This Week in Virology

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler The Grand Masters of the TWiV discuss Ebola virus transmission, air travel from West Africa, Ebola virus infectivity on surfaces, the Dallas Ebola virus patient, and Ebola virus in dogs. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Science communications fellow at ASM CDC Ebola virus fact sheet (pdf) CDC Ebola virus infographic (pdf) No Reston virus replication in arthropods (Am J Trop Med Hyg) Inoculation of plants and animals with Ebola virus (Emerg Inf Dis) Arthropod studies during Ebola virus outbreak (J Inf Dis) Medbox: Ebola toolbox Facts about bushmeat and Ebola (pdf, CDC) Should US ban incoming flights from West Africa? Survey: should flights from Ebola countries be banned? (NBC News) Ebolavirus content at virology blog and TWiV Volunteer to help with the Ebola virus crisis Ebola and Anthropology webinar Asymptomatic Ebola virus infection (Lancet) Persistence of Ebola virus during 1995 outbreak (J Inf Dis) Assessment of Ebola virus transmission risk (J Inf Dis) Ebola virus transmission risk factors (Emerg Inf Dis) UV inactivation of Ebola virus (J Virol) Ebola virus persistence in darkness (Arch Virol) UV sensitivity of Ebola virus (Arch Virol) Treatment of Ebola virus infection with brincidofovir (virology blog) Ebola virus in domestic animals (Dev Biol) Ebola virus in dogs (Emerg Inf Dis) Ebola screening at US airports (CDC) Letters read on TWiV 306 Weekly Science Picks Alan - The Sixth Extinction by Elizabeth KolbertKathy - Seeing the InvisibleVincent - 2014 Scientific American Science in Action Award winner Listener Pick of the Week Mauricio - Investigating a mystery diseaseHeather - Diversity Journal ClubJohnye - Flu Attack! Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Science communications fellow at ASM Can we get AIDS from mosquito bites? (J La State Med Soc) Why mosquitoes cannot transmit AIDS Isolation of Bundibugyo ebolavirus in Uganda (PLoS Path) Ebola virus disease outbreak, Nigeria (MMWR) Nigeria contains Ebola virus outbreak (NY Times) First Ebola virus case in US (NY Times) Ebola virus disease: USA ex Liberia (ProMedMail) First imported Ebola virus case in US (CDC) Assessing risk of spread of Ebola virus (PLoS Currents) How contagious is Ebola virus? (NPR) Estimating reproductive index of Ebola virus (PLoS Currents) Polio-like illness, EV-D68 suspected (ProMedMail) Polio-like illness, North America (ProMedMail) Four deaths associated with EV-D68 (NY Times) Image credit: Pigott et al eLife Letters read on TWiV 305 Video of this episode - view at YouTube Weekly Science Picks Alan - Under the knife, episode 1Kathy - UCSC Ebola genome portalVincent - Annual Review of Virology, volume 1 Listener Pick of the Week Alan - H5N1Peter - Vomiting LarryDara - I just can't wait for my vaccine! Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Guest: Jeff Shaman The TWiV team consults an epidemiologist to forecast the future scope of the Ebola virus epidemic in West Africa. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Science communications fellow at ASM Estimating future cases in Ebola virus epidemic (MMWR) Columbia prediction of Ebola outbreak The Ebola emergency (NEJM) Q&As on Ebola virus transmission (CDC) Ebola virus transmission to monkeys (Lancet) Aerosol infection of monkeys with Ebola virus (Int J Exp Path) Ebola virus replication in pigs (J Inf Dis) Pathology of aerosol Ebola virus infection in rhesus macaques (Vet Path) Murine model of Ebolavirus infection (Viruses) Ebola virus transmission from pigs to non-human primates (Sci Rep) Transmission risks in BSL4 laboratory (Sci Rep) Why Ebola virus is unlikely to go airborne (Vox) Letters read on TWiV 304 Weekly Science Picks Alan - Fabre's Book of InsectsKathy - Origami microscope for 50 centsDickson - Landsat 8Vincent - Some advice from Jeff Bezos Listener Pick of the Week Justin - Brazil releases 'good' mosquitoes to fight dengue fever Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode 2014 Ebola virus outbreak at Healthmap Ebola virus transmission from bodily fluids and fomites (JID) Value of gain of function experiments (mBio) Rich Condit in the Washington Post on Ebola virus NPR on Ebola virus transmission What we are not afraid to say about Ebola virus (virology blog) Inhibition of Borna disease virus by an endogenous element (PNAS) Bornavirus at ViralZone Photo: Thirteen-lined ground squirrel (image credit) Letters read on TWiV 303 Weekly Science Picks Alan - PhotogrammarKathy - Refrigerate your tomatoes?Dickson - Robot swarmVincent - The Beginner's guide to winning the Nobel Prize by Peter Doherty Listener Pick of the Week Dee - Publish scientific research faster on TWiSTBasel - Lego microscope (vote for it) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68. Links for this episode Cancer patient saved by measles virus Ebola virus genome sequences (Science) Robert Garry on Ebola outbreak Aerosol transmission WHO Ebola outbreak summary CDC Ebola outbreak page Ebola outbreak epi curve CED Ebola outbreak info graphic Ebola response roadmap (CDC) Ebola outbreak discussion at ICAAC Human trial of Ebola virus vaccine (CNN) Chimpanzee adenovirus vectored Ebola virus vaccine (Nat Med) How US Ebola patients were cured (Sci Amer) Ebola outbreak could affect 20,000 (NY Times) Ebola infection control resources NLM free access to Ebola papers Science Ebola papers open access Gates donates money for Ebola outbreak (Wash Post) Smuggled bushmeat? (Newsweek) What we are not afraid to say about Ebola (NY Times) Enterovirus D68 outbreak (MMWR) Mark Pallansch on EV-D68 (NPR) Enterovirus D68 (CDC) EV-D68 isolation 1962 (Am J Ep) Outbreak of enterovirus 68 (virology blog) Letters read on TWiV 302 Weekly Science Picks Alan - Index to creationist claimsRich - Wild KrattsKathy - Worn awayDickson - Iceland volcano eruptionVincent - Immune Quest Listener Pick of the Week Kay - Landes Bioscience open access books Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Carla Saleh and Curtis Suttle At the International Congress of Virology in Montreal, Vincent speaks with Carla and Curtis about their work on RNA interference and antiviral defense in fruit flies, and viruses in the sea, the greatest biodiversity on Earth. Links for this episode Greatest biodiversity on Earth (Genome) Cafeteria roenbergensis virus (PNAS) Marine viruses (Nat Rev Micro) RNAi and reverse transcription is antiviral in flies (Nat Imm) Friendly persistent infections (Curr Op Micro) RNAi and antiviral defense in Drosophila (Dev Comp Imm) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent speaks with Dickson, Alan, Rich, and Kathy about their careers in science. Links for this episode So Happy Together (The Turtles) Viral Hemorrhagic Fever Consortium Support Kenema VHFC program Letters read on TWiV 298 Video of this episode - view at YouTube Weekly Science Picks Alan - The Internet's Original SinDickson - PlacidcoyoteRich - Scientific Method, Grail StyleKathy - Viruses Throughout Life and TimeVincent - ALS Ice Bucket Challenge Listener Pick of the Week Jim - iBiologyVictoria - Images of ScienceMehul/Walt - Calling the Shots Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Marshall Bloom, Sonja Best, and Byron Caughey Vincent visits the Rocky Mountain Laboratories in Hamilton, Montana and speaks with Marshall, Sonja, and Byron about their work on tick-born flaviviruses, innate immunity, and prion diseases. Links for this episode Rocky Mountain Laboratories, NIH Flavivirus persistence (Path Dis) Flaviviruses antagonize IRF1 (J Imm) Prion test using nasal brushings (NEJM) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiV gang answer follow-up questions about the Ebola virus outbreak in West Africa, then discuss treatment of disseminated multiple myeloma with oncolytic measles virus. Links for this episode Use of unregistered interventions for Ebola virus disease (WHO) Response to anthrax and H5N1 incidents (CDC) Remission of disseminated cancer after treatment with oncolytic measles virus (Mayo Clin Proc) New viruses for cancer therapy (Nat Rev Micro) Cattaneo on TWiV Image credit Letters read on TWiV 298 Weekly Science Picks Alan - WTF, Evolution?! by Mara GrunbaumRich - Cold Spring Harbor Oral History CollectionKathy - Inside insidesVincent - Going Viral (Rocky Mountain Ballet Theatre) Listener Pick of the Week Kim - Nobel Prize PodcastsJohnye - The Planet is FineJennie - Counter-Zombie Dominance Plan (pdf) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiVites present an all-ebolavirus episode, tackling virology, epidemiology, and approaches to prevention and cure that are in the pipeline. Links for this episode Risks and benefits of gain-of-function experiments (mBio) Scientists for Science US Policy for oversight of DURC (pdf) US framework for guiding H5N1 transmission expts (pdf) Extra oversight for H7N9 experiments (Science) TWiV 283: No Reston for the weary Is it Ebolavirus or Ebola virus? (virology blog) Ebola virus disease update (WHO) Ebola virus disease FAQ (WHO) Ebola hemorrhagic fever (CDC) Ebola virus disease: ecology meets economy (PLoS NTD) 2014 Ebola virus outbreak (J Gen Virol) 2014 Ebola virus outbreak (MMWR) If Ebola virus came to the US (Vox) Zaire ebolavirus in West Africa (interview with Tom Solomon) Why Ebola patients were brought to US (Wash Post) Experimental treatment and vaccines for Ebola (CDC) Aerosol transmission of Reston virus (Sci Rep) Ebola - A growing threat? (NEJM) On the cusp of Ebola vaccine (Know) Ebolavirus vaccines and antivirals (virology blog) Immune responses to Ebolavirus infection (Exp Rev Clin Imm) Antibody therapy for Ebola (Hum Vacc Immunother) Plant derived monoclonals protect macaques from Ebolavirus (PNAS) Anti-ebolavirus monoclonal cocktail (Sci Trans Med) ZMapp info sheet (pdf) ZMapp PR (pdf) High tech treatment for Ebola (ArsTechnica) ZMapp protects macaques (Sci Rep) Letters read on TWiV 297 Weekly Science Picks Alan - Historical perspective on Ebola (Tara C Smith)Rich - Tell the negative committee to shut up (Fanuel Muindi)Kathy - Art of Night (Vimeo)Vincent - Is Ebola virus going to kill me? (John Skylar) Listener Pick of the Week Peter - Dr. Michael Saag interview by Dr. Virginia CampbellDavid - PI Predictor (app, article, publication) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv