

The Life Scientific
BBC Radio 4
Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future
Episodes
Mentioned books

Oct 17, 2017 • 40min
Tim Birkhead on bird promiscuity
Professor Tim Birkhead talks to Jim Al Khalili about his 40 years of research on promiscuity in birds, his love of Skomer Island and its guillemots, and the extraordinary musical talent of the male bullfinch.Tim Birkhead is an evolutionary biologist and ornithologist at the University of Sheffield. The primary focus of his research has been reproduction in birds. He pioneered the study of promiscuity or extra-pair mating in birds, and one of its evolutionary consequences - sperm competition. In the early 1970s Tim questioned and then exploded the assumption that female birds were always sexually monogamous - a zoological dogma originating with Charles Darwin. Tim first explored this in the guillemot colony on Skomer Island in Wales: a population of seabirds which he has studied continuously for more than 40 years in the cause of both evolutionary insights and conservation. Tim talks with passion about an ongoing funding crisis that hit this research programme recently and how the public response to it has been the most inspiring event in his career.A side branch of Tim's research includes the jaw-dropping musical mimicry of the male bullfinch. The programme includes a recording of a captive bird whistling a German folk tune with super-human skill.ADVISORY! There is a longer version of the conversation in the podcast of this edition. In this edit, Tim talks about the truly weird false penis of the male red-billed buffalo weaver: an extreme evolutionary product of sperm competition in this species and what amounts to an avian tickling stick. Tim also addresses the controversial topic of sperm competition in humans and the myth of 'kamikaze sperm'. Producer: Andrew Luck-Baker.

Oct 10, 2017 • 28min
Steve Cowley on Nuclear Fusion
Steve Cowley has said that "fusion is arguably the perfect way to power the world". But he's had to add that "it is hard to make fusion work. Indeed, after more than 60 years of fusion research, no device has yet made more energy than it consumes". But Steve Cowley isn't giving up. He's spent over 30 years working towards making nuclear fusion a viable way of generating energy. Steve Cowley has done theoretical research on how to contain the incredibly hot material you need to get fusion going. As the Director of the Culham Centre for Fusion Energy he guided the British contribution to research. And he has led the UK's participation in ITER, an international experimental reactor being built in France that is planned to be the next step towards making nuclear fusion commercially viable. Jim al-Khalili discusses with Steve Cowley, now President of Corpus Christi College in Oxford, why nuclear fusion, which has such promise as a clean form of energy with no dangerous waste, has proved so hard to achieve.

Oct 3, 2017 • 28min
Lucie Green on the sun
Lucie Green studies the sun - that giant, turbulent ball of burning gas at the centre of our solar system. Her first ambition was to become an art therapist, but she soon switched from art to astrophysics, and before long had fixed her gaze on our local star. It may be 93 million miles away, but the sun's extensive and ever changing magnetic field determines the 'weather' throughout our solar system. Under a worst-case scenario, bubbles of super-hot plasma and streams of high energy particles - spat out when the surface of the sun erupts - can hurtle towards planet earth, damaging communication and navigation satellites and bringing down electrical power supplies.Thanks to the work that Lucie and others have done to raise awareness of these coronal mass ejections, solar belches as Lucie likes to call them are now a recognised threat to national security, alongside flooding, pandemic flu and terrorist attacks. Producer: Anna Buckley.

Sep 26, 2017 • 39min
Tracey Rogers on leopard seals and Antarctica
Marine ecologist Tracey Rogers talks to Jim Al Khalili about her research on one of Antarctica's top predators. This is the leopard seal - a ten foot long killer which glides among the ice floes in search of prey ranging from other seals to penguins to tiny krill. Tracey's research has encompassed the animal's prolific and eerie underwater singing to radical changes in its diet that appear to be linked to climate change.Now a senior researcher at the University of New South Wales in Australia, Tracey first encountered the species as a less than successful seal trainer at a zoo in Sydney. There she met a giant female leopard seal named Astrid. Astrid's singing one Christmas day in the early 1990s set Tracey on the path to become the world's authority on this Antarctic species.Tracey tells Jim how her first expedition to study leopard seals was met with almost universal scepticism until she dropped an underwater microphone into the water. In the following 25 years, she has worked to decode the meanings and qualities of the leopard seal song and explored the changes being forced upon the species by climate change. Tracey describes what made her return to Antarctica again and again and tells the story of how she almost met her end in the perilous shifting world of the pack ice. And then there's the time a leopard seal mistook her for a penguin. There is a longer version of this interview in the podcast of this episode - more on the seal vocalisations and how Tracey saved the life on a young colleague who fell into the freezing sea. Producer: Andrew Luck-Baker.

Sep 19, 2017 • 28min
Jennifer Doudna
Jennifer Doudna's research has transformed biology. And this is not an understatement. Her work has given us the tools to edit genes more precisely than ever before. Her scientific career began with work to understand the actions of RNA, part of the machinery of every cell. But, after a meeting in 2005 with a colleague at the University of California, Berkeley, where Jennifer is currently a professor of chemistry and of molecular and cell biology, she changed her direction of research. Through collaborations all over the world she's since developed the gene editing system called CRISPR/cas9. She's been awarded multiple prizes for her work. The CRISPR/cas9 system has created opportunities that could be used for both for good and for ill. Unlike many scientists who leave the ethical implications of their research to others, Jennifer Doudna has decided to engage with her critics. She talks to Jim al-Khalili about her decision to do this.

