This Week in Virology

Vincent returns to the Centre for Virus Research at the University of Glasgow and meets with postdocs to discuss their science and their careers. Links for this episode: MRC-University of Glasgow Centre for Virus Research Stop CMV Photos of my Glasgow visit (Facebook and VirusTalk) TWiV on Facebook

Hosts: Vincent Racaniello, Massimo Palmarini, John MacLauchlan, Emma Thomson, and Hande Harmanci. Vincent travels to Scotland to meet with members of the Centre for Virus Research at the University of Glasgow to discuss their work on hepatitis C virus and jaagsiekte sheep retrovirus. Links for this episode: MRC-University of Glasgow Centre for Virus Research Aaron Shatkin, 77 (virology blog) Photos of my Glasgow visit (Facebook and VirusTalk) TWiV on Facebook Letters read on TWiV 188 Weekly Science Picks Vincent - Microbe art Listener Pick of the Week Judi - Cell Imaging (Mac App Store)

Hosts: Vincent Racaniello and Rich Condit Vincent and Rich discuss recovery of a hepatitis B viral genome from a 16th century Korean mummy, and personal omics profiling of an individual over a 14 month period. Links for this episode: Tracing HBV to the 16th century (Hepatology) HBV on TWiV Precautions with ancient DNA (Science) Personal omics profile over 14 months (Cell) A geneticist's research turns personal (NY Times) Mike Snyder on Futures in Biotech The DASH diet TWiV on Facebook Letters read on TWiV 187 Weekly Science Picks Rich - The Checklist by Atul GawandeVincent - Artologica Listener Pick of the Week David - Cracking your genetic code (Nova)Josh - The nuclearization of biology is a threat to health and security (pdf) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit The TWiV chiefs tackle reader email about how to pronounce Buda, Texas, grinding tree stumps, and much more. Links for this episode: Detecting antibodies or antigens by ELISA Peter Wildy Prize Biosafety levels Baltimore classification at Viral Zone TWiV on Facebook Letters read on TWiV 186 Weekly Science Picks Alan - World Wide Lightning Location NetworkRich - Steve Jobs by Walter IsaacsonVincent - The Ocelloid Listener Pick of the Week lafrenchfille - whatshouldwecallgradschoolNeva - Antiviral drugs by Carl ZimmerSergio - APSnet Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Vincent visits with members of the Department of Microbiology and Immunology at Northwestern University School of Medicine to discuss their work on herpesviruses and parainfluenzaviruses. Links for this episode: Longnecker laboratory Herpesvirus deubiquitinase is neuroinvasive determinant (PLoS Path) Paramyxovirus HN structure (PNAS) TWiV on Facebook Letters read on TWiV 185 Weekly Science Picks Sarah - Breasts: A Natural and Unnatural History by Florence WilliamsAndrew - The Strangest Man by Graham FarmeloVincent - Gates Grand Challenges in Global Health awards Listener Pick of the Week Ed - Pursuit of Light (YouTube); MRC Biomedical Picture of the Day; It's okay to be smart Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Vincent, Rich, and Alan consider how to reform the scientific enterprise to make it more effective and robust. Links for this episode: Reforming science: Methodological and cultural reforms (Infect Immun) Reforming science: Structural reforms (Infect Immun) Sharp rise in retractions (NY Times) Vannevar Bush TWiV on Facebook Letters read on TWiV 184 Weekly Science Picks Alan - PubMed PubReMinerRich - Intentional Blindness (YouTube)Vincent - Vaccine infographic Listener Pick of the Week Ken - Wattpad Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Connor joins the TWiV team to discuss bats as hosts for major mammalian paramyxoviruses. Links for this episode: NIH response to Osterholm letter (pdf) Who's afraid of the big, bad bioterrorist? Bats host major mammalian paramyxoviruses (Nature Comm) TWiV on Facebook Letters read on TWiV 183 Weekly Science Picks Connor - Microbiology Twitter journal clubAlan - Where the Wild Types Are (YouTube)Rich - May 14th: Smallpox vaccination dayDickson - Searching for pore-fection (Science)Vincent - RRResearch Listener Pick of the Week Stephen - Every Major's Terrible (xkcd)

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Michael J. Imperiale Michael joins the TWiV crew to discuss the recently published influenza H5N1 transmission paper and how it was viewed by the NSABB. Links for this episode: About the NSABB The Kawaoka paper (Nature) Mutant flu paper published (Ed Yong) Osterholm letter (pdf) US policy for dual research of concern (pdf) TWiV on Facebook Letters read on TWiV 182 Weekly Science Picks Alan - 18th century shipping mappedRich - Brave New World by Aldous HuxleyVincent - Air France 447 (Telegraph) Listener Pick of the Week Josh - Vaccines course by Dr. Paul Offit

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions. Links for this episode: Cotia virus (J Virol) Human Orf virus exposures (MMWR) IRF3 protects agains prion infection (J Virol) A mad cow in America (virology blog) Human orf (pdf) Space shuttle flies outside my window (YouTube) TWiV on Facebook Letters read on TWiV 181 Weekly Science Picks Kathy - Astronomy Picture of the Day (especially this and this)Rich - Tom Lehrer Element Song (YouTube)Vincent - Albert B. Sabin Archives Listener Pick of the Week Mark - Netter's Infectious Diseases by Elaine C. Jong and Dennis L. StevensRichard - Germs, Genes & Civilization by David P. Clark

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich review association of an interferon-induced protein with severe influenza, and stabilization of HCV RNA by a microRNA. Links for this episode: IFITM3 and severe influenza (Nature) Genetics of flu susceptibiligy (EurekAlert!) Stabilization of HCV RNA by Ago2-miR-122 (PNAS) Clinical trial of anti-mIR-122 TWiV on Facebook Letters read on TWiV 180 Weekly Science Picks Alan - Micro Empire (Vimeo)Rich - Census of marine lifeVincent - Pinterest Listener Pick of the Week Mark - The Secret Life of Plankton (YouTube)