Lipkin Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed, and new vaccines to prevent dengue virus infections, including a human challenge model. Links for this episode Novel orthomyxo-like virus in Tilapia die-offs (mBio) Fish flu (TWiV 41) Anti-vaccination lunacy won't stop (WSJ) Single-dose dengue vaccine effective (J Inf Dis) Dengue vaccine needs (J Inf Dis) Composition of TV003 (J Inf Dis) Dengue vaccine mutagenesis (Curr Top Micr Imm) Dengue human challenge model (Sci Transl Med) Yellow fever alarm (STAT) Experiment: Zika virus UC Berkeley Microbiology Student Symposium Image credit Letters read on TWiV 384 This episode is sponsored by ASM Agar Art Contest, ASM Grant Writing Course, and ASV 2016 Weekly Science Picks Rich - Dune by Frank HerbertAlan - Adult vaccination video contestDickson - Ski town greenhouseVincent - Preprint servers: Force awakens or revenge of undead? Listener Picks Ken - Golden Mole Awards for Accidental Brilliance (list, video)Jim - Linear algebra course Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler Guest: Esper Kallas Esper and the Merry TWiXters analyze the latest data on Zika virus and microcephaly in Brazil, and discuss publications on a mouse model for disease, infection of a fetus, mosquito vector competence, and the cryo-EM structure of the virus particle. Links for this episode Zika virus in the Americas (Science) Co-circulation of dengue, Zika, chik in Brazil (Medicine) Murine model for Zika virus infection (Am J Trop Med Hyg) Zika virus susceptibility of A. aegypti and A. albopictus (PLoS NTD) Infectious Zika virus from saliva (EuroSurveill) Zika virus spread through saliva? (Braz Oral Res) Five Zika virus reviews (one, two, three, four, five) Zika virus and microcephaly, Brazil (MMWR) Zika virus in urine (EuroSurveill) Zika virus infection of fetus (NEJM) Real-time sharing of Zika virus data (JAMA) Image credit: Richard Kuhn Letters read on TWiV 383 This episode is sponsored by ASM Agar Art Contest and ASV 2016 Weekly Science Picks Esper - The Chaos by Gérard Nolst Trenité and HIV pathogenesis courseAlan - Science KombatDickson - Four steps to wiping out a mosquitoVincent - Public lacks information on Zika virusKathy - Zika virus cryo-EM structure video Listener Picks Justin - Culture-independent discovery of Archaeal virusMelinda - Zika virus open research portal and Your body battles series Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Kathy Spindler Guests: Nels Elde and Edward Chuong Nels and Ed join the TWiV team to talk about their observation that regulation of the human interferon response depends on regulatory sequences that were co-opted millions of years ago from endogenous retroviruses. Links for this episode Endogenous retroviruses and regulation of innate immunity (Science) Placenta is viral (Nature) An ERV that maintains pluripotency of human embryonic stem cells (TWiV 279) Letters read on TWiV 382 This episode is sponsored by ASM Agar Art Contest and ASV 2016 Weekly Science Picks Nels - Don't Get Me Started - Matt GiorgianniAlan - Sun's magnetic field (paper)Dickson - Most realistic dinosaur terrifiesVincent - Top secret!Kathy - Zika virus risk for US 50 cities (paper)Ed - Watching comb jellies poop Listener Picks Asal - Lost paper of Gregor MendelDennis - PhysicsGirlJacob - Second (XKCD) and ACI blogger interview Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Carl Zimmer Carl Zimmer joins the TWiV team to talk about his career in science writing, the real meaning of copy-paste, science publishing, the value of Twitter, preprint servers, his thoughts on science outreach, and much more. Links for this episode Carlzimmer.com All Carl's articles at NYTimes Carl at Stat The Loom Staying afloat in the rising tide of science (Cell) Parasite Rex Planet of Viruses Handful of biologists went rogue (NYTimes) This episode is sponsored by ASV 2016 and ASM Agar Art Contest Weekly Science Picks Carl - Surprising benefit of viral DNAAlan - Global ship trafficDickson - Music with 2000 marblesVincent - The whiteboard revolutionKathy - How to interpret UK and American advisorsRich - Carina Storrs, science writer Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVeroos deliver the weekly Zika Report, then talk