This Week in Virology

Host: Vincent Racaniello Guest: Peter Palese Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines. Become a patron of TWiV! Links for this episode Palese Laboratory Pig kidney neuraminidase (Hoppe Seylers Z Physiol Chem) DNAse in cytoplasmic DNA virus (Virology) Inhibitor of influenza virus neuraminidase (Virology) Influenza neuraminidase defective mutants (Virology) Swine influenza virus of 1976 RNA pattern (Nature) 1977 influenza H1N1 similar to 1950s strains (Nature) H5N1 influenza: Facts, not fear (PNAS) Influenza HA stalk immunity in ferrets (J Virol) This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guest: Stephen J. Russell From ASV 2016 at Virginia Tech, Vincent, Rich and Kathy speak with Stephen Russell about his career and his work on oncolytic virotherapy - using viruses to treat cancers. Become a patron of TWiV! Links for this episode Hokies go viral (TWiV 285) MV NIS de Myelo (TWiV 298) Remission of disseminated myeloma after MV treatment (Mayo Clin Proc) miRNA detargeting (J Virol) Video of this episode at YouTube This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Weekly Science Picks Kathy - Can you explain your science in 30 seconds? and How Far Can We Go?Rich - Small asteroid Earth's companionVincent - The Gene by Siddhartha Mukherjee Listener Picks Dylan - Microsculpture by Levon Biss (website) Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello and Alan Dove Guest: Erica Ollmann Saphire Vincent and Alan speak with Erica about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA. Become a patron of TWiV! Links for this episode Structure of antibodies bound to Ebola virus glycoprotein (PNAS) Structure of cross-reactive filovirus antibody (Cell) Multiple functions of Ebola virus VP40 protein (Cell) View video of this episode on YouTube Letters read on TWiV 394 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Weekly Science Picks Alan - Slime LapseVincent - Virus Watch Listener Picks Patricia - NECSS, People Behind the Science, The Life Scientific Peter - Iron Lung on eBay Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiVerati revisit possible sexual transmission of Zika virus, and reveal how a cell protein that allows hepatitis C virus replication in cell culture enhances vitamin E mediated protection against lipid peroxidation. Become a patron of TWiV! Links for this episode Late sexual transmission of Zika virus (Lancet) Zika virus disease in US (CDC) Zika virus lab accident (ABC News) Mosquito eradication (virology blog) Florida mosquito control (TWiV 111) How tequila mosquito (TWiV 178) SEC14L2 allows HCV replication in cell culture (Nature) Lipid peroxidation (Wikipedia) HCV replicase regulated by lipid peroxidation (Nat Med) Letters read on TWiV 393 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Alan - All About That SpaceRich - The Expanse by James S.A. Corey (SyFy) Kathy - Five Pivotal Paragraphs in a PaperVincent - Agar Art Contest Winners Listener Picks Ted - Marshall Niremberg charts Send your virology questions and comments to twiv@microbe.tv

