Dhru Purohit Show

Dr. Jason Fung, nephrologist and bestselling author known for work on fasting and obesity. He argues hunger and hormones—not willpower—drive weight gain. Short, punchy sections explore three types of hunger, a body “fat thermostat,” how ultra-processed foods hijack hormones, GLP-1 drugs’ role, and three rules to reset hunger naturally.

Dr. Majid Fotuhi, a neurologist from Johns Hopkins and Harvard focused on memory and successful aging. He explains why brain decline is on a spectrum and often preventable. Short, practical strategies cover exercise, sleep, nutrition, mindset, brain training, and the surprising link between hearing loss and memory. Hear stories of measurable recovery and a five-pillar approach to strengthen the brain at any age.

Dr. Satchin Panda, circadian biology researcher and Salk Institute professor known for time-restricted eating and melanopsin discovery. He explores how light and sleep timing shape brain repair and dementia risk. He explains why meal and medication timing matter, how exercise aids detox and cancer resilience, and offers simple circadian habits to try.

Michael Easter, New York Times bestselling author who explores practical, science-backed health and behavior ideas. He explains why humans evolved to carry weight and how adding load to walks boosts calorie burn, bone density, and strength. Learn simple ways to start, gear tips, progression advice, and how weighted walking builds resilience, mental clarity, and social connection.

Dr. Mindy Pelz, a New York Times bestselling author and women's health educator focused on hormones and lifestyle medicine. She reframes menopause as a neurological and cultural transformation. Topics include brain pruning and leadership, neurochemical shifts that reshape priorities and relationships, metabolic and fasting strategies for midlife, and how partners can support this reinvention.

Dr. Nicole McNichols, a University of Washington human sexuality professor and author, explains why sexual pleasure matters for health and relationships. Short takes cover links to longevity, immunity, sleep, and cognitive health. She outlines a hierarchy of sexual needs, practical fixes for mismatched desire, and easy ways to revive connection through novelty, planning, and better communication.

Dr. Diana Hill, psychologist, ACT trainer, and author of Wise Effort, teaches compassion-driven tools to build psychological flexibility. She explores why pushing harder often backfires. Short, sharp topics include hidden mental traps that drain energy, wise effort versus forcing change, misaligned goals that exhaust you, and how aligning strengths with values restores vitality.

Dr. Gabrielle Lyon, a physician and expert in muscle-centric medicine, challenges the common perception of aging. She emphasizes that muscle health is central to longevity and resilience, urging a cultural shift towards strength training. Lyon introduces concepts like neutrality in mindset, explaining how it helps avoid emotional highs and lows. Drawing from inspiring stories of Navy SEALs, she shares tools for personal growth and emotional regulation. Ultimately, she highlights the importance of a deep 'why' to sustain purpose and action in life.

In this enlightening conversation, Jonathan Jarecki—a pre-med student focused on Biology and Neuroscience—reveals the profound impacts of sunlight on health and longevity. He shares compelling studies linking sun exposure to lower mortality rates and improved metabolic health. Discover how infrared light boosts mitochondrial function and how strategic sunlight habits can enhance well-being. Jonathan also introduces a 2026 Light Challenge, encouraging listeners to embrace natural light and mitigate artificial light for better health outcomes.

Dr. Ronesh Sinha, an internal medicine physician and author focusing on metabolic health, explores the emotional roots of chronic illnesses. He shares fascinating insights about 'surprise diseases,' revealing how emotional suppression can lead to chronic inflammation. Through case studies, like Sheila's early heart plaque, Ronesh highlights the impact of life events on health. He discusses the importance of emotional awareness, open family conversations, and offers practical strategies to improve emotional health and reduce disease risk.