Live Long and Master Aging

Living life to the full, at any age, has been a challenge recently.  To put it mildly.  But if Covid has taught us anything, it is that some of life's simplest pleasures are what make life itself worth living. Therein lies a metaphor for healthy aging.  Physical fitness, social contact and an active mind go a long way towards helping us live longer and better.  They are also central to the ideals of Aging is Cool, a Texas-based company that helps people over fifty stay active and engaged as they age. In this LLAMA episode, Aging is Cool co-founder, Amy Temperley, explains why she rails against a modern-day culture rife with ageism and how she hopes to redefine what it means to grow old. "Old is a feeling and I don't know that you're old until you decide that you're old," she says.  In conversation with Peter Bowes, Amy also reveals how life with Covid has opened her eyes to the everyday activities that bring pleasure and purpose to life. Recorded: March 22, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Targeting healthy, active aging and coming up with the idea for Aging is CoolRealizing that aging can be positive, celebrating a robust zest for life and it is okay to get older.  Is there a benchmark for becoming oldAnti-aging versus finding a sense of purpose in life. Building a company focussed on mind and body training for older adultsA Mighty Good Time -  a one-stop-shop and mostly virtual resource for adults aged 50+Over fifty - is there a mindset change? Reducing social isolation through involvement in a communityThe value of friendship and forging new relationshipsSocial interaction post Covid and find new joy-inducing pastimes. How making stuff can be fun. Advocacy for the benefits of a healthy, aging population. Breaking out of Covid, socializing more and multi-generational friendships. Morning rituals that include caring for dogs. Finding those things that make life worth living - "embracing the things you love rather than lamenting what you've lost."This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Cracking the code behind aging has long since fascinated, frustrated and captivated scientists.  In our quest to live longer and better, a desire to fully understand the mechanisms that explain how and why we grow old, has been central to longevity research. In recent years some significant progress has been made. A clearer picture is emerging of the changes that occur, at a cellular level, that could dictate how our bodies respond to the passing years. In this episode of the LLAMA podcast, Prof. David Walker, a researcher at the University of California, Los Angeles, (UCLA) discusses his work with tiny worms and fruit flies, and explains the significance of myriad age-related issues, such as dysfunctional mitochondria, leaky intestines and inflammation. Recorded: March 2, 2021 | Read a transcript and show notes at the LLAMA podcast website.Disclosure: Prof. Walker is a member of the scientific board of JUVICELL, a sponsor of this LLAMA podcast episode. Topics covered in this interview include:Dr. Walker's academic journey from Belfast to Manchester and Los Angeles. Inspiration through  Jonathan Weiner's Time, Love Memory - a biography of Seymour Benzer, the biologist renowned for his study of genetics through experiments with fruit fly genes.  Working with nematode worms and fruit flies.  Aging - a great scientific mystery.  How our understanding of what is driving aging, at a cellular level, has evolved. Developing novel ways, using genes, to prevent age- related health decline.  Changing awareness of aging as we grow older.Accumulation of dysfunctional mitochondria and how it appears to be an important cellular hallmark of aging. The importance of autophagy for maintaining cellular health.Why do we age at different rates?  The pathophysiology of aging: How do age-related changes that affect organ function, relate to the health and viability of the aging organism?    Leaky intestines in fruit flies and humans . Inflammation and the link to age-onset diseasesGut bacteria and relevance to various diseases and health interventions. Diet and variability of our gut microbiome.High/low  protein diets and the aging gut, based on fruit fly studies.  Does eating less protein enhance longevity? Making better informed decisions about diet and dietary supplementation. Practicing "  common sense" lifestyle goals. Exercise and everyday diet    to counter the effects of aging. Memory loss  as we age and a better understanding of the mechanisms involved based on studies with fruit flies. Lifestyles focussed on living life to the full.This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Baby boomers make up a significant portion of the world's population.  In the US and the UK the generation born between 1946 and 1964 represents about a fifth of all people and is a hugely influential group.  So what's it like to be a boomer in 2021?  Many are still working, physically active and important contributors to the economy.  Others are retired and enjoying the fruits of their careers, while some are facing up to the challenges of life as a septuagenarian.  "My almost fervent, religious conviction is we can all do better," says Dave Frost, a decorated naval officer,  world-ranked oarsman and Master Fitness Trainer.  Dave was born in 1953. The San Diego-based author of KaBoomer: Thriving and Striving into Your Nineties is the founder of Well Past Forty, a company that promotes wellness and fitness for athletes of all ages and abilities. In this LLAMA podcast interview, with Peter Bowes, he discusses his gregarious approach to life, ambitious athletic goals and plan to "live large" into his tenth decade. Recorded: March 16, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:What is it like to be a baby boomer in 2021?Dave's definition of the "encore" years and what it means to live in the "best act yet" of our lives. Living through the bottom of the happiness curve.Figuring out the daily activities, including motion and purpose, that enhance life. The life-changing impact of 911. Embracing the Loma Linda, low stress, outdoor lifestyle, for longevity. The importance of breathing for everyday health and good sleep. The joy of distance running and how the runner's high can be achieved with alternatives forms of exercise, as we get older. The value of exercise, quiet time, mind-body alignment  and "living large" as we age into our nineties. "We know aging is unavoidable, but we don't have to get old."The Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Why do we rush to the refrigerator during commercial breaks, while watching television?  Are we really hungry or does TV fuel our addiction to foods that we know are bad for us? "Without your agreement at all, you're doing what we call the robot walk or the zombie walk to the kitchen to get something to eat," says Joan Ifland, Ph.D., author of the textbook, Processed Food Addiction. Dr. Ifland believes we are wired to snack, in response to stress, excitement and suspense, and that an addiction to sugar and processed food is making us sick. In this LLAMA podcast interview, with Peter Bowes, she discusses her mission to help people recover from an addiction to processed foods and why, she says, cleaning up our diets, especially ridding them of sugar, could add years to our lives.Recorded: February 18, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:In this interview we cover: Melding the worlds of business and nutrition researchExploring what Dr. Ifland says is the role of corporations "in the spread and maintenance of addiction to processed foods"What is processed food? The difference between processed plant and animal-based foods. Food cravings, marketing, stress and addiction. How do we take control of what we eat, to avoid unhealthy foods - or "bad" foods - and what Dr. Ifland describes as "artificial aging" "Somebody who is seventy years old can feel fifty or even forty or they might feel better than they've ever felt in their lives."Why is it so difficult to give up certain foodsWhat is "conformance drive" and how does it influence what we eat. Associating with others, online, to build an immersion experience with healthy peopleDr. Ifland's diet change, 25-years ago, that she says eliminated cravings and "brain fog"Why do we fall off the wagon and return to bad eating habits? How does the Addiction Reset Community work?The connection between watching the television and eating too much. The impact of Covid on "clean" eating and food addictions. The "purpose" of living a long healthy lifeThis episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

At the age of eighty-one, Jean Ketcham is looking forward to sky diving again, when the pandemic is over. The co-founder of Aging But Dangerous, an international women's movement promoting active, healthy aging, is on a mission to empower women over fifty to live their lives to the full.  When Jean retired, she and her friend, C. Suzanne Bates, realized that their social circles were shrinking and that their friends were becoming less adventurous. Convinced that life still had much to offer, the pair set up the group to encourage women to live dangerously, as they age. In this LLAMA podcast interview, with Peter Bowes, Minneapolis-based Jean discusses her zest for life, optimism and aspirations for the next two decades. Recorded: February 2, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Challenging the "trauma" experienced by women turning 50 What's wrong with the word 'aging?'Cataract surgery at 80 Setting up Aging But DangerousInspiration from Jane Fonda and Lily TomlinMartini Jump Skydives, fashion shows and colonoscopy prep parties for women over 50  Inner strength, positivity and surviving cancer Finding the silver lining in the face of negativity Embracing social media, hosting Facebook lives for a multi generational audienceJean's advice to her younger self about weight and self-esteem Having fun full-filling a mission to connect with and help women An octogenarian's bucket list and aspirations This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

