The Jesse Chappus Show 691: Scientist Reveals Why Glycine Is Key to Turning Off Inflammation | Dr. Joel Brind
18 snips
Feb 10, 2026 
Joel Brind, Yale-trained life scientist who researches glycine and inflammation. He shares why he began high-dose glycine, rodent lifespan findings, how glycine targets methionine metabolism and immune cells, surprising self-experiment results where injuries did not inflame, practical dosing tips, and anecdotes on glycine’s effects for sleep, itch, gout, and COVID outcomes.
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Inflammation Is For Infection, Not Injury
- Inflammation is the immune system's first response to infection, not to injury.
- Joel Brind argues glycine prevents inappropriate inflammation after injury.
Supplement Glycine If Diet Lacks Bone Broth
- Supplement dietary glycine because modern diets lack it compared with historical nose-to-tail eating.
- Joel Brind began supplementing 10 g/day and believes most people need added glycine.
Self-Experiment: From 40 g To 10 g Daily
- Brind tested high-dose glycine in animals and then himself, starting with 40 g/day safely.
- He settled on 10 g/day mixed into gelatin and reported no adverse effects initially.
