

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

53 snips
Dec 10, 2024 • 1h 7min
How Google X’s Mo Gawdat Made 1 Billion People Happier - Including YOU (Part 1) : 1230
Mo Gawdat, bestselling author of "Unstressable" and former Chief Business Officer of Google X, reveals his groundbreaking approach to happiness. He explains how happiness can be engineered through a unique algorithm that you can apply to your life. Mo discusses the dark side of dopamine and how to reclaim joy, while breaking down the four types of stress and effective biohacks like cold plunges and gratitude practices. His personal journey from tragedy to purpose offers profound insights on resilience and the true source of fulfillment.

148 snips
Dec 5, 2024 • 1h 43min
Is Red Meat the Fountain of Youth? Paul Saladino : 1229
Paul Saladino, a leading physician and author of 'The Carnivore Code,' shares his insights on nutrition and the evolution of diets. He emphasizes the importance of metabolic flexibility over strict rules, challenging common beliefs about ketosis and caloric restriction. Saladino critiques so-called health foods like quinoa, advocates for nutrient-dense animal products, and highlights the health implications of seed oils. Their discussion also covers balancing omega fatty acids, the significance of organ meats, and the role of mTOR in achieving longevity.

102 snips
Dec 3, 2024 • 1h 11min
Why is your Oral Health KILLING you, and what can you do about it?! Naveen Jain : 1228
Naveen Jain, founder and CEO of Viome Life Sciences, discusses the critical link between oral health and overall well-being. He reveals how imbalances in oral bacteria may lead to chronic diseases and explains why traditional mouthwashes can be detrimental. Jain offers innovative solutions to optimize your oral microbiome for longevity, including personalized lozenges and dietary advice. Listeners will learn actionable tips for enhancing their oral health and how to make lifestyle choices that significantly influence health outcomes.

35 snips
Nov 28, 2024 • 1h 12min
What You DON'T Know About Women’s Health! From Microbiome to Major Impact with Priyanka Jain : 1227
Priyanka Jain, Co-founder and CEO of Evvy, explores the transformative power of the vaginal microbiome for women's health. She discusses how it affects everything from fertility to hormonal balance and common issues like bacterial vaginosis and UTIs. Jain emphasizes the need for personalized health approaches and innovative solutions, including the use of AI and genomic research. The conversation also highlights the significant impact of lifestyle and hormonal changes on microbiome health, paving the way for better reproductive health outcomes.

71 snips
Nov 26, 2024 • 1h 7min
The World’s BEST Alcohol Alternative. Pleasure, Relaxation, and Clarity with TRU KAVA : 1226
Cameron George, founder of TRU KAVA, discusses the rise of kava as a healthier alternative to alcohol. He explains how kava promotes relaxation and mental clarity while enhancing social connections. The conversation dives into kava's impact on neurotransmitters like GABA and dopamine, its role in reducing anxiety, and its therapeutic benefits for creativity and stress relief. Cameron also shares insights on kava's cultural significance and its potential in the sober-curious movement, making it a compelling option for those seeking a more connected lifestyle.

38 snips
Nov 22, 2024 • 59min
Urolithin A’s Secret to YOUTHFUL ENERGY and the Fight Against Inflammaging : 1225
Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition, unpacks the revolutionary postbiotic Urolithin A, crucial for mitochondrial health and energy. He discusses how it helps reverse 'inflammaging' and boosts immunity through dietary strategies and fasting. Dr. Singh highlights Urolithin A's role in enhancing athletic recovery and skin health, showing its potential to rejuvenate both cellular energy and appearance. Practical tips for leveraging nutrition to improve resilience against aging are also shared, making it a vital listen for anyone interested in longevity.

75 snips
Nov 21, 2024 • 1h 11min
Exosomes vs Stem Cells and LIFE-CHANGING Advice with Harvard Physician Dr. Edward Park : 1224
Dr. Edward Park, a Harvard-trained physician and regenerative medicine pioneer, dives into the fascinating world of exosomes. He reveals how these tiny messengers are transforming healing and longevity, offering a potent alternative to traditional stem cell therapies. Beyond science, Dr. Park shares profound wisdom on emotional resilience and the importance of forgiveness. He emphasizes the role of gratitude and breaking limiting beliefs as keys to a fulfilling life. This insightful conversation bridges the gap between groundbreaking medicine and personal empowerment.

116 snips
Nov 19, 2024 • 50min
Is Infrared Light the KEY to Longevity? Detox, Recovery, and Increased Energy with Sunlighten Saunas : 1223
Connie Zak, founder of Sunlighten and an expert in infrared sauna technology, joins the conversation to delve into the health benefits of infrared light therapy. They explore how infrared saunas can detox heavy metals, mimic exercise for cardiovascular health, and boost cellular energy for longevity. The discussion highlights innovative advancements in sauna technology and practical tips for maximizing sauna sessions. Connie shares insights on gut health improvement, inflammation reduction, and the power of targeted light for overall well-being.

42 snips
Nov 14, 2024 • 1h 46min
How to Discover What You TRULY Want—and Ask for It! Featuring the Author of Dave’s Top Book for Women : 1222
Kasia Urbaniak, founder and CEO of The Academy and author of "Unbound: A Woman's Guide to Power," is an expert in influence and authority. She discusses how to set unbreakable boundaries and wield influence with integrity. Kasia shares techniques for reclaiming inner authority and navigating complex power dynamics in various relationships. With insights from her unique background in Taoist alchemy and professional dominance, she empowers women to transform their self-perceptions and command any room with confidence.

123 snips
Nov 12, 2024 • 1h 24min
How to Optimize Your Brain for WORK: Achieving Hyper-Efficiency with Dr. Mithu Storoni : 1221
Dr. Mithu Storoni, a neuroscientist and author of "Hyper Efficient," delves into how to unlock your brain's potential for peak work performance. She discusses the critical roles of astrocytes and the locus coeruleus in enhancing focus and mental clarity. Discover effective ways to harness neuroplasticity and optimize breathing rhythms to improve productivity despite distractions. Stoics principles like managing arousal states and synchronizing with ultradian rhythms reveal how to boost your cognitive efficiency and resilience in high-pressure environments.


