Modern Healthspan

In this video Professor Sebastiano discusses how the timing of the therapy might work, concerns of whether the "point of no return" might be crossed and what aspects of aging are not covered by partial cellular reprogramming. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERNnew5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Professor Sebastiano discusses the three most advanced interventions that Turn Bio is working on, for skin, immunology and muscles and when they will be available for human trial. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERNnew5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERNnew5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Professor Sebastiano discusses the results that he and his team have had in rejuvenating human cells and how the process could be applied as well as their experience rejuvenating a muscle in an old mouse. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this video Professor Sebastiano discusses how the mRNA is delivered to the specific cells and how the recent explosion of mRNA interest has changed the development landscape. Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Professor Sebastiano introduces ERA, Epigenetic Reprogramming of Age technology and talks about his thoughts on some of the causes of aging Professor Vittorio Sebastiano manages a lab in Stanford University which developed and patented technology for partial cellular reprogramming. He co-founded Turn Bio, where he is now Head of research, to translate this technology into clinical applications. And with that, let me start the interview. Turn Bio website https://www.turn.bio/ Professor Sebastiano's lab at Stanford https://med.stanford.edu/stemcell/institutefaculty/sebastiano.html Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells https://pubmed.ncbi.nlm.nih.gov/32210226/ NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ 15% Discount on Renue By Science with Code MHS15 until May 01 2023 ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Dr Newman talks about ketones as a fuel for the brain and how this becomes more important as we age and the brain can become less able to use glucose. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that control aging, with a focus on ketone bodies. Dr Newman's lab at the Buck Institute https://www.buckinstitute.org/lab/newman-lab/ And at University of California, San Francisco. https://medicine.ucsf.edu/people/john-newman NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Dr Newman talks the ITP lifespan trials that used butanediol but did not see a significant result. He covers what might have caused this and some of the chemistry behind butanediol and butyrate. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that control aging, with a focus on ketone bodies.   Dr Newman's lab at the Buck Institute https://www.buckinstitute.org/lab/newman-lab/ And at University of California, San Francisco. https://medicine.ucsf.edu/people/john-newman   NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Dr Newman talks ways of boosting ketones through ketone supplements, what the different types are and what has been seen with them in human trials. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that control aging, with a focus on ketone bodies. Dr Newman's lab at the Buck Institute https://www.buckinstitute.org/lab/newman-lab/ And at University of California, San Francisco. https://medicine.ucsf.edu/people/john-newman NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ ProHealth 10% of all products Code MODERN : https://www.prohealth.com/

In this episode Dr Newman talks about experiments that he and other teams have run on mice lifespan and healthspan while they were on ketogenic diets. Dr John Newman is a professor at the Buck Institute and at University of California, San Francisco. He hopes to translate what we are learning of the pathways that control aging into therapies to improve the health and independence of older adults. His research at the Buck studies the molecular details of how diet regulate the pathways that control aging, with a focus on ketone bodies. Dr Newman's lab at the Buck Institute https://www.buckinstitute.org/lab/newman-lab/ And at University of California, San Francisco. https://medicine.ucsf.edu/people/john-newman   NOVOS Core & NOVOS Boost https://novoslabs.com/?ref=3957 $5 off any purchase if users use code MODERN5 10% off DoNotAge all products with discount code MODERNHEALTHSPAN https://donotage.org/products/ 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ ProHealth 10% of all products Code MODERN : https://www.prohealth.com/