

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

25 snips
Feb 11, 2025 • 40min
Timbaland's Blueprint: How to Lose 130 Pounds, Beat Addiction, and Change Your Life TODAY! : 1249
Timbaland, the legendary producer behind hits for Jay-Z and Beyoncé, shares his remarkable journey of overcoming addiction and losing 130 pounds. He reveals the powerful mindset shift that enabled his transformation and stresses that self-discipline trumps willpower. Timbaland opens up about the realities of opioid addiction, his clean recovery without rehab, and the importance of daily habits. He also emphasizes the role of vulnerability in healing, urging listeners to embrace their personal stories for growth.

240 snips
Feb 6, 2025 • 1h 2min
Gary Brecka: The SECRET Blood Marker That Could Save Your Life! (pt. 2) : 1248
In this engaging discussion, Gary Brecka, a human biologist and longevity expert, uncovers the critical role of methylation in health. He reveals how genetic factors like the MTHFR mutation can impact mental health issues such as anxiety and ADHD, stemming from nutrient deficiencies rather than just brain chemistry. Gary highlights the gut-brain connection, explains why many diets fail, and emphasizes the importance of the homocysteine marker for longevity. Discover simple lifestyle changes that can boost energy and reverse serious health challenges.

81 snips
Feb 5, 2025 • 37min
Gary Brecka: The World Is KILLING You—Use AI To Restore Testosterone, Energy & Longevity (Pt. 1) : 1247
Gary Brecka, a leading expert in human longevity and hormone optimization, uncovers the hidden crises affecting our health. He discusses the alarming drop in testosterone levels and how corporate greed and environmental toxins play a role. Brecka emphasizes the need for functional medicine and biohacking for optimal health. The impact of AI on personalized hormone therapy and longevity strategies is explored. Additionally, he reveals myths around cholesterol and heart disease, challenging mainstream medical narratives.

149 snips
Jan 30, 2025 • 1h 40min
Ancient Secrets THEY Hid from You (That Still Work Today!) – Lost Technology, The Pyramid Code, and Quantum Reality | Billy Carson (Harvard & MIT) & Elisabeth Carson : 1246
Billy Carson, a Harvard-certified expert in ancient civilizations, and Elisabeth Carson, a bestselling author and neuroscience researcher, dive into the mysteries of lost technologies and quantum reality. They explore the Great Pyramid as a potential energy generator and discuss ancient civilizations’ understanding of frequency and longevity. Their insights bridge ancient wisdom with modern biohacking, revealing how suppressed knowledge can redefine wellness. The couple shares emotional journeys, emphasizing resilience and the transformative power of trauma in personal growth.

120 snips
Jan 28, 2025 • 1h 28min
Stop Counting Calories! Diet Myths Exposed (And What to Do Instead) | Dr. Nick Norwitz : 1245
In this enlightening discussion, Dr. Nick Norwitz, a metabolic health expert with a PhD from Oxford and an MD from Harvard, debunks the myth of calorie counting in weight loss. He reveals that metabolism is far more complex than the traditional 'eat less, move more' approach. Dr. Norwitz discusses the healing powers of ketosis and fasting, the importance of gut health, and even the surprising links between viruses and food addiction. This episode is a treasure trove of insights on personalized nutrition for optimal health!

76 snips
Jan 23, 2025 • 1h 35min
How to Hack Your Stress and Engineer Your Tears to BOOST Longevity | Jeff Krasno : 1244
Jeff Krasno, founder of Commune and author of "Good Stress," discusses the surprising benefits of mastering stress rather than avoiding it. He reveals how crying is a powerful emotional biohack that regulates stress and encourages resilience. Krasno explains the difference between good and bad stress, emphasizing that discomfort can lead to growth. He also explores the science behind emotional regulation and the importance of community connections for health, urging listeners to embrace moments of struggle to enhance their longevity.

312 snips
Jan 21, 2025 • 1h 29min
2025 Biohacking State of the Union: Master Supplementation Guide with Dr. Sandra Kaufmann : 1243
Dr. Sandra Kaufmann, a longevity expert and former pediatric anesthesiologist, joins the discussion with insights on practical anti-aging strategies. She challenges dietary norms by suggesting that indulging in 'bad' habits can coexist with longevity. The conversation highlights her Seven Tenets of Aging and dives into the science of sleep, mitochondrial health, and personalized supplementation. With humor mixed in, they tackle topics from cancer treatment to cognitive function, all while empowering listeners to take control of their health in a sustainable way.

154 snips
Jan 16, 2025 • 1h 7min
How to Be a Real-Life DR. STRANGE with These 8 Ancient Secrets for Healing | Barry Morguelan : 1242
Dr. Barry Morguelan, a renowned surgeon and grandmaster of an ancient Lao Tzu lineage, shares transformative secrets for healing and energy mastery. He reveals the 'Great 8' framework—timeless principles that can unlock your potential across various life aspects. The discussion delves into how quantum physics intertwines with ancient practices to promote health and reverse aging. With incredible personal anecdotes, Morguelan invites listeners to explore self-healing and the profound impact of energy techniques on their lives.

205 snips
Jan 14, 2025 • 1h 20min
Add Decades to Your Life with THESE AI Tools and Longevity Secrets! Peter Diamandis : 1241
In this insightful conversation, Peter Diamandis, a futurist and innovator known for his work with XPRIZE and the Abundance 360 community, explores groundbreaking strategies for extending healthspan. Peter highlights revolutionary AI tools transforming health, the crucial link between mindset and longevity, and shares practical daily habits to enhance energy and sleep. He delves into the science of biohacking, the importance of sleep optimization, and even the potential of gene editing technologies. Tune in for a treasure trove of tips to boost your vitality!

242 snips
Jan 9, 2025 • 58min
Improve your Vision Forever with These Three FREE Exercises | Dr. Bryce Appelbaum : 1240
Dr. Bryce Appelbaum, a visionary in vision biohacking, discusses transformative techniques to enhance eyesight and brain performance. He reveals simple 10-minute exercises that may help you ditch your glasses for good. The conversation covers the link between eyesight and cognitive health, the importance of outdoor activities, and how vision training can counteract issues like ADHD symptoms. With his own story of overcoming visual challenges, Dr. Appelbaum emphasizes that anyone can improve their vision with consistent practice and the right tools.


