JAMA Editors' Summary

Editor's Summary by Linda Brubaker, MD, Preeti Malani, MD, MSJ, Deputy Editors of JAMA, and Gregory Curfman, MD, Executive Editor of the Journal of the American Medical Association, for articles published from March 28-April 3, 2026. Related Content: Audio Highlights

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from March 21-27, 2026.

Discussion of a trial showing no survival benefit and more harm from routine tumor debulking in metastatic colorectal cancer. A randomized ICU study comparing low versus high use of physical restraints and implications for individualized restraint practice. Analysis of declining insulin out-of-pocket costs for Medicare Part D enrollees after policy changes. Brief takes on FDA transparency, AI in residency applications, and US life expectancy debates.

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from March 7-13, 2026.

A trial testing personalized antidepressant selection and its impact on early treatment persistence. Rising rates of insufficient and very-short sleep among U.S. high school students. State-level mismatches between rural health funding, mortality, and population. Discussion of how physicians' roles may shift as artificial intelligence becomes more prominent.

Global differences in radiation doses from cardiac imaging and rising trends in donation after circulatory death. Shifts in newborn hepatitis B vaccination rates and evolving U.S. organ donation policies. New reimbursement ideas to align care with population health. Debates over SNAP restrictions and practical bedside approaches to assess intravascular volume overload.

They compare whole brain vs stereotactic radiation and highlight effects on symptoms and quality of life. Medicare trends get attention, including rising forced disenrollment and a new billing add-on code. Clinical updates cover pertussis in adults, microplastics for patients, and a comprehensive review of type 1 diabetes and individualized therapy approaches.

A roundup of recent medical research and policy updates. Topics include caffeine linked to lower dementia risk, performance of smartwatch alerts for hypertension, and aluminum exposure from diet and vaccines. Also covered: comparisons of IVF approaches, emergency department treatments for opioid use disorder, and ethical and regulatory debates about pregnancy trials and medical AI.

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from January 31-February 6, 2026.

A tour of cutting-edge transplant techniques and ethical questions around donation. Projections of rising U.S. obesity and persistent disparities. Trials testing EHR nudges to reduce medications in older adults. Several studies on AI use and calls for transparency in medical publishing. Policy proposals for device transparency and concerns about transplant access.