Extend Podcast with Darshan Shah, MD 101. Dr. Mariza Snyder: Why 80% of Perimenopause Symptoms Are Brain Related and Doctors Keep Missing It
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Oct 7, 2025 
Dr. Mariza Snyder, a hormone and metabolic health expert, dives into the often-misunderstood realm of perimenopause. She reveals that 80% of perimenopause symptoms stem from brain issues, leading to significant misdiagnosis. Dr. Mariza discusses the importance of preventative hormone replacement therapy and tracking biomarkers from age 35. She shares practical steps for managing symptoms and emphasizes women's empowerment in advocating for their health, all while making the case for why this critical transition shouldn’t be suffered through.
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Physician Patient Dismissed Despite Severe Symptoms
- Dr. Snyder shared a story of a 30-year physician who struggled with disabling brain symptoms in late perimenopause and faced dismissal.
- The doctor had to advocate strongly to find a practitioner willing to prescribe hormones.
Watch For Subtle Early Signs In Your 40s
- Expect perimenopause symptoms to appear subtly in early 40s as reduced bandwidth and longer PMS phases.
- Track cyclical symptom timing to spot anovulatory cycles and progesterone loss.
Bring Lab Lists And A Support Person
- Know which labs you want and bring the reference list to your clinician; insist on functional ranges.
- Bring a support person to visits if needed to ensure your concerns get addressed.
