This Week in Virology

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contribute to alphavirus pathogenesis. Links for this episode IL10 modulation of Th17 cells during alphavirus pathogenesis (PNAS) Th17 cells involved in influenza mediated gut injury (J Exp Med) Helper T cells 2014-15 flu season (CDC) Key facts about flu & flu vaccine (CDC) Does the flu vaccine work? (Turbid plaque) Effectiveness of flu vaccine (virology blog) Image credit Letters read on TWiV 316 Weekly Science Picks Alan - It came from the pondRich - WanderersKathy - The Sense of Style by Steven PinkerVincent - Life in Our Phage World Listener Pick of the Week Fernando - Reality based? Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich and Kathy association of a virus with sea star melting disease, and the finding of a phycodnavirus in the oropharynx of humans with altered cognitive functions. Links for this episode National Influenza Immunization Week (CDC) Densovirus associated with sea star wasting disease (PNAS) A virus that melts sea stars (virology blog) Chlorovirus in human oropharynx (PNAS) Algal virus in humans (virology blog) Image credit Letters read on TWiV 315 Weekly Science Picks Alan - ReelLife Science 2014 WinnersRich - The Martian by Andy WeirKathy - Dance Your Ph.D. WinnerVincent - Time Person of the Year 2014 - The Ebola Fighters Listener Pick of the Week Ricardo - MiniPCREli - Let's outsmart Ebola together AND The Ebola virus explained Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Kartik Chandran, Ganjam Kalpana, and Margaret Kielian Vincent travels to Albert Einstein College of Medicine where he speaks with Kartik, Ganjam, and Margaret about their work on Ebolavirus entry, a tumor suppressor that binds the HIV-1 integrase, and the entry of togaviruses and flaviviruses into cells. Links for this episode Antibodies that protect against Sudan virus (ACS Chem Biol) Ebola virus entry requires NPC1 (EMBO J) A toggle switch for virus entry (Nat Comm) Imaging alphavirus exit (J Virol) Defects in HIV-1 unable to interact with INI1 (Retrovirol) Cell cycle arrest by INI1 (Mol Cell Biol) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich discuss how norovirus, an enteric virus, can replace the functions of the gut microbiome. Links for this episode Ebola virus update (WHO) Norovirus can replace functions of gut microbiome (Nature) Post-vaccinal distemper encephalitis (N Z Vet J) Novel sea otter poxvirus (J Wildl Dis) Poliovirus escapes antibodies (virology blog) CDC whistleblower saga (Sci Based Med) Snopes on CDC whistleblower Image credit Letters read on TWiV 313 Video of this episode - view at YouTube Weekly Science Picks Alan - RetrocomputingRich - Where is Rosetta?Vincent - Antares rocket explosion Listener Pick of the Week Simon - Relatively PrimeMark - Giant Microbes Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Ebola virus appropriations (White House) ASM Ebola FAQ Quarantine due to Ebola virus in semen (NPR) Enteric bacteria promote norovirus infection of B cells (Science) Norovirus emerges (Zimmer) Stephanie Karst on TWiV 134 Image credit Letters read on TWiV 312 Weekly Science Picks Alan - How Ebola airlifts workKathy - Fred Murphy's Foundations of VirologyRich - Pendulum waveDickson - Young DipteristsVincent - Microbes After Hours: Ebola and TWiV iPhone 6 case Listener Pick of the Week Alane - Health MapTodd - Formaldehyde in vaccines Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guests: Zhen Fu and Biao He Vincent visits the University of Georgia where he speaks with Zhen Fu and Biao He about their work on rabies virus and paramyxoviruses. Links for this episode Blood-brain permeability and rabies survival (Antiviral Res) Rabies induces blood-brain permeability (J Virol) Virus neutralizing antibodies in CNS of non-lethal rabies (PLoS Neg Trop Dis) RSV vaccine based on PIV5 (Vaccine) New mumps vaccine (J Virol) PIV5-based influenza virus vaccine (J Virol) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Glenn Rall Guest: Ann Skalka Vincent and Glenn meet up with Ann and talk about her long and productive career in virology, from biochemistry to bacteriophage lambda to retroviruses. Links for this episode Skalka laboratory Asilomar Conference on recombinant DNA Unexpected inheritance (PLoS Path) Viral sequences in vertebrate genomes (J Virol) Assembly of integrase multimers (J Biol Chem) Cell cycle and retrovirus integration (J Cell Bioch) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Guidelines for monitoring potentially infected persons (CDC) ASTMH meeting rejects attendees from Ebola countries (ScienceInsider) Defense Threat Reduction Agency call for Ebola virus proposals NSF calls for Ebola virus proposals Review of Ebola virus human-human transmission (CDC) How Firestone controlled Ebola virus (MMWR) Could Reston virus be a vaccine for Ebola virus? (virology blog) Letters read on TWiV 309 Weekly Science Picks Alan - CDC Influenza activity weekly mapsKathy - Going Deep with David ReesRich - Virology Special Issue: Giant VirusesDickson - Nikon Small World WinnersVincent - TWiM #90 and Republicans are not scientists Listener Pick of the Week Paul - Tricks and Tools of Great ScientistsYegor - Hardcore HistoryAmanda - Vaccine ingredients; Anti-vaxers damage; Minds of anti-vaxers Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Vincent Racaniello Guest: Tom Solomon Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor. Links for this episode World's biggest brain Tom's YouTube channel Sex, drugs, and emerging viruses (TedX) The Running Mad Professor Image credit: ClickLiverpool Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Guest: Tara C. Smith Tara Smith joins the TWiEBOVsters to discuss the Ebola virus outbreak in west Africa, spread of the disease to and within the US, transmission of the virus, and much more. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Science communications fellow at ASM Nation turns to science (New Yorker) CDC employees in West Africa (CDC) UN botched Ebola response (AP) Ebola czar (CNN) Ebola vaccine and budget cuts (HuffPo) Collins' ridiculous meme (NOT junk) How to quarantine against Ebola (Mukherjee) Ebola fear in Heartland (Tara Smith) Massive mutations in Ebola virus (PunditFact) Ebola airport screening (CDC) What is contact tracing? (video) (CDC) Inside MSF Ebola unit (YouTube) Ebola tech bulletin (DuPont) HAI controversies Letters read on TWiV 307 Weekly Science Picks Alan - Fall foliage mapKathy - Interviews with Peter Piot (one, two) and autobiographyVincent - The Ebola connection Listener Pick of the Week Brooke - N.B. Designs on EtsyVictor - SMBC Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv