The a16z Show
Andreessen Horowitz
The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
Episodes
Mentioned books
166 snips
Mar 2, 2026 • 60min
Chris Dixon: From Quant Trading to Building a16z Crypto
Chris Dixon, entrepreneur-turned-investor who built a16z’s crypto practice and backed Coinbase and Oculus. He traces his path from 1980s hobbyist programmer to quant trader to founder and VC. Conversation hits his framework for spotting ideas that scale, the mechanics of creating a crypto fund, the state of crypto regulation and stablecoins, and why New York is emerging as a tech hub.
461 snips
Feb 27, 2026 • 48min
a16z's New Media Playbook
Marc Andreessen, entrepreneur/investor and co-founder of Andreessen Horowitz, offers media theory and culture analysis. Ben Horowitz, co-founder and general partner at a16z, shares firm stories and strategy. They discuss speed and the OODA loop, why individuals matter more than corporate brands, flooding the zone with rapid messaging, oral versus written internet culture, and platform-native content tactics.
219 snips
Feb 26, 2026 • 47min
When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market
David George, general partner at Andreessen Horowitz who leads its growth fund, explains why roughly $5 trillion of tech value now sits private. He discusses why top companies delay IPOs, how private liquidity and tender offers affect employee pay, the rise of SPVs and cap table opacity, and whether AI’s rapid scale will push more firms toward public markets.
396 snips
Feb 23, 2026 • 1h 48min
Ben Horowitz: RSI, Crypto as AI Money, & Classified Physics
Ben Horowitz, cofounder and general partner at Andreessen Horowitz, offers sharp startup and tech strategy insight. He debates recursive self-improvement and whether AI can uncover new physics. He explains why crypto may serve as AI-native money and recounts his tense White House remark about regulating math and national security.
437 snips
Feb 20, 2026 • 53min
Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding
Patrick Collison, CEO of Stripe and former Smalltalk/Lisp tinkerer, reflects on early engineering choices and long-term trade-offs. He talks about interactive development environments, API and data-model decisions that shape organizations, using AI for coding and research, and applying foundation models to biology. Short, sharp conversations about tooling, runtime insights, and the future of programming.
488 snips
Feb 19, 2026 • 58min
AI’s Capital Flywheel: Models, Money, and the Future of Power
Sarah Wang, an a16z GP who backs frontier AI model teams, and Martin Casado, an a16z GP and infrastructure veteran, explore the current AI funding surge. They discuss why capital, compute, and rapid model gains make this cycle unique. They unpack blurred lines between apps and infrastructure, massive new round dynamics, talent wars, custom silicon economics, generative 3D, and two divergent industry futures.
404 snips
Feb 18, 2026 • 60min
From Copilots to Agents: Rebuilding the Company Around AI
Carlos García Ottati, founder and CEO of Kavak, built Latin America’s largest online used-car marketplace. He talks about constructing multiple businesses under one product, replacing copilots with AI agents to handle most customer interactions, and enduring a year of flat growth while rebuilding operations, culture, and infrastructure to scale across markets.
405 snips
Feb 17, 2026 • 31min
WSJ x a16z: The Next 25 Years of Defense Innovation
Katherine Boyle, general partner at Andreessen Horowitz who leads the American Dynamism practice investing in national security and defense tech. She discusses the 2022 cultural shift in Silicon Valley, how Ukraine and Starlink reshaped battlefield tech, the rise of mass-produced drones and attritable systems, and why reshoring supply chains and rebuilding the defense industrial base matter.
279 snips
Feb 16, 2026 • 58min
Novartis CEO Vasant Narasimhan on Transforming a 250-Year-Old Company
Vasant Narasimhan, physician-scientist and CEO who refocused Novartis into a pure-play medicines company, discusses platform bets in cell and gene therapy, RNA medicines, and radioligand therapies. He talks AI’s role across discovery and trials. He also covers global shifts in biotech, China’s rise, and what technical milestones and manufacturing work matter when partnering with startups.
351 snips
Feb 13, 2026 • 1h 4min
Balaji and Dan Wang: The Engineering State vs Lawyerly State
Dan Wang, technology analyst and author of Breakneck, explores China’s industrial rise and its political strains. He and Balaji compare manufacturing power to America’s software and finance strengths. They discuss migration of entrepreneurs, the durability of Bitcoin and protocols, and how both superpowers make self-sabotaging mistakes. The conversation sketches long, messy geopolitical competition and where builders might fit next.
