This Week in Virology

The TWiV team discuss the biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding proteins are at the sides. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker Become a patron of TWiV! Links for this episode Support Viruses & Cells Gordon Conference Outbreak at the Smithsonian Outbreak (TWiV 501) Latest Ebola virus outbreak, DRC (WHO) Summary of Ebola virus outbreaks (CDC) Ebola virus nomenclature (ICTV) Ebola virus distribution map (CDC) Polarization of vaccinia virus membrane proteins (bioRxiv) Image credit Letters read on TWiV 507 Weekly Science Picks Alan - Puzzled Escape Games Rich - An Extremely Detailed Map of the 2016 Election Dickson - Parker Solar ProbeKathy - Ancient earth globe and connected Dinosaur database Brianne - STEMM education should get HACD Vincent - Free tuition for all NYU medical students Listener Pick Heather- GoFarm blog Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

David Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS. Host: Vincent Racaniello Guest: David Tuller Become a patron of TWiV! Links for this episode Articleby Lubet and Tuller (STAT) David's Australian trip (virology blog) Sir Simon scores own goal (virology blog) Lightning process (virology blog) Letter to Parliament (virology blog) Crowdfunding is not conflict of interest (virology blog) Open letter to Lancet 3.0 (virology blog) Mayo still champions GET (virology blog) Image Credit Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker Become a patron of TWiV! Links for this episode Support Viruses & Cells Gordon Conference New DRC Ebola strains distinct (Outbreak News) Immunizations for new DRC Ebola outbreak (The Scientist) Structure of Cafeteria roenbergensis virus (Sci Rep) Chuan (River) Xiao laboratory CroV movies Scaled deployment of Wolbachia(Gates Open Res) In the wake of Wakefield (BBC) Letters read on TWiV 506 Weekly Science Picks Alan - Ebola research begins at the NEIDL Dickson - Science Photo Library Brianne - First liquid water (underground lake) found on Mars Vincent - Thirty years ago, we could have saved the planet Listener Pick Edmund- STEM talk Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer's disease. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler and Brianne Barker Become a patron of TWiV! Links for this episode Support Viruses & Cells Gordon Conference Trump picks science advisor (Scientist) Hendra vaccine: no effect on horses racing (Aust Vet J) Persistence of Ebola virus (Lancet Inf Dis) New Ebolavirus outbreak (Telegraph) Alzheimer's disease and herpesviruses (Neuron) Herpesviruses, beta-amyloid and Alzheimer's disease (Neuron) Letters read on TWiV 505 Weekly Science Picks Alan - Impossible Burger Rich - SpaceX Just Sent Algae to the ISS, Here's How It'll Power Deep Space Missions Dickson - Art and Science Intersection (Art Science Museum) Brianne - Why it is not a 'failure' to leave academia Kathy- 2003 video history of nuclear explosions 1945 - 1998 Vincent - Revisionist History Episode 8 and Episode 9 Listener Pick Mark- TWIV bingo (png) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Brianne Barker Become a patron of TWiV! Links for this episode Support Viruses & Cells Gordon Conference TWiV 501: Outbreak Nipah virus infection (JCM) Anatomy of an outbreak (The Hindu) Do we need to worry about Nipah virus? (Tufts Now) Nipah virus infection of bats (EID) Papua New Guinea no longer polio-free (virology blog) WHO polio endgame (polioeradication) Letters read on TWiV 504 Weekly Science Picks Alan - Glaciers of the Rockies aerial photos Rich - SpaceX CRS-15 mission to the space station(wiki) Dickson - Test of Einstein's theory of relativity Brianne - biorender Vincent - True or False? with Michael Schmidt Listener Pick Jolene- Dogs cannot get autism Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Vincent, Rich and Kathy travel to ASV 2018 at the University of Maryland to speak with Svetlana Folimonova and Anne Simon about their work on viruses that infect plants. Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Svetlana Folimonova and Anne Simon Become a patron of TWiV! Links for this episode Simon laboratory Folimonova laboratory CTV superinfection exclusion (Virol) 3'-CITEs in viral genome (J Virol) Video of this episode (YouTube) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiV team travels to Texas A&M University, home of the Center for Phage Technology, where they speak with Ry Young and Jason Gill about their work on viruses that infect bacteria. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guests: Jason Gill and Ry Young Become a patron of TWiV! Links for this episode Center for Phage Technology at TAMU Personalized phage therapy (PNAS) Phage for biolipid extraction (Sci Rep) Viral protein antibiotic (Nat Micro) Acinetobacter phage depolymerase (J Virol) Structure of phage Qβ (PNAS) Video of this episode (YouTube) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Vincent visits the Smithsonian Institution and speaks with Sabrina Sholts, Jon Epstein, and Ed Niles about the exhibit Outbreak: Epidemics in a Connected World. Host: Vincent Racaniello Guests: Sabrina Sholts, Jon Epstein, and Ed Niles Become a patron of TWiV! Links for this episode Sabrina Sholts Jonathan Epstein EcoHealth Alliance Outbreak at the Smithsonian ASM partners with Smithsonian (bLog Phase) Vincent as museum object (AMNH) Video of this episode (YouTube) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The entire TWiV team visits The University of Texas in Austin to record episode #500 with guests Jinny Suh, Jason McClellan, and Jon Huibregtse. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guests: Jinny Suh, Jason McClellan, and Jon Huibregtse Become a patron of TWiV! Links for this episode A big list of science podcasts Immunize Texas McClellan Lab Huibregtse Lab John Ring LaMontagne Center for Infectious Disease Video of this episode (YouTube) Weekly Science Picks Alan - The Airplane Cabin Microbiome Rich - Coalition for Epidemic Preparedness Innovations (CEPI)(wiki) Dickson - The Big Five Mass Extinctions Kathy - Virus scarves at Red Bubble phage-specific variety Vincent - Science podcasts Listener Pick Maureen- 12 year old takes on Flint's Water Crisis Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Vincent and Alan travel to the Canadian Society for Virology meeting in Halifax, Nova Scotia to speak with Nathalie and Craig about their vision for the society, and with Kate and Ryan about their careers and their research. Hosts: Vincent Racanielloand Alan Dove Guests: Nathalie Grandvaux, Craig McCormick, Kate O'Brien, and Ryan Noyce Become a patron of TWiV! Links for this episode TWiV 2018 World Tour CSV 2018 To wheeze or not to wheeze (Lancet Respir Med) Synthetic infectious horsepox (PLoS One) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv