Longevity Optimization with Kayla Barnes-Lentz

Dr. Eboni Cornish, a board-certified physician and functional medicine director focused on neuroinflammation and chronic infections. She discusses hidden drivers of brain problems like mold, Lyme, toxins, and oral/gut imbalances. Imaging and biomarkers that reveal early brain stress come up. Practical foundations for brain longevity such as sleep, exercise, omega-3s, vitamin D, hormones, and detox are highlighted.

Jessie Inchauspé, biochemistry-trained author known as the Glucose Goddess, explains why blood sugar patterns matter for mood, energy, cravings, skin aging, and pregnancy. She shares surprising CGM discoveries, common glucose mistakes, simple stabilizing hacks like food order and walking, and how maternal spikes can shape a child’s long-term metabolic risk.

Dr. Deanna Minich, PhD, a functional medicine practitioner and nutrition scientist. She explains circadian timing for meals, macro ranges tailored to pre-, peri-, and postmenopause, and why flexible ranges beat rigid targets. They cover carb roles for ovarian health, protein strategies for aging, omega-3 testing, fiber goals, and practical cooking and oil choices to protect metabolic and bone health.

Dr. Susanna Søberg, PhD, scientist and educator focused on metabolism, cold and heat exposure, and longevity. She explains cold as a short hormetic stressor, why brown fat matters for metabolic health, and how timing cold around the menstrual cycle can change effects. Short, strategic cold exposures and combining cold with heat or exercise get emphasis.

Dr. Stephanie Riley Hahn, pelvic floor physical therapist and founder of Longevity PT and Pilates, blends decades of clinical experience and authorship. She breaks down pelvic floor tightness versus weakness. She explains breathing and pressure management, downtraining versus strengthening, prolapse supports, bladder retraining, and practical tools and assessments for real-world care.

Dr. Aimie Apigian, double-board-certified physician and trauma expert who created the Biology of Trauma framework, explains how trauma is a measurable physiological response. She outlines how adrenaline and cortisol shape reactions, how trauma is stored as body patterns, and practical somatic tools to create safety, titrate healing, and expand nervous system capacity.

She reveals being the first person to take a new ovarian age test and explains how the machine learning algorithm uses hormones, body composition, and history. She outlines plans to test interventions like hyperbaric oxygen therapy and isolation protocols. She reviews five proposed drivers of ovarian aging, from mitochondrial dysfunction to fibrosis, and practical steps to support ovarian health.

Cynthia Thurlow, board-certified nurse practitioner and functional medicine expert focused on women’s metabolic health. She explores how perimenopause is a metabolic shift affecting insulin sensitivity, gut health, stress resilience and timing of symptoms. Short takes on fasting, exercise recovery, gut dysbiosis, hormone testing variability, and practical lifestyle tweaks for midlife metabolism.

Dr. Chris Masterjohn, PhD, nutrition scientist focused on micronutrients, metabolism, and mitochondrial health. He explains why mitochondrial function limits energy and progress. He highlights micronutrient bottlenecks, creatine as cellular energy wiring, and why sunlight and vitamin D pills are not equivalent. He outlines practical strategies like testing, sleep, varied exercise, and targeted supplements.

Dr. Jessica Shepherd, board-certified OB/GYN and menopause expert, focuses on evidence-based hormone care and longevity. She unpacks the FDA removal of the HRT black box warning and clarifies the WHI study confusion. Timing matters: start HRT conversations in perimenopause. She highlights bone health, essential labs like ApoB and HbA1c, and the roles of inflammation, creatine, and personalized hormone strategies.