This Week in Virology

Hosts: Vincent Racaniello and Jon Yewdell Vincent and is joined by special guest Jon Yewdell to discuss solutions for ending the current crisis in American biomedical research. Links for this episode: How to succeed in science: Taking the plunge (Nat Rev Mol Cell Biol) How to succeed in science: Making discoveries (Nat Rev Mol Cell Biol) How to succeed in science (YouTube) Resources for graduate students and postdocs Science career cartoons by Alexander Dent Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Matt Frieman, and Kathy Spindler Vincent, Alan, Matt, and Kathy review the use of silk to stabilize antibiotics and a viral vaccine, and an impaired-fidelity vaccine against SARS coronavirus. Links for this episode: Silk stabilization of antibiotics and vaccines (PNAS) Impaired-fidelity coronavirus vaccine (Nature Medicine) Select agent status and SARS therapies (Spoonful of Medicine) Letters read on TWiV 207 Weekly Science Picks Matt - Virus-associated pyramids (slide #11)Alan - Similarities of wave behavior (YouTube)Kathy - The glass transitionVincent - US cattle country in uproar at virus lab plans (BBC) Listener Pick of the Week Ricardo - Blackawton bees and Science is for everyone (TED)Tony - Biophilia by Bjork Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Dickson Despommier, and Kathy Spindler Vincent, Alan, Dickson, and Kathy discuss how the innate immune response to viral infection influences the production of pluripotent stem cells, and the diverse mobilome of giant viruses. Links for this episode: Innate immunity and nuclear reprogramming (Cell) Viruses affect cell reprogramming (The Scientist) Cell-penetrating peptides (Trends Mol Med) Provirophages and transpovirons (PNAS) Organic Lake photo and map Letters read on TWiV 206 Weekly Science Picks Alan - Locust by Jeffery A. LockwoodDickson - Nikon Small World Contest 2012Kathy - Influenza EncyclopediaVincent - Dengue fever sweeps India (NY Times) Listener Pick of the Week Allison - Fred Guterl on The Daily Show Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv.

Hosts: Vincent Racaniello and Harmit Malik Vincent is joined by special guest Harmit Malik to discuss his work on the evolution of genetic conflict. Links for this episode: Harmit on YouTube Retroviruses and mammalian placentation (PNAS) Paleovirology (Curr Opin Virol) Evolution among AIM2-like receptors (J Exp Med) Poxvirus genomic accordions (Cell) Letters read on TWiV 205 Weekly Science Picks Vincent - Candidates' answers to science questions Listener Pick of the Week Steve - Mural of Henrietta Lacks story (Microsoft Silverlight required) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Matt Frieman, and Kathy Spindler Vincent, Alan, Matt and Kathy review isolation of a new coronavirus from two patients in the Middle East, and expansion of the enteric virome during simian AIDS. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Novel coronavirus (virology blog one, two) PCR assay for novel CoV (Eurosurveillance) Isolation of novel coronavirus (NEJM) SARS CoV now a select agent (Federal Register, pdf) My Sharona Pathogenic SIV infection associated with expansion of gut virome (Cell) Letters read on TWiV 204 Weekly Science Picks Alan - Map of the WindMatt - Dark Side of the Earth; Insensitive guide to thriving in your Ph.D.; Gary Vanerchuck (YouTube)Kathy - How much does a shadow weigh? and Slinky drop answerVincent - A Parasite's Parasites; All the cool kids are on arXiv Listener Pick of the Week Nissin - Jungle Jim (1948) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Mark Challberg Vincent and Rich meet up with Mark Challberg to talk about his scientific career studying viral DNA replication, and his transition to an NIH Program Officer. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Purification of vaccinia virus DNA polymerase (J Biol Chem) Adenovirus DNA replication in vitro (PNAS) Herpes simplex viral genes required for DNA synthesis (J Virol) Letters read on TWiV 203 Weekly Science Picks Rich - Mattel Hot Wheels Curiosity RoverVincent - Should H5N1 Moratorium End? Listener Pick of the Week Claudio - DIY lab equipment (Ars Technica) and DIY Bio Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, T. Jack Morris, James Van Etten, and Charles Wood Vincent travels to the University of Nebraska to meet with members of the Nebraska Center for Virology and discuss their work on algal viruses, plant viruses, HIV and Kaposi's sarcoma herpesvirus. Links for this episode: The Nebraska Center for Viology Behind the scenes at TWiV 202 TWiV on Facebook Weekly Science Picks Charles - Rhabdovirus associated with hemorrhagic fever (PLoS Path)Vincent - Bacteriophage graffiti (jpg) Listener Pick of the Week Bob - Remembering Penny PinneoJanet - Penn and Teller on vaccinations (YouTube) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich, and Kathy answer reader email about rabies, xenotransplantation, poliovirus, Ph.D. programs, mosquitoes, and much more. Links for this episode: Mattias Schnell Novel rhabdovirus from Africa (Plos Path) Milwaukee protocol (Wikipedia) How lethal is rabies virus? (virology blog) Issues with polio eradication (J Gen Virol) Vaccine-derived polioviruses (J Inf Dis) Global pandemics with Hidde Ploegh (Vimeo) Polio vs Bin Laden (Alan Dove) Letters read on TWiV 201 Weekly Science Picks Alan - Wallace OnlineRich - World Rabies DayKathy - Yo-yos in spaceDickson - The Art in ScienceVincent - The Podcasters Studio Listener Pick of the Week Wink - DuckDuckGoJosh - Introduction to Solid State Chemistry Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Elke Mühlberger, Paul Duprex, and Ron Corley Vincent, Alan, and Rich celebrate the 200th episode of TWiV by visiting the National Emerging Infectious Diseases Laboratories at Boston University Medical Center, where they meet with Elke, Paul, and Ron to talk about building and working in a BSL4 facility. Links for this episode: The NEIDL NEIDL goes public (BU Today) Biosafety levels (Wikipedia) Select agents (Wikipedia) NEIDL stalled (Boston Business J) TWiV on Facebook Letters read on TWiV 200 Weekly Science Picks Alan - Dance your Ph.D.Rich - Angel of Death by Gareth WilliamsVincent - Why herpesvirus is good for you (Virgin lab) Listener Pick of the Week Luis - VBORNET maps Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello and W. Ian Lipkin Vincent and Ian review a multicenter blinded analysis which finds no association between chronic fatigue syndrome/myalgic encephalomyelitis and XMRV or polytropic murine leukemia virus. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Multicenter blinded analysis of CFS and XMRV/pMLV (mBio) Press release on multicenter study (pdf) Press conference webcast TWiV on Facebook Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.