If you're a fast walker, you're likely to live longer. The correlation between walking speed and lifespan has been widely studied and is a good indicator of our general physical condition and the number of years that we are able to enjoy optimum health. "It is a wonderful predictor," says, Dr. Cliff Bleustein, Global President and CEO of AposHealth, a home based exercise program aimed at helping patients with their mobility. In this episode we delve into the importance of a healthy gait, sometimes described as the sixth vital sign. Dr. Bleustein explains the link between the natural ability to take a brisk walk and maximally performing bodily systems, such as the heart, lungs and musculoskeletal. Recorded: January 26, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Dr. Cliff Bleustein's "eclectic" career, encompassing surgery, research, business and healthcare consulting. Making the shift from treating patients to the business of healthcare Treating osteoarthritis of the knee by changing the way people walk Earlier health management of chronic conditions to improve health outcomesRehabilitation based on physical therapy rather than surgery Purposely including short bursts of exercise during the day for optimum health and maintenance of muscle massThe cumulative impact of exerciseGait - the sixth vital sign and predictor of long life. Walking speed as an indicator of healthThe daily activities that cost nothing and promote physical health The impact of Covid-19 on general healthcare, and the switch to telemedicine Future problems caused by plummeting activity levels during the pandemic The physical and emotional health impact of taking fewer steps a day through working at homeWhy healthcare facilities should be considered safe for preventative interventions, even as Covid continues to be a threatTaking small steps every day to pursue health and longevity. There are only so many things we can control.  Don't worry! This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Nutritional supplementation is one of the most frequently raised topics in relation to longevity and healthy living.  But do we really need additional components in our diet, such as pterostilbene , sulforaphane and resveratrol?  Scientifically validated studies suggest some dietary supplements are beneficial to our health, but how do we decide which ones to take?  There are myriad considerations. To explore the subject, the LLAMA podcast is teaming up with JUVICELL, a nutraceutical product developed by US and German scientists. In this conversation with Peter Bowes, co-founder, Erin Sharoni, discusses the scientific, ethical and societal issues involved in developing a product that aims to extend healthspan. Recorded: February 15, 2021 | Read a transcript and show notes at the LLAMA podcast website.The study of epigenetics and what it means. Our internal and external environments and how they interact.   Erin's "obsession" with the human body and how it changes over time.  Does living like an elite athlete help us live longer?The basic protocols for good health, like sleep, diet and hydration that impact longevity The most basic lifestyle traits that help us thrive.Why there is no magic bullet to optimum health.  The insurance policy approach to dietary supplementation.      The power of fasting and the work of Dr. Valter Longo at the university of Southern California (USC).   The idea and mission behind JUVICELLWhy the mission is to help people optimize healthspan rather than lifespan.Explaining the ingredients that go together to form an all-in-one dietary supplement. Safety, supplementation and ethical responsibility to follow the science. Lessons from the Covid pandemic and the big changes needed at a societal level to enable healthier populations. Sleep, whole foods, meditation and other lifestyle components to promote every day health and longevity.  This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Cognitive decline is an all-too-familiar hallmark of age-related diseases, such as Alzheimer's and Parkinson's. While there is much research that focuses exclusively on functional changes in the brain, the so-called gut-brain axis  - a connection between the digestive system and the central nervous system - also appears to play a pivotal role. It raises the question: Could nutritional interventions, to nurture the health of the gut microbiome, also help prevent or reverse age-related dementia?  In 2018, Dr. Julie Andersen, a scientist at the Buck Institute for Research On Aging, in California, received a $3.8 million grant to explore the hypothesis.  In this LLAMA podcast episode, Dr. Andersen discusses the work of her laboratory, and the idea that a gut metabolite, urolithin A, could play an important role in the treatment of Alzheimer's disease. Recorded: February 9, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Working at the Buck Institute for Research On Aging - the only freestanding institute studying aging and age-related disease.A multi-disciplinary approach to aging research, embracing a range of diseases and mechanisms that drive-age related conditions. Evolving definitions of aging.Exploring autophagy, mitochondrial function, urolithin A and muscle health, in relation to Parkinson's and Alzheimer's disease. The science and logic behind restoring an older person's gut microbiome to that of a younger person. Building on "exciting" clinical trials, by Amazentis, looking at the efficacy, in older humans, of Urolithin A, to enhance muscle function.Exploring the relatively new area of study known as the gut-brain axis.Explaining the scientific process, grants and clinical trials.How preliminary preclinical trial data suggests urolithin fed to mice may prevent cognitive loss associated with Alzheimer's disease.  Turning 60 and aspirations for a long healthspan. This episode is brought to you in association with Amazentis, a Swiss life science company, that is pioneering cutting edge, clinically validated cellular nutrition, under its Timeline brand.Related episodes:David Katz: Robust health beyond the pandemicStuart Phillips: Boosting physical strength as we ageStephanie Blum: Embracing and marketing the science of wellbeingJohan Auwerx: Enjoying youthful vitality as we ageNavindra Seeram: The rejuvenating power of plantsPatrick Aebischer: A novel molecule to promote longevityAnurag Singh: Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

When the pandemic struck, instead of hunkering down, with her life on hold, Alison Weinlaeder moved into top gear with her brain-child, a new online business melding physical and mental workouts.  The speech-language pathologist, from Saint Paul, Minnesota, wanted to help people improve their cognitive abilities, at the same time as nurturing their cardiovascular fitness. Cardiomelon is a fitness program that puts the essential components of daily health at its core. In this LLAMA podcast interview with Peter Bowes, Alison explains the science behind her novel approach to fitness.  She also shares the challenges and rewards she enjoys through a startup focussed on helping people live longer and better.Recorded: January 22, 2021 | Read a transcript and show notes at the LLAMA podcast website.This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.comTopics covered in this interview include:Why we should work on keeping the brain healthy and strong as well as the bodyWorking, as a speech language pathologist, with people who've experienced tragic and traumatic eventsPushing the brain outside its comfort zoneThe challenged posed by virtual therapy for patients with severe brain injuriesLaunching Cardiomelon in the midst of a pandemicIsn't it just normal to forget things as we get older? Empowering people through brain-focussed exercise How gardening  and walking can help boost brain performance.Building a brain workout programme based on the concepts of rehabilitation - the principles of neuroplasticityWhy you've got to use it to improve itWhy just doing mental workouts, without always succeeding in a challenge, will improve brain health  Never too late or early to start.  Partnering with Hilarity for Charity with a mission to educate people in their 20s about poor health habits that could lead to Alzheimer's The evidence to support combining cognitive and physical exerciseLearning how to think smarter, through visualization and habits Being empowered to control brain healthThe lifestyle habits that will determine how our lives will be like, decades in the future.Future science-based  research into the outcomes from CardiomelonThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

After a diagnosis of lupus, in her 30s, Leslie Kenny was told she had a life expectancy of five years. The prognosis focussed the Berkeley and Harvard grad's mind like never before. Long before biohacking was a thing, Leslie set about changing her lifestyle, embracing safe, natural solutions, in a fight for her life. Now 56, she is aging well, healthy and a fully signed up biohacker. She is the founder of Oxford Healthspan, a UK-based company, working with leading scientists to identify safe compounds as nutritional supplements. In this LLAMA podcast conversation with Peter Bowes, Leslie discusses her own unique journey, as well as the science and life-enhancing potential of spermidine, a compound that has been shown to be vital to myriad bodily functions. Recorded: January 19, 2021 | Read a transcript and show notes at the LLAMA podcast website.This episode is brought to you by AgeUp, a new financial product that provides guaranteed supplemental income for people who worry about the financial impact of longevity. To find out more, visit Age-Up.comTopics covered in this interview include:Leslie's journey from Swiss banking to biohacking Facing up to Lupus and a five-year life expectancy One's own mortality and the limits of longevityPillars of preventative healthcare: sleep, movement , diet, friendship, familyWhy your health is your wealthDiscovering the polyamine compound spermidine and establishing Oxford Healthspan Where does the name spermidine come from and what is it? The evidence for the benefits of spermidine - epidemiological  studies and clinical trials Is spermidine supplementation safe? How do consumers make decisions about which supplements to take?  Living life with the promise of healthspan rather than lifespan Disease prevention versus disease care The lifestyle of a biohacker - sleep hygiene, good food, lowered stressThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.