Mayo Clinic Talks

Mayo Clinic
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Feb 5, 2026 • 29min

Heart Health Series | Bicuspid Aortic Valve Disease

George Wang, cardiologist specializing in valvular disease and aortic pathology, discusses bicuspid aortic valve disease and related aortopathy. He covers genetics and valve shapes. He reviews how and when the condition is found, imaging and surveillance strategies, medical control of risk factors, surgical thresholds, and lifestyle considerations like exercise and pregnancy.
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Feb 3, 2026 • 30min

Heart Health Series | Cardiac Amyloidosis

Host: Darryl S. Chutka, M.D.  Guest: Julie Rosenthal, M.D.  Cardiac amyloidosis is not a common condition, but it is important for primary care clinicians to recognize it in our patients. It’s commonly underdiagnosed as the symptoms are often assumed to be due to other, more common cardiac problems. Early recognition is important since this can result in improved treatment options and better patient outcomes. So how do we recognize cardiac amyloidosis? What are the presenting symptoms and what’s the best way to establish an accurate diagnosis? I’ll be asking my guest these questions as we discuss cardiac amyloidosis. My guest for tis podcast is Dr. Julie Rosenthal, a cardiologist in the Department of Cardiovascular Medicine at the Arizona campus of the Mayo Clinic.   Mayo Clinic Talks: Heart Health | Mayo Clinic School of Continuous Professional Development  Connect with us! Mayo Clinic Talks Podcast Season 6 | Mayo Clinic School of Continuous Professional Development 
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Jan 27, 2026 • 28min

Concussions: What Every Primary Care Provider Should Know

Matthew B. Anastasi, a family and sports medicine physician at Mayo Clinic Arizona, explains concussion basics and who to worry about. He covers how to recognize symptoms, red flags that need imaging, early management and stepwise return to activity. Special considerations for children, older adults, repeat injuries and prevention are highlighted.
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Jan 20, 2026 • 20min

Rx for Weight Loss: A Closer Look Series "The Wins of Losing: GLP-1 Agonists and Reducing Heart Disease Risk"

Host: Darryl S. Chutka, M.D.  Guest: Stephen Kopecky, M.D.  One of the biggest surprises we’ve seen in medicine in the past several years has been the numerous health benefits realized from the GLP-1 agonists. Originally developed for the management of diabetes, they’ve shown significant potential to improve cardiovascular risks, beyond controlling blood glucose and lowering hemoglobin A1c. Several studies have shown reductions in cardiovascular events including MI, stroke as well as reducing overall cardiovascular death. What is the mechanism of action for these cardiovascular benefits? Are there any differences in the various GLP-1 medications available and who’s a candidate for a GLP-1 medication? I’ll get answers to all of these questions and more in this podcast as I speak with Dr. Stephen Kopecky, a preventive cardiologist at the Mayo Clinic. We’ll be discussing “GLP-1 Agonists and Reducing Cardiovascular Risk”.  Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development  Learn more at https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts
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Jan 15, 2026 • 24min

Rx for Weight Loss: A Closer Look Series "Controversies & Future of GLP-1 Medications"

Host: Darryl S. Chutka, M.D.  Guests: Tamim I. Rajjo, M.D., M.P.H.; Meera Shah, M.B., Ch.B.  The class of medications known as the GLP-1 agonists is very popular with our patients. Although initially indicated for management of diabetes, they’re frequently taken for the weight loss they commonly produce. How long should these medications be taken? Is there anything we can do to help maintain the weight loss achieved with these medications? How significant is the loss of muscle mass which can occur as part of the weight lost with these medications and can this be minimized. Finally, how safe are the compounded and unapproved versions of these medications patients often find more affordable? These are a few of the questions we’ll address in podcast on the GLP-1 medications used for weight loss and we’ll tackle the “Controversies and Future of the GLP-1 Medications”. My guests include Dr. Meera Shah and Dr. Tamim Rajjo, both from the Division of Endocrinology at the Mayo Clinic.  Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development  Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 
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8 snips
Jan 13, 2026 • 26min

Rx for Weight Loss: A Closer Look Series "Importance of Lifestyle Changes with Use of GLP-1 Medications"

Host: Darryl S. Chutka, M.D.  Guest: Tamim Rajjo, M.D., M.P.H.  Using GLP-1 medication for weight loss has become very popular with our patients. In the recent past, this has produced a shortage of these medications available, and those taking them for management of diabetes have found them difficult to obtain. Although in most cases, they are quite successful in producing substantial weight loss, many have regained weight after the medication was discontinued. How much weight can patients expect to lose with these medications? When should these medications be stopped, or should they? Are there strategies that have shown benefit to help patients maintain the weight they lose once the medication is discontinued? This podcast is the second of three on using the GLP-1 medications for weight loss and we’ll discuss “The Importance of Lifestyle Changes with the Use of GLP-1 Medications for Weight Loss”. My guest is Dr. Tamim Rajjo, a physician trained in Preventive Medicine and Obesity Medicine from the Mayo Clinic.  Rx for Weight Loss: A Closer Look Series | Mayo Clinic School of Continuous Professional Development  Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 
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7 snips
Jan 8, 2026 • 26min

Rx for Weight Loss: A Closer Look Series “Who is a Candidate for a GLP-1 Medication?”

In this engaging discussion, endocrinologist Dr. Meera Shah and obesity medicine expert Dr. Tamim I. Rajjo delve into the promising world of GLP-1 medications for weight loss. They cover the history and FDA approval milestones of these drugs, as well as their physiological impacts on appetite and caloric intake. The guests thoughtfully discuss who qualifies for GLP-1 therapy, the importance of tailoring treatments based on individual health factors, and potential side effects to watch out for, providing valuable insights for anyone interested in obesity management.
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16 snips
Jan 6, 2026 • 24min

The Risks and Benefits of Alcohol

Warren G. Thompson, an internist and preventive medicine specialist at the Mayo Clinic, dives into the complex world of alcohol consumption. He explores common misconceptions about drink sizes and the real health benefits that might apply to those over 40. The discussion highlights the blurry line between moderate drinking and health risks, including cardiovascular issues and increased cancer risks. Thompson also warns against using alcohol for mental health relief and stresses tailored advice for different age groups. Practical takeaways include keeping to one drink a day with food.
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9 snips
Dec 30, 2025 • 30min

Re-Release!! "No Loafing Matter" Celiac Disease & Gluten Sensitivity

HAPPY HOLIDAYS! Enjoy this re-release from Season 3 of Mayo Clinic Talks: Host: Darryl S. Chutka, M.D.  Guest: Amy S. Oxentenko, M.D.   It’s estimated that less than 1/3 of individuals with celiac disease have been properly diagnosed. When those with celiac disease ingest gluten, an immune response develops which attacks the small intestine leading to inadequate absorption of nutrients. If left untreated, celiac disease can lead to a variety of nutritional deficiencies as well as other serious consequences. Those with celiac disease are also at increased risk for coronary disease and small bowel cancers. In this podcast we’ll review celiac disease and gluten sensitivity with our guest, Amy S. Oxentenko, M.D., a gastroenterologist at the Mayo Clinic. We’ll discuss the symptoms of celiac disease, how to diagnose the condition and how patients with celiac disease should be managed.   Connect with us and learn more here: https://ce.mayo.edu/online-education/content/mayo-clinic-podcasts 
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Dec 23, 2025 • 26min

Re-Release!! "Lettuce Eat" Plant-Based Diets: Healthy and NonHealthy

Lisa Lammert, a registered dietitian specializing in plant-based nutrition, shares valuable insights on the benefits and challenges of plant-based diets. She discusses how these diets can reduce risk factors for heart disease, obesity, and diabetes, while also addressing the nutritional pitfalls of processed vegan foods. Lammert emphasizes the importance of fiber for gut health and offers practical tips for transitioning to plant-based meals. She also highlights key nutrients like protein, vitamin B12, and calcium, ensuring listeners understand how to maintain a balanced diet.

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