about a cryoEM structure of a plant virus that reveals how the RNA genome is packaged in the capsid, and MIMIVIRE, a CRISPR-like defense system in giant eukaryotic viruses. Links for this episode First worms, then viruses, now dormant cyber pathogens (Zdziarski blog) Guillain-Barré with Zika virus in urine (Eurosurveillance) Zika virus in urine, Brazil (J Clin Virol) Zika in pregnant women in Rio (NEJM) Issues with NEJM pregnant women study (Epi-Ramble) Zika virus and meningoencephalitis (NEJM) Zika virus and acute myelitis (Lancet) Person to person transmission of Zika virus (MMWR) Pyrethroids and mouse microcephaly (one, two) Zika virus illustrations (Visual Science) Cowpea mosaic virus at high resolution (Nat Comm) MIMIVIRE confers resistance to virophage (Nature) CRISPR in a phage (TWiM 56) National Academy of Sciences GoFoc meeting Image credit Letters read on TWiV 380 This episode is sponsored by ASM Agar Art Contest and Microbe Magazine Podcast Weekly Science Picks Alan - Progression of EvolutionDickson - Toddler dies of meningitisVincent - Gardasil ideology, not scienceKathy - The Noun ProjectRich - Physics Girl Listener Pick Mark - MyRadar app (iOS, Android) Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Scott Tibbetts Scott Tibbetts joins the TWiVists to describe his work on the role of a herpesviral nocoding RNA in establishment of peripheral latency, and then we visit two last minute additions to the Zika virus literature. Links for this episode Noncoding RNA required for establishment of latency (mSphere) 17:20 Lessons learned from in vivo studies of a viral noncoding RNA (mSphere) 1:05:05 Zika virus in pregnant women in Rio de Janeiro (NEJM) 1:06:10 Zika virus infects cortical neural progenitors (Cell Stem Cell) 1:12:00 Image credit Letters read on TWiV 379 1:15:10 This episode is sponsored by 32nd Clinical Virology Symposium and Microbe Magazine Podcast 4:15, 1:05:25 Weekly Science Picks 1:42:45 Alan - Okeanos ExplorerDickson - Rome RebornVincent - Twitter Missing ManualScott - Best Science Images of 2015Kathy - Space Travel PostersRich - GoISSWatch Listener Pick Peter - Antibiotics and the Problem of the Broken Market Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guests: Greg Smith and Mark Fuccio Greg Smith joins the TWiVirate to reveal how his lab discovered a switch that controls herpesvirus neuroinvasion, and then we visit the week's news about Zika virus. Links for this episode Dynamic ubiquitination drives herpesvirus neuroinvasion (PNAS) Releasing Zika virus data in real time (Nature) Zika virus infection and stillbirths (PLoS NTD) Zika virus infection, imported, Italy (Eurosurveillance) Letters read on TWiV 378 This episode is sponsored by 32nd Clinical Virology Symposium and Microbe Magazine Podcast Weekly Science Picks Alan - Science byline counting projectDickson - Bill Nye on climate changeVincent - Zdziarski's blog of things (Apple's motion to vacate)Greg - Atlas, the next generationKathy - Sources of Chaco woodMark - How Dogs Love Us by Gregory Berns Listener Pick Bohdan - The real reason for brains Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVniks review the past week's findings on Zika virus and microcephaly, and reveal a chicken protein that provides insight on the restriction of transmission of avian influenza viruses to humans. Links for this episode Larvicide not involved in microcephaly (CBS News) Obama seeks $1.8b for Zika virus (Guardian) Zika virus in Puerto Rico (MMWR) Zika virus in semen (EID) Zika virus in Indonesia (EID) Phylogeny of Zika virus (EID) Zika virus may cause mental disease (NYTimes) Zika virus from amniotic fluid (Lancet) Host protein underlies avian influenza host restriction (Nature) Wendy Barclay on TWiV 177 Home to roost (Cell) Image credit Letters read on TWiV 377 This episode is sponsored by 32nd Clinical Virology Symposium and Microbe Magazine Podcast Weekly Science Picks Alan - CDC vaccine quizDickson - A telescope so powerfulVincent - Virology Lectures 2016 (virology blog, iTunes U)Rich - Ion propulsion (Wiki)Kathy - Spurious Correlations Listener Pick Johnye - Magellan telescope and van Egmond photograpy at Kids Should See This Send your virology questions and comments to twiv@microbe.tv