

Extend Podcast with Darshan Shah, MD
Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Episodes
Mentioned books

May 12, 2026 • 1h
163. Steve Chua: How Your Identity Is Either Healing Or Destroying Your Health
Steve Chua, executive life and leadership coach who helps leaders align identity and purpose. He tells his story of crisis and explains living for value versus from value. Short routines like phone-free mornings, solitude, and identity work reshape decisions and stress. Conversations cover false family narratives, letting go of fear, delegation struggles, and shifting from proving to being.

May 7, 2026 • 1h 15min
162. Dr. Meredith Broderick: What An Undiagnosed Sleep Disorder Is Quietly Doing To Your Brain And Body
Dr. Meredith Broderick, a triple board-certified sleep neurologist and founder of Sound Sleep Guru, blends medical, behavioral, and multidisciplinary approaches. She explores how undiagnosed sleep disorders mimic ADHD in kids, the hidden cardiovascular and cognitive toll of sleep apnea, connections between mouth breathing and airway issues, and practical fixes from CBT-I to structural and metabolic treatments.

May 5, 2026 • 47min
161. McCall McPherson: Why Your Thyroid Is Being Undertested And Undertreated
McCall McPherson, a licensed physician assistant and founder of Modern Thyroid Clinic who turned her own thyroid struggle into a nation‑wide telemedicine practice. She discusses why common thyroid tests miss the problem, the crucial role of free T3, life stages that spike thyroid risk, and why many patients remain undertreated despite feeling unwell.

6 snips
Apr 30, 2026 • 47min
160. Dr. Kara Fitzgerald on Biological Age, Epigenetic Clocks, and the Future of Aging Reversal
Dr. Kara Fitzgerald, a functional medicine physician and epigenetics researcher who studies how diet and lifestyle can reverse biological age. She discusses measuring biological vs chronological age, organ-specific epigenetic clocks, the role of polyphenols and postbiotics for mitochondria, exposomic drivers of aging, and emerging approaches like Yamanaka mimetics for controlled cellular reprogramming.

Apr 28, 2026 • 59min
159: Dr. Anurag Singh: Urolithin A, Mitophagy, and Mitochondrial Health
Dr. Anurag Singh, physician-scientist and Chief Medical Officer at Timeline, discusses urolithin A and mitochondrial health. He explains how the gut microbiome makes urolithin A, why many people do not produce it, and practical dosing choices. They cover mitophagy, drivers of mitochondrial damage, muscle and athletic recovery data, emerging brain and immune research, and when to consider supplementation.

Apr 23, 2026 • 1h 2min
158. Dr. Kavin Mistry: Primal Health Design, Biological Aging, and Reconnecting with Human Biology
Dr. Kavin Mistry, a neuroradiologist and author of Primal Health Design who studies how modern life reshapes brain and spine aging. He discusses tech neck and posture, primal movement and strength habits, morning sunlight and circadian reset, grounding and microbiome-supporting foods, and how connection, purpose, and routines restore resilience and longevity.

Apr 21, 2026 • 1h 4min
157. Dr. Tania Elliott: Allergies, Immune Health, and Hidden Toxins in Your Home
Dr. Tania Elliott, double board-certified in internal medicine and allergy/immunology, focuses on immune health and reducing toxic exposures. She discusses how chronic inflammation starts, gut microbiome disruption from microplastics and ultra-processed foods, and hidden toxins in skincare, plastics, and household products. Practical swaps and home strategies to lower exposure and support immune balance are highlighted in lively, actionable conversation.

Apr 16, 2026 • 42min
156. Dr. Judith Joseph: High-Functioning Depression, Anhedonia, and Reclaiming Joy
Dr. Judith Joseph, board-certified psychiatrist and author who studies high-functioning depression, explains how productive people can quietly lose joy. She explores anhedonia, how productivity masks distress, the biopsychosocial drivers of joy loss, and practical tools like the 5 Vs to restore daily points of pleasure.

Apr 14, 2026 • 55min
155. Dr. Eboni Cornish: Neural Longevity, Brain Inflammation, and the Hidden Root Causes of Mental Health Symptoms
Dr. Eboni Cornish, Associate Medical Director at Amen Clinics and expert in neuroinflammation and complex chronic illness, uses brain imaging to hunt hidden drivers of cognitive and mood symptoms. She discusses SPECT scans, how infections, toxins, hormones, and blood flow changes can mimic psychiatric conditions, the cerebellum’s broad role, and practical ways to restore cerebral perfusion for long-term brain resilience.

Apr 9, 2026 • 56min
154. Dr. Rick Doblin - Part 2: Psychedelics, MDMA Therapy, and the Future of Mental Health
Dr. Rick Doblin, founder and director of MAPS, leads global research into psychedelic-assisted therapies. Conversation covers how LSD, psilocybin, DMT, ayahuasca and MDMA shift perception and the default mode network. They explore therapy settings, integration, ketamine and ibogaine roles, and the politics, funding, and access shaping the future of mental health.