May 30, 2017 • 28min
Tamsin Mather on what volcanic plumes reveal about our planet
To volcanologist Tamsin Mather, volcanoes are more than a natural hazard. They are 'nature's factories', belching out a rich chemical cocktail of gases. It's these gases or 'plumes' that fascinate her the most. She likes nothing more than crouching on a crater's edge collecting a smouldering mix of ash and gases, a clue to what's brewing deep inside.As Professor of Earth Sciences at Oxford University, her work is helping to not only predict when a volcano may erupt, but to understand how volcanoes shape our planet both now and over geological time.Producer: Beth Eastwood.

May 23, 2017 • 28min
Tim O'Brien on transient stars and science and music festivals
Tim O'Brien has earned the nickname 'the awesome astrophysicist dude from Jodrell Bank' He is Professor of Astrophysics at Manchester University, and the associate director of Jodrell Bank Observatory, best known for the giant, iconic radio dish of the world-famous Lovell telescope which sits majestically on the Cheshire plain, where he carries out research on the behaviour of transient binary stars called novae. For twenty-five years Tim O'Brien has been telling the public about astronomy, and recently he's also become an organiser of concerts. Building on some very successful one-day events, the first Blue Dot Festival was held at Jodrell Bank in July 2016 and the second will be this summer. Tim talks to Jim al-Khalil about how he pops up on stage between acts to tell the audience about science - and doesn't get bottled off!

May 16, 2017 • 28min
Ottoline Leyser on how plants decide what to do
To the untrained eye, a plant's existence may seem rather uneventful. It spends its days rooted to the spot, seemingly at the mercy of its environment. Not so, plant biologist Ottoline Leyser explains to Jim Al-Khalili. Plants are intelligent creatures that possess a unique ability to adapt in ways we animals can only dream of. They can alter their entire body plan of roots and shoots, when required, in response to their surroundings. Now Director of the Sainsbury Laboratory & Professor of Plant Development at Cambridge University, Ottoline has spent her career unearthing the mysterious mechanisms that underpin this process. She's pieced together the finely-tuned network of hormonal signals which regulate how the roots and shoots of a plant develop.These new insights into what plants get up to are so remarkable that Ottoline is determined to change the way we think about them.Producer: Beth Eastwood.

May 9, 2017 • 28min
Fay Dowker on a new theory of space-time
For a long time Fay Dowker was mathematically precocious, but emotionally uncertain. These days, despite working in an area with few academic allies, she is more confident than ever. Her approach to a Theory of Everything, known as causal set theory, acknowledges the quantum nature of the universe and takes the arrow of time more seriously than Einstein. Bye bye time travel. Fay started her Life Scientific working on the assumption that the texture of the universe was continuous and smooth, with Stephen Hawking as her supervisor. But mid-career, she changed her mind. She now thinks in terms of 'atoms' of space-time. Down at the tiniest scale imaginable, the universe is granular, made of discrete entities that represent a point in space and a moment in time. Most theoretical physicists were shocked to discover in 1998 that the expansion rate of the universe was accelerating. Not the causal set theorists. Unlike everyone else, they were expecting this result. What's more, if causual set theory is right, there will be no need to explain dark energy, an idea which seems 'just wacky and a little bit malicious', to Fay. Producer: Anna Buckley.

May 2, 2017 • 28min
Ann Clarke on The Frozen Ark
Tiny tree dwelling snails, partula, were so abundant across French Polynesia that garlands of partula shells would be presented to visitors to the islands. But when immunologist Dr Ann Clarke joined her husband, the late evolutionary biologist Professor Bryan Clarke, on expeditions to research the unique way this species had developed, a study in speciation turned, before their eyes, into a study of extinction.
Ann witnessed first-hand the terrifying speed that biological controls, another mollusc introduced to kill a different, larger predatory snail, instead turned on Partula, and within a few short years, drove them to extinction in the wild.
The subsequent scramble to save the species resulted in the launch of a global effort called The Frozen Ark to save the genetic resources of all animals which, like partula, face obliteration.
The Frozen Ark was founded by Ann, her husband and the late Professor Ann MacLaren and with consortium members around the world, tissue and genetic material from threatened fauna is preserved as an ultimate animal conservation back-up. More than 48,000 samples have been collected by Frozen Ark members in zoos and natural history museums around the world from more than 5,500 different species. Frozen samples inform multiple captive breeding programmes, including at London Zoo, where descendants of partula rescued from extinction, are being bred ready for re-introduction back to their home in French Polynesia.
And all this wasn't Ann's main career!
As well as admitting to Jim that she was read bedtime stories as a child by the great JR Tolkien and that in her first ever job as a lab technician she helped Nobel Prize winner Sir John Gurdon with his nuclear transfer experiments, Ann also had a long and successful career as an immunologist and embryologist, fuelled by a life long interest in embryonic tolerance and immunity.


