

The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.This isn’t just self-improvement - it’s human enhancement backed by data.Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.
Episodes
Mentioned books

Apr 7, 2015 • 36min
David Waknine: Adversity, Filming A Documentary & Weight Loss - #209
Why you should listen –
David Waknine comes on Bulletproof Radio today to discuss what its like to get back in the ring, fighting through adversity, filming his new documentary, training and injuries. Enjoy the show!
David Waknine is the founder of Hollywood Fight Club Productions and Pinocchio’s Playhouse. He is a former boxer and one of the finalists in the Golden Gloves Boxing tournament. He has written and directed over 150 plays, commercials, and short films. He is currently the director and star of his upcoming documentary, One More Round, a documentary about a journey of a former Golden Gloves finalist returning to the ring and challenges he faces like injury, and weight loss.
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4 snips
Apr 3, 2015 • 1h 3min
Daniel Pardi: Date Rape Drugs, Napping, & Jet Lag - #208
Why you should listen –
Daniel Pardi comes on Bulletproof Radio today to discuss jet lag, sleep disorders like insomnia and narcolepsy, date rape drugs and the science of napping. Enjoy the show!
Daniel Pardi is a researcher in Psychiatry and Behavioral Sciences. He developed the Loop Model to Sustain Health Behaviors and created humanOS.me and dansplan.com to educate people on how to facilitate optimal health behaviors. He has consulted with the Naval Special Warfare department on how to make fighters more vigilant in combat and non-combat conditions, and has given keynote addresses at events like Paleo f(x).
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Mar 31, 2015 • 42min
Bulletproof Radio Q&A - #207
Why you should listen –
On this episode of Bulletproof Radio, we have carefully selected the best questions from Facebook, Twitter, and the Bulletproof® Forums for another awesome Q&A. Hear Dave answer questions with Zak about Diet Coke, moldy homes, nootropics and a lot of other great questions that our listeners have submitted to Bulletproof Radio. This episode has a ton of great information all condensed into one, enjoy!
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Mar 27, 2015 • 47min
Dr. Tami Mergalia: Testosterone Supplementation, Skinny Fat, & Adrenal Fatigue - #206
Dr. Tami Mergalia is a double board certified physician in Aesthetic Medicine, Integrative & Natural Medicine, and the owner of Vitality Medical Clinic in Seattle. She is a faculty member of the American Academy of Aesthetic Medicine and a national trainer in Medicis. She has travelled the world as a trainer in advanced injection techniques and lecturing on aesthetics and bioidentical hormones for men and women. She has been featured in Shape Magazine, Fox News and her new book, The Hormone Secret, lays out the secret weapons for anti aging, weight loss, and increased vitality.
Why you should listen –
Dr. Tami Mergalia comes on Bulletproof Radio to discuss adrenal fatigue, the importance of your circadian rhythm, what it means to be skinny fat, and the pros and cons of testosterone supplementation. Enjoy the show!
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Mar 24, 2015 • 45min
Wendy Myers: Heavy Metal Toxicity, Mineral Power, & Coffee Enemas – #205
Wendy Myers is the Founder and Chief Eating Officer of the Liveto110 Blog and host of the Liveto110 podcast show. She is a certified holistic health and nutrition coach, a functional diagnostic nutritionist, and creator of Mineral Power program that utilizes hair mineral analysis to help clients fix mineral deficiencies for a broad spectrum of health conditions. She specializes in using alternative detoxification treatments and diet to help people live healthier lifestyles and is currently working on her next book, The Modern Paleo Survival Guide.
Why you should listen –
Wendy comes on Bulletproof Radio to discuss how to detox heavy metals, hair mineral test analysis, coffee enemas, and living to 110. Enjoy the show!
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Mar 20, 2015 • 59min
Rocco Dispirito: Cook Your Butt Off - #204
Rocco Dispirito is a James Beard award-winning chef and author of eleven books, including the New York Times Best-selling Now Eat This!, The Pound a Day Diet, and his newest book, Cook Your Butt Off. He was named Food & Wine’s Best New Chef, was the first chef to grace the cover of Gourmet as “America’s Most Exciting Young Chef”, and opened the 3-star Union Pacific Restaurant in New York City.
Why you should listen –
Rocco comes on Bulletproof Radio to discuss modern cooking, food cravings, activity tracking in the kitchen, and why food should do more than just taste good. Enjoy the show!
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Mar 17, 2015 • 57min
Marc Goodman: Cyber Security, Transhumanism, & Future Crimes - #203
Why you should listen – Marc comes on Bulletproof Radio to discuss transhumanism, the dangers of technology, cyber security precautions you can take to protect yourself from cyber threats and cyber crime, and the story behind The Silk Road. Enjoy the show!
Marc Goodman is the founder of the Future Crimes Institute and currently serves as the Chair for Policy, Law and Ethics at the Silicon Valley’s Singularity University. Over the past 20 years, Marc has worked with Interpol, the United Nations’ Counterterrorism Task Force, NATO, and the US Government as a global strategist and consultant about the impact of technology on security, business, and international affairs. He has also worked as a police officer and undercover investigator, and has been published in business and technology publications such as The Economist, the Harvard Business Review, and Forbes, and been featured on a myriad of news networks, including CNN, ABC, NBC, BBC, and Fox News.
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Mar 13, 2015 • 1h 2min
Tom Malterre: Gluten, the Gut Microbiome, & the Elimination Diet - #202
Tom Malterre, a seasoned Functional Medicine Nutritionist and gluten-free cookbook co-author, dives into the addictive nature of gluten and dairy, likening them to opium. He discusses how elimination diets can effectively address these cravings and inflammation. The conversation also covers the gut microbiome's critical role in health, the effects of agricultural chemicals on gut diversity, and the health benefits of raw versus cooked cruciferous vegetables. Malterre emphasizes personal dietary approaches for enhanced well-being.

Mar 10, 2015 • 51min
Jen Wittman: Thyroid, PTSD, & Medicinal Cannabis - #201
Jen Wittman is a Certified Holistic Health Expert & Coach specializing in practical solutions for those suffering from thyroid and autoimmune conditions. She provides one-of-a-kind, long-lasting health overhauls at her sites, Thyroid Loving Care, The Healthy Plate, and Your Best Thyroid Life. She is author of the book: Healing Hashimoto's Naturally and the popular guides: The Super-Mom's Guide to Managing Thyroid Disease and The Partner's Guide to Thyroid & Autoimmune.
Why you should listen –
Jen comes on Bulletproof Radio to discuss the relationship between PTSD and food, how to manage Hashimoto’s Thyroiditis, the misdiagnosis of autoimmune diseases, and the therapeutic use of CBD oil and cannabis. Enjoy the show!
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Mar 4, 2015 • 1h 45min
Rick Doblin: Psychedelic Healing with Marijuana, MDMA, Psilocybin, & Ayahuasca - #200
Rick Doblin, the Founder of MAPS, dives into the world of psychedelic healing, drawing on his extensive background in public policy and therapy. He highlights the transformative power of psychedelics like psilocybin, MDMA, and ayahuasca when used in safe settings. Rick discusses the importance of intentionality and integration in healing experiences, the role of cannabis in treating PTSD, and innovative approaches to addiction treatment. Plus, he addresses the need for informed use and harm reduction strategies in recreational contexts.


