This Week in Evolution TWiEVO 84: Decoding our defenses to the Black Death
Nov 8, 2022
Exploring genetic changes during the Black Death, immune gene evolution, and smallpox eradication. Delving into ancient DNA and its impact on human evolution. Discussing genetic variations, immune defense mechanisms, and the influence of genetics on disease. Sharing anecdotes from Seattle visits and listener's inspiring journey to science. Wrapping up with gratitude and show notes information.
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Infectious Diseases and Evolution
- Infectious diseases are strong selective pressures in human evolution.
- This paper links specific genetic changes to the Black Death's impact.
Ancient DNA Analysis
- Researchers analyzed ancient DNA samples from London and Denmark, from before, during, and after the Black Death.
- This allowed them to study genetic changes related to the plague's impact.
ERAP2 and Plague Survival
- The study focused on ERAP2, a gene linked to immune response to the plague.
- Changes in ERAP2 are associated with increased survival rates.