The Dr. Hyman Show

Dr. Mark Hyman
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May 13, 2026 • 1h 23min

Women Are Not Small Men! Why Fitness Advice Is Failing Half the Population | Dr. Stacy Sims

Dr. Stacy Sims, an exercise physiologist who studies sex differences in training and nutrition, explains why women are not small men. She discusses hormonal life stages, how metabolism and muscle change in your 30s and 40s, and why strength work and proper protein timing beat endless cardio. Practical tips include age-specific training, true high-intensity work, and circadian-friendly eating.
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21 snips
May 11, 2026 • 27min

The 5 Root Causes of Autoimmune Disease (And How to Start Healing)

They explore five root drivers of autoimmune problems: food, environmental toxins, gut health and microbiome, hidden infections, and stress. The conversation highlights diet shifts, elimination strategies, and gut-focused approaches. Practical starting steps for reducing inflammatory triggers and supporting immune balance are discussed.
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73 snips
May 6, 2026 • 1h 13min

The Real Reason You Age (And How to Slow It Down) | Dr. Eric Verdin

Dr. Eric Verdin, physician-scientist and CEO of the Buck Institute known for research on mitochondria and compounds like urolithin A, dives into why aging underlies major diseases. He discusses inflammation, immune aging, mitochondrial health, mitophagy, the microbiome’s role, and daily habits that shape longevity. Short, science-forward conversation about shifting from treating disease to targeting aging’s root causes.
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28 snips
May 4, 2026 • 27min

6 Root Causes of Migraines (And How to Fix Them)

Dr. Todd LePine, a functional medicine physician who treats complex migraine cases, joins to unpack migraine drivers. He explores gut and histamine links, blood sugar and nutrient gaps, hormonal and nervous system triggers. Short clinical stories and practical fixes pop up throughout, from dietary shifts to stress and caffeine strategies.
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59 snips
Apr 29, 2026 • 1h 5min

The Mental Health Crisis Starts in the Gut | Dr. William Li & Dr. Mark Hyman

Dr. William Li, physician-scientist and bestselling author known for work on nutrition and the microbiome, explores how the gut talks to the brain. Short takes cover the flavorome, polyphenols, fermented foods, and specific plant compounds that signal mood and memory. They also discuss processed-food harm, microbiome balance, and food-driven pathways that may support brain repair.
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58 snips
Apr 27, 2026 • 38min

Feeding Kids Is Hard—Here’s What They Actually Need

The conversation covers how modern food environments and ultra-processed foods challenge kids and parents. It highlights five nutritional anchors like protein, healthy fats, fiber, and blood sugar stability. Practical tips include clean snack ideas, ways to reduce processed foods, and how to influence school meals. They also discuss supplements to consider and connections between diet, gut health, and conditions like eczema.
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4 snips
Apr 22, 2026 • 1h 8min

We Can Detect Cancer Years Earlier—So Why Aren’t We?

Dr. Daniel K. Sodickson, physicist and imaging pioneer who helped advance MRI tech, explains why shifting from one‑time scans to tracking over time could catch disease earlier. He discusses using baseline MRIs, longitudinal imaging to cut false positives, AI plus prior data for faster cheaper scans, and how imaging complements blood tests for proactive health monitoring.
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80 snips
Apr 20, 2026 • 30min

Can’t Fall or Stay Asleep? Your Sleep Questions Answered

Explores why sleep problems are usually multi-factorial, not just habits. Covers circadian disruption, blood sugar swings, hormones, inflammation, and nervous system overdrive. Discusses nighttime awakenings, feeling tired after enough hours, and common hidden causes. Reviews which supplements and simple foundational habits can help you get more consistent, restorative sleep.
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16 snips
Apr 15, 2026 • 1h 22min

Tired But Wired? The Hidden Loop Destroying Your Energy | Dr. Scott Sherr, MD

Dr. Scott Sherr, a physician focused on mitochondrial health and nervous system regulation, lays out the 'sympathetic spiral of doom' that leaves people feeling tired but wired. He explores how chronic stress, mitochondrial dysfunction, medications and toxins trap energy and recovery. Practical approaches include rebuilding mitochondrial capacity, targeted testing, and strategic interventions like low‑dose methylene blue and calming supports.
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27 snips
Apr 13, 2026 • 20min

What It Really Means to Regulate Your Nervous System—and How to Start

Dr. Scott Scher, a clinician-researcher who studies stress physiology and mitochondrial function, walks through sympathetic activation and how it ties to mitochondrial dysfunction. He explains signs of nervous system dysregulation and contrasts “tired but wired” with true resilience. The conversation highlights practical science-backed ways to start regulating through breath, blood sugar, sleep, and daily habits.

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