Host: Vincent Racaniello Guests: Michael Diamond, Michaela Gack, Laura Kramer, and Charles Rice Four virologists discuss our current understanding of Zika virus biology, pathogenesis, transmission, and prevention, in this special live episode recorded at the American Society for Microbiology in Washington, DC. [powerpress url="http://traffic.libsyn.com/twiv/TWiV392.mp3"] Click arrow to play Download TWiV 392 (62 MB .mp3, 85 min) Subscribe (free): iTunes, RSS, email, Google Play Music Video of this episode at YouTube This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Guests: David Pride and Forest Rohwer If you have always wanted to know what coral reefs and the human oral cavity have in common, listen as guests David Pride and Forest Rohwer talk about their work on the microbiomes and viromes of these two environments, and you'll also understand why mucus is cool. Links for this episode Lytic to temperate switching of viral communities (Nature) Viromes in ancestral holobiont Hydra (PLoS One) Phage in human oral cavity (J Oral Micro) Human oral viruses are personal, consistent, gender specific (ISME) Video of this episode at YouTube This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Weekly Science Picks Alan - Vax Pack HeroRich - Helicopter autorotation Vincent - Live in Our Phage World by Forest Rohwer, Merry Youle, Heather Maughan, Nao Hisakawa Listener Picks Matt - Experiment.com Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guests: Ethan Jackson and Jonathan Carlson Project Premonition, a Microsoft Research project that uses drones to capture mosquitoes and analyze them for pathogens, preprint servers, and three mouse models for Zika virus induced birth defects are the topics of this episode hosted by the TWiumvirate and theirs guests Ethan and Jonathan. Links for this episode Project Premonition Premonition feasibility study in Grenada Zika virus causes microcephaly in mice (Cell Stem Cell) Brazilian Zika virus causes defects in experimental models (Nature) Zika virus causes placental damage and fetal demise in mice (Cell) Letters read on TWiV 390 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Dickson - Germany nearly reached 100% renewable power Alan - Vertical City documentary and Lumino City gameRich - Errol Morris: 'Demon in the Freezer' Kathy - Entropic Time YouTube by A Capella Science (watch "the making of")Vincent - Agar Art contest finalists Listener Picks Jennie - SciFi reading (scroll down) Send your virology questions and comments to twiv@microbe.tv

Host: Vincent Racaniello Guest: Stan Lemon Vincent speaks with Stan Lemon about his career in virology, from early work on Epstein Barr virus, through making essential discoveries about hepatitis A virus, hepatitis C virus, and rhinoviruses. Links for this episode Live in Edmonton, Eh? (TWiV 235) Replication of EBV in epithelial cells (Nature) Returning to Carolina after 14 years Evolutionary origins of hepatitis A virus (TWiV 265) cre in rhinovirus genome (RNA) Naked viruses that aren't always naked (Ann Rev Virol) miR-122 and hepatitis C virus RNA (Cell Host Micr) This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Preprint servers, the structure of an antibody bound to Zika virus, blocking Zika virus replication in mosquitoes with Wolbachia, and killing carp in Australia with a herpesvirus are topics of this episode hosted by Vincent, Dickson, Alan, and Kathy. Links for this episode biorXiv preprint server Please review Vaccines and Your Child Structure of antibody bound to Zika virus E protein (Cell Host Microbe) Wolbachia blocks Zika virus in mosquitoes (Cell Host Microbe) Zimmer on Wolbachia and Zika virus (NY Times) Fauci on Zika virus vaccine (Science) Carpageddon (The Conversation) Letters read on TWiV 388 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Dickson - EarthEnv Alan - Research funding by lottery Kathy - Eugenia Cheng Math and BakingVincent - Zika Diaries Listener Picks Stephen - Virus trading cards William - Virus trading cards Norma+Maurice - Virus trading cards Tom - Virus trading cards Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Nina Martin Nina Martin joins the TWiV team to talk about the movie Vaxxed, her bout with dengue fever, and the latest research on Zika virus. Links for this episode Public Health United Fifty Shades of Science (TEDx) Parents convicted in death of toddler (Science Based Medicine) CDC: Zika virus causes microcephaly (NEJM) Dengue virus antibodies enhance Zika virus infection (biorXiv) Zika virus in Brazilian nonhuman primates (biorXiv) Zika virus IgM in CSF of microcephalic babies (Lancet) Brain organoids for modeling Zika virus infection (Cell) Letters read on TWiV 387 This episode is sponsored by CuriosityStream. Get two months free when you sign up at curiositystream.com/microbe and use the promo code MICROBE. Also brought to you by ASV 2016 Weekly Science Picks Nina - Vaccines and Your Child by Paul Offit and Charlotte MoserDickson - The animals of Chernobyl Alan - Five rules of lab safety Kathy - 20 best science images of the year?Vincent - Massive undersea crab swarm Listener Picks JP - Global map of wind Todd - Doc Martin Send your virology questions and comments to twiv@microbe.tv