Modern Healthspan

Here Dr Maroon, discusses his path to becoming a triathlete, his exercise protocol and his experience with hyperbaric oxygen therapy. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the University of Pittsburgh Medical Center and has been the team neuroscientist for the Pittsburg Stealers since 1980. After starting to compete in triathlons in his 40’s he has completed more than 70 Olympic distance events including 8 international ironman’s. His most recent was in August 2022 at the age of 82 where he finished first in his age group.. 🌐Links in this episode Dr Maroon's website https://www.josephmaroon.com/ The effect of hyperbaric oxygen therapy on cognition, performance, proteomics, and telomere length—The difference between zero and one: A case report https://www.frontiersin.org/articles/10.3389/fneur.2022.949536/full Dr Maroon's books on Amazon Square One: A Simple Guide To A Balanced Life-2nd Edition https://amzn.to/3GzICNg Omega-3 for Optimal Life: Why You Need Fish Oil https://amzn.to/3Rz68QU The Longevity Factor: How Resveratrol and Red Wine Activate Genes for a Longer and Healthier Life https://amzn.to/48a9m2D products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Dr Elena Seranova, serial entrepreneur with an MSc in Translational Neuroscience and a PhD in Stem Cell Biology and Autophagy, talks about the supplements she takes and a hack for getting better deep sleep. The episode also mentions a new brain supplement now available and discusses the benefits of supplementing with melatonin for aging individuals. Additionally, Calcium Alpha-Ketoglutarate is explored as a popular longevity supplement.

Dr Elena Seranova, serial entrepreneur with an MSc in Translational Neuroscience and a PhD in Stem Cell Biology and Autophagy, discusses her diet and exercise choices. Topics include the impact of diet on hormone levels, challenges of obtaining protein in a vegan diet, the importance of logic in assessing nutrition, and exercise routines for longevity and optimal health.

Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK. 🌐Links in this episode NMN Bio website: https://nmnbio.co.uk/ NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency https://www.sciencedirect.com/science/article/pii/S2211124723003832 Autophagy promotes cell survival by maintaining NAD levels https://pubmed.ncbi.nlm.nih.gov/36413951/ Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota https://sciencedirect.com/science/article/abs/pii/S0006291X23006538 Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease https://pubmed.ncbi.nlm.nih.gov/28330719/ 40 Hz frequency studies: Human study from MIT: https://picower.mit.edu/news/small-studies-40hz-sensory-stimulation-confirm-safety-suggest-alzheimers-benefits Parkinson's disease study: https://www.mdpi.com/2227-9032/8/2/113 Mouse study: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1129510/full10% NMN Bio 10% off all products https://tinyurl.com/2af2v2fw Code ModernHealthSpan10 in link Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Seranova answers some questions on the paper from the first interview (https://youtu.be/fsuhtgKUZRg). Particular topics we discuss, mitochondria fragmentation, de novo pathway in neurons, difference between NR & NMN. Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK. 🌐Links in this episode NMN Bio website: https://nmnbio.co.uk/ NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency https://www.sciencedirect.com/science/article/pii/S2211124723003832 Autophagy promotes cell survival by maintaining NAD levels https://pubmed.ncbi.nlm.nih.gov/36413951/ Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota https://sciencedirect.com/science/article/abs/pii/S0006291X23006538 Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease https://pubmed.ncbi.nlm.nih.gov/28330719/ 40 Hz frequency studies: Human study from MIT: https://picower.mit.edu/news/small-studies-40hz-sensory-stimulation-confirm-safety-suggest-alzheimers-benefits Parkinson's disease study: https://www.mdpi.com/2227-9032/8/2/113 Mouse study: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1129510/full10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Seranova talks through her latest paper on the impact of NAD precursors (NR & NMN) on autophagy in human neuron Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK. 🌐Links in this episode NMN Bio website: https://nmnbio.co.uk/ NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency https://www.sciencedirect.com/science/article/pii/S2211124723003832 Autophagy promotes cell survival by maintaining NAD levels https://pubmed.ncbi.nlm.nih.gov/36413951/ Nicotinamide mononucleotide improves the Alzheimer's disease by regulating intestinal microbiota https://sciencedirect.com/science/article/abs/pii/S0006291X23006538 Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease https://pubmed.ncbi.nlm.nih.gov/28330719/ 40 Hz frequency studies: Human study from MIT: https://picower.mit.edu/news/small-studies-40hz-sensory-stimulation-confirm-safety-suggest-alzheimers-benefits Parkinson's disease study: https://www.mdpi.com/2227-9032/8/2/113 Mouse study: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1129510/full10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala talks how to think about exercise routines and nutrition as well as sharing his own protocol and the current work of his lab Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter 🌐Links in this episode World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org Dr Gibala's web site https://martingibala.com/ His page at McMaster University https://experts.mcmaster.ca/display/gibalam Dr Gibala's Book on Amazon The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter https://amzn.to/45VCDNd 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala talks about what is VO2max, why it is important, how to measure and improve it. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter 🌐Links in this episode World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org Dr Gibala's web site https://martingibala.com/ His page at McMaster University https://experts.mcmaster.ca/display/gibalam Dr Gibala's Book on Amazon The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter https://amzn.to/45VCDNd 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Gibala introduces interval training and discusses the various styles, and the benefits. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the regulation of skeletal muscle energy metabolism, his laboratory conducts applied research that examines the impact of physical training and nutrition on human health and performance. He coauthored a book for the general public on the science of time-efficient exercise, The One-Minute Workout: Science Shows a Way to Get Fit That’s Smarter, Faster, Shorter 🌐Links in this episode World Fitness Level (online VO2max calculator) https://www.worldfitnesslevel.org Dr Gibala's web site https://martingibala.com/ His page at McMaster University https://experts.mcmaster.ca/display/gibalam Dr Gibala's Book on Amazon The One-Minute Workout: Science Shows a Way to Get Fit That's Smarter, Faster, Shorter https://amzn.to/45VCDNd 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/

Here Dr Patel talks about his topical glutathione treatment Glutaryl and the recent trial that was conducted at McGill University. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, consultant, and lecturer on the Master Antioxidant Glutathione. Dr. Patel founded Auro Wellness in 2011 to create products to help the body function at an optimal level and reduce the long-term impact of stress on the body. Through his research, Dr. Patel stabilized Glutathione, improved absorption, and increased its effectiveness with the Auro GSH™ Antioxidant Delivery System. He is the author of The Glutathione Revolution: Fight Disease, Slow Aging & Increase Energy, which addresses how powerful and essential Glutathione is to the body’s detoxification system and how to increase the body’s levels naturally. 🌐Links in this episode Auro Wellness https://aurowellness.com/ Paper using Auro Wellness Glutaryl Topical Absorption of Glutathione–Cyclodextrin Nanoparticle Complex in Healthy Human Subjects Improves Immune Response against Mycobacterium avium Infection https://www.mdpi.com/2076-3921/12/7/1375 Catch us on YouTube: https://www.youtube.com/c/modernhealthspan 10% Discount on Renue By Science products with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all products with discount code MHS https://donotage.org/products/ ProHealth 15% of all products Code MODERN: https://www.prohealth.com/