Mayo Clinic Talks

Host: Darryl S. Chutka, M.D.  Guest: Bhanu Kolla, M.D.  We commonly take sleep for granted. That is, until our sleep quantity or quality is compromised. This can result in both mental and physical health problems, including daytime fatigue and sleepiness. Sleep disorders are quite common and often undiagnosed, yet they can contribute to diabetes, cognitive impairment, and cardiovascular disease, potentially leading to premature mortality. Primary care clinicians play a major role in the identification and management of sleep disorders. What are the most common disorders we see in the outpatient setting? What are the presenting symptoms we should watch for? What tests should we do to establish a diagnosis and when should we refer patients we feel may have a sleep disorder? The topic for today’s podcast is sleep disorders, and these are questions I’ll be asking my guest, Dr. Bhanu Kolla, a psychiatrist and sleep medicine specialist from the Center for Sleep Medicine at the Mayo Clinic.   This episode of Mayo Clinic Talks is the first of three podcasts celebrating a remarkable milestone in Mayo Clinic’s history – the 100th anniversary in April this year of our renowned journal, Mayo Clinic Proceedings. Proceedings first appeared in April 1926 and has been in continuous publication ever since. Many significant clinical breakthroughs, pioneered at Mayo Clinic, were first published in the journal, and today the journal brings primary care providers relevant, timely, and important papers on conditions and disorders that are frequently seen in the practice. A great deal of content in Mayo Clinic Proceedings is freely available for you to browse—just go to mayoclinicproceedings.org to incorporate this terrific resource in your library. Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Brittni A. Scruggs, an ophthalmologist and retinal surgeon who treats adults and children and works on gene therapy, joins to discuss retinal disorders. She covers common conditions to watch for in primary care. She highlights retinal vascular occlusions, detachment risks, diabetic retinopathy screening, age-related macular degeneration, medications that affect the retina, and emerging gene and dry AMD therapies.

Stephen Kopecky, a preventive cardiologist at the Mayo Clinic, discusses modern hyperlipidemia care. He covers combination therapy to safely lower LDL. He explains lower LDL targets for prevention and disease. He reviews new risk markers, PCSK9 therapies including inclisiran, coronary calcium scoring, Lp(a) testing, triglyceride strategies, and ways to improve adherence.

Host: Darryl S. Chutka, M.D.  Guest: Kathryn del Valle, M.D.  Chronic liver disease can result in a variety of complications which can involve multiple organs. One of these complications can occur in the pulmonary vascular system. Two of the most clinically significant include hepatopulmonary syndrome and Portopulmonary hypertension. Patients with these syndromes may present to their primary care provider and if the medical condition is unrecognized, it can affect morbidity and ultimately the prognosis of the patient. What are the early symptoms and physical findings of hepatopulmonary syndrome and Portopulmonary hypertension? How are they diagnosed, and should we be screening patients with chronic liver disease for these pulmonary vascular disorders? My guest for this podcast is Dr. Kathryn del Valle, from the Division of Pulmonary and Critical Care at the Mayo Clinic and we’ll be discussing “Pulmonary Vascular Complications of Liver Disease”.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Host: Darryl S. Chutka, M.D.  Guest: Stephen Ansell, M.D., Ph.D.  Non-Hodgkin’s Lymphoma is a group of hematologic malignancies originating in the lymphatic system. There are over 60 subtypes of lymphoma with varying degrees of aggressiveness. It can present with a variety of rather subtle symptoms, often making the diagnosis challenging. Although Non-Hodgkin’s Lymphoma is typically managed by a hematologist or oncologist, the primary care provider plays a role in its recognition, preliminary diagnostic tests and supporting patients through their treatment. What are some of the more common symptoms and signs of Non-Hodgkin’s Lymphoma? Which ones should prompt an urgent referral, and what preliminary tests should we do prior to referring the patient? These are some of the questions I’ll be asking my guest, Dr. Stephen Ansell, Chair of the Division of Hematology at the Mayo Clinic. The topic for this podcast is Non-Hodgkin’s Lymphoma.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Host: Darryl S. Chutka, M.D.  Guest: Stephen Ansell, M.D., Ph.D.  Hodgkin’s Lymphoma is an uncommon but very curable malignancy involving the lymphatic system. It most commonly presents in young adults as well as middle-aged and older individuals. Although Hodgkin’s is generally managed by hematologists or oncologists, the primary care provider plays a major role in its recognition, hopefully leading to a timely diagnosis and eventual staging. What are some early signs of Hodgkin’s and what preliminary work-up should we do prior to referring the patient for definitive care? How do we monitor those who have had successful treatment of Hodgkin’s? These are some of the questions I’ll be asking my guest, Dr. Stephen Ansell, Chair of the Division of Hematology at the Mayo Clinic as we discuss Hodgkin’s Lymphoma.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Host: Darryl S. Chutka, M.D.  Guests: Jae K. Oh, M.D., Tahir S. Kafil, M.D.  Diastolic heart failure is also known as heart failure with preserved ejection fraction. Although we don’t hear the term all that often, it actually represents a fairly large percentage of all cases of heart failure. Some studies suggest it represents the majority of heart failure cases. Older adults are most commonly affected with symptoms similar to those of systolic heart failure. So how do we suspect diastolic heart failure? How should the diagnosis be established, and how does the treatment differ from systolic heart failure? Finally, what role do primary care providers play in the management of the condition? These are some of the questions I’ll be asking my guests, Dr. Jae Oh and Dr. Tahir Kafil, both cardiologists in the Department of Cardiovascular Disease at the Mayo Clinic as we discuss “Diastolic Heart Failure”.   Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Balaji Tamarappoo, cardiologist and cardio-oncology expert, outlines how cancer treatments can harm the heart. He highlights which therapies carry highest cardiac risk. He reviews baseline testing and surveillance strategies. He describes clinical signs that demand urgent evaluation. He stresses teamwork between primary care, oncology, and cardiology and the role of prevention in survivorship.

Host: Darryl S. Chutka, M.D.  Guest: Hema Narayanasamy, M.B.B.S.  Pericardial disease represents a spectrum of both inflammatory and non-inflammatory disorders which involve the pericardium, with acute pericarditis being the most common disorder. Although not often seen in a primary care practice, we still need to consider pericarditis as it can masquerade several other more commonly seen conditions. It’s important to recognize pericardial disease early and decide who needs an urgent referral or hospitalization for appropriate treatment. What are some of the more common causes of pericardial disease? What are the most commonly encountered symptoms, physical exam findings, imaging results, and lab abnormalities? What are the potential complications? The topic for today’s podcast is pericardial disease, and my guest is Dr. Hema Narayanasamy, from the Department of Cardiovascular Disease from the Arizona campus of the Mayo Clinic.  Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 

Host: Darryl S. Chutka, M.D.  Guest: Stephen Kopecky, M.D.  We have a variety of pharmacologic options and lifestyle changes we recommend to our patients to reduce their cardiovascular risks. One frequent recommendation is participation in a regular exercise program. One specific type of exercise is high intensity interval training. It’s been shown to improve a variety of metabolic parameters. What does high intensity interval training consist of? What are the specific metabolic benefits? Can all patients participate in this type of exercise? What’s the recommended duration and frequency of training and how good is patient adherence to interval training? The topic for this podcast is “High Intensity Interval Training and Reducing Cardiovascular Risk” and my guest is Dr. Stephen Kopecky, a preventive cardiologist in the Department of Cardiovascular Disease at the Mayo Clinic.  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development