

ICU Ed and Todd-Cast
Eddie and Todd
Two critical care guys walk into a recording studio and breakdown intensive care trials both old and new! We'll also do deep dives on specific topics important to practicing intensive care medicine and have special guests talking about their area of expertise! This podcast is made for educational purposes. The content provided in this podcast, and in any linked materials, is not intended and should not be construed as medical advice and should not be used to diagnose or treat any medical condition. We try to stay away from opinions but all opinions represent our own and not of any entity we work for. Please keep this in mind as you enjoy the podcast!
Episodes
Mentioned books

Mar 24, 2026 • 47min
New/New: PE and CPR Guidelines
They walk through brand new pulmonary embolism risk categories and how they change triage and treatment choices. They highlight timing and options for anticoagulation, advanced clot therapies, and follow-up for chronic thromboembolic disease. They also cover 2025 CPR and resuscitation guideline changes including BLS/ACLS updates, mechanical and extracorporeal CPR considerations, pregnancy resuscitation, and training innovations.

Mar 10, 2026 • 47min
Old/New: ALBIOS and ARISS
They dive into recent trials comparing albumin therapy strategies for septic shock and the history of prior landmark studies. They debate biological reasons to use albumin, trial design choices like dosing and targets, and how COVID and enrollment issues affected results. They discuss practical bedside decisions, cost and logistics, and whether current data justify changing practice.

Feb 24, 2026 • 48min
New: PreVent2
A lively dive into endotracheal tube designs, comparing subglottic suction and polyurethane cuffs with standard tubes. They unpack trial methods, consent ethics, and practical problems like suction blockage and tube size. Long-term quality-of-life as a primary outcome and complex VAP surveillance definitions spark debate. They weigh mixed signals from clinical outcomes, laryngeal injury risks, and real-world practice implications.

Feb 10, 2026 • 58min
New: LIBERATE-D with Eddie Siew
Send us a Text Message (please include your email so we can respond!)Episode 85! In this episode we go over LIBERATE-D or "A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury" by Liu et al in JAMA 2026. We have the second author, Eddie Siew, on with us to discuss!LIBERATE-D (pubmed): https://pubmed.ncbi.nlm.nih.gov/41201895/LIBERATE-D (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2841171If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jan 27, 2026 • 36min
CCR Down Under: ACTiVE and CLIP2
Send us a Text Message (please include your email so we can respond!)Episode 84! In this episode we finish up our discussion of the articles presented with the CCR Down Under Conference with ACTiVE (close loop ventilation) and CLIP2 (cryopreserved platelets for surgical bleeding). Both are neutral trials at best, so we took them both pretty short.ACTiVE: https://pubmed.ncbi.nlm.nih.gov/41361939/ACTiVE (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842610CLIP2: https://pubmed.ncbi.nlm.nih.gov/41360717/CLIP2 (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842479If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Jan 13, 2026 • 47min
CCR Down Under: ImmunoSep
Send us a Text Message (please include your email so we can respond!)Episode 83! Only one article this episode since Todd is feeling a little under the weather, but still a good discussion!ImmunoSep (JAMA): https://jamanetwork.com/journals/jama/article-abstract/2842634ImmunoSep (pubmed): https://pubmed.ncbi.nlm.nih.gov/41359996/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 30, 2025 • 46min
2025 Year in Review
Send us a Text Message (please include your email so we can respond!)Back by popular demand, year in review! Or probably better titled "Our Favorite Articles of the Year" but I kept the title from last year. A smattering of papers and topics in this one ranging from avalanche survival, to intubation, to cardiac resuscitation and more. Happy New Year everyone! We will see you in 2026, thanks for listening and spending sometime with us.If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 16, 2025 • 1h 3min
New: MODS with Yonathan Freund
Send us a Text Message (please include your email so we can respond!)Episode 81! In this episode we talk to Yonathan Fruend the senior author on the MODS study looking at a single questions approach to ruling out pulmonary embolism in the emergency department. This is not our typical patient population but this is a good episode, don't miss this one!MODS: https://pubmed.ncbi.nlm.nih.gov/41135553/If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 10, 2025 • 1h 7min
CCR Down Under: RSI with Jon Casey
Send us a Text Message (please include your email so we can respond!)We start our Critical Care Reviews Down Under coverage with RSI talking with the first author of the "Ketamine versus Etomidate for Adults Receiving Emergency Endotrachael Intubation", Jonathan Casey! We will pick up the rest of our CCR Down Under Coverage after the holiday break!If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!

Dec 2, 2025 • 58min
New/New: EVERDAC and ANDROMEDA SHOCK 2
Send us a Text Message (please include your email so we can respond!)Episode 79! We talk all about perfusion with arterial lines in EVERDAC and personalized resuscitation with ANDROMEDA SHOCK 2! EVERDAC: https://pubmed.ncbi.nlm.nih.gov/41159885/EVERDAC (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2502136ANDROMEDA SHOCK 2: https://pubmed.ncbi.nlm.nih.gov/41159835/ANDROMEDA SHOCK 2(JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840823If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!


