Modern Healthspan

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey will talk about the hallmarks of aging that he defined and more specifically about the stiffening of the extra cellular matrix a hallmark that was in his original list but not the 2013 paper.   Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process.   The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime  https://amzn.to/37lBX7A   SENS Foundation   https://www.sens.org/ 2013 paper on the 9 hallmarks of aging  https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging  https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging

In this show, Dr. Kennedy discusses the work he is doing in Singapore where he is taking a very practical approach to try and show, without long and expensive trials, what interventions work for extending healthspan in humans. He covers his work with the government and the trials that he will be running.   Dr. Brain Kennedy is a Professor in the Departments of Biochemistry and Physiology at National University of Singapore and Director of the Centre for Healthy Ageing at the National University Health System. From 2010 to 2016, he was the President and CEO of the Buck Institute for Research on Aging. He remains a Professor at the Institute. Dr. Kennedy is internationally recognised for his research into the biology of aging and for his work to translate research discoveries into new ways of delaying, detecting, and preventing human aging and its associated diseases.  At National Univeristy of Singapore , Dr. Kennedy’s broader goals are to develop new interventions to target human aging and to validate their efficacy in humans. And ultimately, to create strategies to promote their widespread use.   TED TALK LINKS OF DR. KENNEDY  https://www.youtube.com/watch?v=E91fk6D0nwM   Medical Revolution: Targeting aging directly | Brian Kennedy | TEDxOnBoard https://www.youtube.com/watch?v=iGSkpIRs6pc Live Healthy Longer: Healthspan vs. Lifespan: Brian Kennedy at TEDxMaui 2013  

Dr. Snyder is the Stanford W. Ascherman Professor and Chair, Department of Genetics and Director, Center for Genomics and Personalized Medicine at Stanford University. He is a leader in the field of functional genomics and proteomics. Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated, and a high diversity of transcription factor binding occurs both between and within species. He has also pioneered the use of different state-of-the-art “omics” technologies as well as wearable devices for managing human health. In this video, Dr. Snyder will discuss with us the benefits and methods of checking your health in depth when you are well so that you can quickly detect and react to issues as they arise, leading to better health outcomes. Some resources for more information on Dr. Snyder: Dr. Synder Book: Genomics and Personalized Medicine: What Everyone Needs to Know https://amzn.to/3309oLD Dr. Snyder’s Lab at Standford University http://med.stanford.edu/snyderlab.html

Professor Kaeberlein talks about the work that his lab is doing and how  he views aging in this video. He also touches on how the message is  being more widely received,    Dr. Matt Kaeberlein is a Professor of Pathology, Adjunct Professor of  Genome Sciences, and Adjunct Professor of Oral Health Sciences at the  University of Washington. His research interests are focused on basic  mechanisms of aging in order to facilitate translational interventions  that promote healthspan and improve quality of life. He is currently  leading The Dog Aging project, a large multi-year trial to study the  aging of companion dogs in a normal environment.   He has published nearly 200 papers in top scientific journals and has  been recognized by several prestigious awards, including a Breakthroughs  in Gerontology Award, and most recent GSA’s 2020 Robert W. Kleemeier  Award   Professor Kaeberlein at University of Washington https://depts.washington.edu/mbwc/about/profile/matt-kaeberlein  Dog Aging Project. https://dogagingproject.zendesk.com/hc/en-us

In this episode Professor Kennedy covers lifestyle topics such as intermittent fasting and diet as well as explaining how mTOR may behave as we age. And I was happy to hear that alcohol is not all bad Dr. Brain Kennedy is a Professor in the Departments of Biochemistry and Physiology at National University of Singapore and Director of the Centre for Healthy Ageing at the National University Health System. From 2010 to 2016, he was the President and CEO of the Buck Institute for Research on Aging. He remains a Professor at the Institute. Dr. Kennedy is internationally recognised for his research into the biology of aging and for his work to translate research discoveries into new ways of delaying, detecting, and preventing human aging and its associated diseases.  At National Univeristy of Singapore , Dr. Kennedy’s broader goals are to develop new interventions to target human aging and to validate their efficacy in humans. And ultimately, to create strategies to promote their widespread use. TED TALK LINKS OF DR. KENNEDY https://www.youtube.com/watch?v=E91fk6D0nwM   Medical Revolution: Targeting aging directly | Brian Kennedy | TEDxOnBoard https://www.youtube.com/watch?v=iGSkpIRs6pc Live Healthy Longer: Healthspan vs. Lifespan: Brian Kennedy at TEDxMaui 2013

In this video Professor Kennedy covers lifestyle topics such as intermittent fasting and diet as well as explaining how mTOR may behave as we age. And I was happy to hear that alcohol is not all bad Dr. Brain Kennedy is a Professor in the Departments of Biochemistry and Physiology at National University of Singapore and Director of the Centre for Healthy Ageing at the National University Health System. From 2010 to 2016, he was the President and CEO of the Buck Institute for Research on Aging. He remains a Professor at the Institute. Dr. Kennedy is internationally recognised for his research into the biology of aging and for his work to translate research discoveries into new ways of delaying, detecting, and preventing human aging and its associated diseases.  At National Univeristy of Singapore , Dr. Kennedy’s broader goals are to develop new interventions to target human aging and to validate their efficacy in humans. And ultimately, to create strategies to promote their widespread use. TED TALK LINKS OF DR. KENNEDY https://www.youtube.com/watch?v=E91fk6D0nwM   Medical Revolution: Targeting aging directly | Brian Kennedy | TEDxOnBoard https://www.youtube.com/watch?v=iGSkpIRs6pc Live Healthy Longer: Healthspan vs. Lifespan: Brian Kennedy at TEDxMaui 2013

In this video Professor Kennedy elaborates on the drugs that he is using in his lab and in his trials, including alpha-ketoglutarate and spermidine. He also gives his views on NAD boosters and rapamycin. Dr. Brain Kennedy is a Professor in the Departments of Biochemistry and Physiology at National University of Singapore and Director of the Centre for Healthy Ageing at the National University Health System. From 2010 to 2016, he was the President and CEO of the Buck Institute for Research on Aging. He remains a Professor at the Institute. Dr. Kennedy is internationally recognised for his research into the biology of aging and for his work to translate research discoveries into new ways of delaying, detecting, and preventing human aging and its associated diseases.  At National Univeristy of Singapore , Dr. Kennedy’s broader goals are to develop new interventions to target human aging and to validate their efficacy in humans. And ultimately, to create strategies to promote their widespread use. TED TALK LINKS OF DR. KENNEDY https://www.youtube.com/watch?v=E91fk6D0nwM   Medical Revolution: Targeting aging directly | Brian Kennedy | TEDxOnBoard https://www.youtube.com/watch?v=iGSkpIRs6pc Live Healthy Longer: Healthspan vs. Lifespan: Brian Kennedy at TEDxMaui 2013

Age Later: Health Span, Life Span, and the New Science of Longevity In Age Later Dr. Barzilai’s New Book - https://amzn.to/30MOsGT Aging and Centenarian Studies : This is the part 3 of our interview series with Dr. Nir Brazilai from Albert Einstein College of Medicine. Dr. Barzilai is the founding director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging.   Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others. In addition to his “longevity gene” research, Dr. Barzilai studies key mechanisms involved in the biology of aging, including how nutrients and genetics influence lifespan. He is also investigating the physical and mental declines associated with aging and how they affect longevity.   He is the author of over 270 peer-reviewed papers and a recipient of numerous prestigious awards,including the recipient of the 2010 Irving S. Wright Award of Distinction in Aging Research and is the 2018 recipient of the IPSEN Longevity award. Dr. Barzilai’s New Book - Age Later: Health Span, Life Span, and the New Science of Longevity In Age Later, the No.1 Best Sellers in Physiology section in Amazon, reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. In this video Dr. Barzilai draws on his long experience working in the aging field to talk about some of the ways that we can improve our healthspan. His data provides some, perhaps, surprising advice on the ideal BMI and exercise with metformin. Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.  Products or services mentioned in this video are not a recommendation. Disclosure: Some of the links provided are affiliate links.  Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel!

Age Later: Health Span, Life Span, and the New Science of Longevity In Age Later Dr. Barzilai’s New Book - https://amzn.to/30MOsGT Aging and Centenarian Studies : This is the part 1 of our interview series with Dr. Nir Brazilai from Albert Einstein College of Medicine.    Dr. Barzilai is the founding director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging.   Dr. Barzilai discovered the first longevity gene in humans and has since discovered several others. In addition to his “longevity gene” research, Dr. Barzilai studies key mechanisms involved in the biology of aging, including how nutrients and genetics influence lifespan. He is also investigating the physical and mental declines associated with aging and how they affect longevity.   He is the author of over 270 peer-reviewed papers and a recipient of numerous prestigious awards,including the recipient of the 2010 Irving S. Wright Award of Distinction in Aging Research and is the 2018 recipient of the IPSEN Longevity award.    Dr. Barzilai’s New Book - Age Later: Health Span, Life Span, and the New Science of Longevity In Age Later, the No.1 Best Sellers in Physiology section in Amazon, reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process.  In this interview Dr. Barzilai discusses his study of centenarians, what he learnt from that and how it can be applied. By studying centenarians and the mechanisms that keep them healthy he hopes to short cut years research and animal trials.   Health claims Disclosure: Information provided on this video is not a substitute for direct, individual medical treatment or advice. It is the responsibility of you and your healthcare providers to make all decisions regarding your health.  Products or services mentioned in this video are not a recommendation.   Disclosure: Some of the links provided are affiliate links.  Although we may receive a small commission from the affiliate, the cost of the product for you will always be the same, or often discounted. Thank you for supporting our channel! 

Our YouTube Channel is here Please visit us for more longevity and extended healthspan content. In this podcast Dr. de Grey talks about his view on the latest rejuvenation technology. Dr. de Grey is a biomedical gerontologist and is the Chief Science Officer and co-founder of the SENS Research Foundation, an organization that is dedicated to combating the aging process. The book by Dr. de Grey Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime https://amzn.to/37lBX7A SENS Foundation https://www.sens.org/ 2013 paper on the 9 hallmarks of aging https://www.sciencedirect.com/science/article/pii/S0092867413006454 Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging https://www.researchgate.net/publication/342138218_Stochastic_non-enzymatic_modification_of_long-lived_macromolecules_-_A_missing_hallmark_of_aging