Extend Podcast with Darshan Shah, MD
Darshan Shah, MD
Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health knowledge yields 80% of the results.
That's why this podcast is all about cutting through the noise on how to turn back the aging clock.
I interview world-renowned medical practitioners, doctors, experts, and thought leaders, offering you a step-by-step guide and actionable advice to proactively avoid disease and optimize your health.
Plus, I share weekly solo episodes giving you quick, digestible protocols for successfully extending your healthspan.
Episodes
Mentioned books
42 snips
Feb 26, 2026 • 1h 18min
142. Dr. Tommy Wood: The Science of Brain Performance Optimization
Dr. Tommy Wood, Associate Professor of Pediatrics and Neuroscience and performance scientist working with Formula One teams and dementia‑prevention groups. He explains the 3S model of Stimulus, Supply, and Support. Topics include how intense cognitive demand trains the brain, optimal learning cadence and focused work, sleep and nutrition for recovery, blood flow and blood pressure, and concussion prevention and nutrient support.
Feb 24, 2026 • 1h 9min
141. Dr. Amy Shah: Hormone Havoc, Gut Health, and the New Menopause Playbook
Dr. Amy Shah, double board‑certified physician, nutrition specialist, and author focused on midlife women’s health. She explores the gut microbiome’s role in estrogen metabolism, why fiber and fermented foods matter, and the 30g morning protein rule. They cover strength training, sprints, early DEXA scans, ferritin and vitamin D testing, and when targeted hormone therapy can be appropriate.
Feb 19, 2026 • 1h 28min
140. Dr. Kelly Casperson: The Hormone Truth About Women's Longevity
Dr. Kelly Casperson, a board-certified urologist, sex educator, and author helping women reclaim hormone and sexual health. She reframes aging as hormone and muscle loss. Topics include why estrogen, progesterone, and testosterone matter systemically. They debunk WHI misconceptions, explore vaginal estrogen, wearables and biomarkers, and discuss muscle, blood flow, exercise, and responsive desire.
13 snips
Feb 17, 2026 • 1h 24min
139. JJ Virgin: Muscle Over Weight Loss
JJ Virgin, triple‑board‑certified nutrition and fitness expert and NYT bestselling author, advocates a muscle‑first approach to metabolic health. She explains why focusing on weight harms metabolism. Short, practical segments cover simple strength tests, time‑efficient push/pull/hinge training, protein‑first nutrition, daily movement priorities, and safe GLP-1 use alongside resistance work.
Feb 12, 2026 • 1h 7min
138. Dr. Idrees Mughal: Why Most Viral Health Claims Fail
Dr Idrees Mughal, a UK-trained doctor and nutrition researcher known as Dr Idz, debunks viral health and nutrition claims with evidence-based clarity. He exposes cherry-picked studies, misuse of credentials, and the limits of animal or mechanistic research. Short, sharp conversations cover social media echo chambers, diet tribalism, sugars versus sweeteners, and when personal anecdotes mislead.
Feb 10, 2026 • 46min
137. Ariana Thacker: Mold Toxicity, Treatment Protocols + Genetic Susceptibility
Ariana Thacker, chemical engineer and CEO of MoldCo who rebuilt her life after toxic mold exposure. She explains mold as a systemic, cellular illness. Topics include how mold drives inflammation, hormone and mitochondrial disruption, genetic susceptibility, home dust testing, diagnostic pathways, and why treatment must pair medical care with environmental remediation.
Feb 5, 2026 • 1h 9min
136. Dr. Goodenowe: Plasmalogens and the Hidden Science of Longevity
Dr. Dayan Goodenowe, a neuroscientist and chemist who invented advanced metabolomics tools, explains the hidden role of plasmalogens in cellular membrane health. He discusses how falling plasmalogen levels predict dementia, cancer recurrence, and mortality years before symptoms. The conversation covers restoring membranes with precursors, tracking brain regrowth with advanced MRI, and prioritizing mental acuity, mobility, and mood.
Feb 3, 2026 • 1h 8min
135. Sarah Ann Macklin: Self-Compassion and Sustainable Behavior Change
Sarah Ann Macklin, a nutritionist and health educator who blends nutrition science with psychology, discusses how mindset, self-compassion, and neurodiversity shape sustainable health. She contrasts restriction-driven quick fixes with abundance-based habits. Conversations cover modeling industry pressures, food's impact on mental health, mindful food journaling, and practical tools to reduce stress and rebuild healthier routines.
10 snips
Jan 29, 2026 • 51min
134. Dr. Jessica Shepherd: Stop the Decline: Perimenopause Strategies
Dr. Jessica Shepherd, board-certified OB/GYN and midlife health expert, focuses on perimenopause and longevity. She discusses why conversations should start in the late 30s. She highlights resistance training as key, the role of hormone therapy for brain, bone, and metabolic health, the importance of early bone assessment, and simple functional tests and movements to preserve strength.
10 snips
Jan 27, 2026 • 1h 2min
133. Dr. Abid Husain: The Hidden Drivers of Heart Disease
Dr. Abid Husain, a cardiologist focused on cardiometabolic and regenerative approaches, explores hidden drivers of heart disease. He discusses microvascular dysfunction, the protective glycocalyx, and the importance of nitric oxide. Conversations cover clotting mechanisms, metabolic drivers like fatty liver and GLP-1 therapies, and the major role of chronic stress. Practical lifestyle and supplement strategies are also highlighted.
