Live Long and Master Aging

HealthSpan Media
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Jun 23, 2021 • 38min

Nora Khaldi: Plants, peptides and wallabies

The power of food - plants in particular - to help us optimize our health and potential longevity can not be underestimated. Indeed nature itself is arguably the most powerful tool we have to thwart disease and the ravages of the aging process.  Dr. Nora Khaldi is the founder of Nuritas, a Dublin based biotechnology company that's pursuing a theory that natural foods contain all the molecular tools people need to optimize their health and wellbeing.  Dr. Khaldi has an ambitious goal to make revolutionary discoveries, through the study of plants, that will allow people to live healthier for longer.  In this LLAMA podcast conversation with Peter Bowes she explains the remarkable potential of peptides discovered in the fava bean to supports muscle health in people. She also discusses the astonishing complexity and relevance of wallaby milk to the building blocks of the human body. Recorded: April 28, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Approaching life science with a diverse academic background, including pure mathematics.Bioinformatics, molecular evolution and comparative genomics. Looking at a human bodies as a system of interactionsWhy do wallabies and their milk matter? The importance of peptides - short strings of amino acids - and where they are found. Harnessing the power of peptides discovered in the fava bean plant  to supports muscle health.Exploring the full potential of food and plants through Nuritas and Elio™.Translating the positive finding of science to benefit consumer needs.  Supplementation, do I really need it? Starting conversations with health providers about precision supplementation. Food as the problem, but also the solution.  Creating healthier versions of food without compromising on taste.Devising a lifestyle to achieve a good healthspan.Living longer but also being sicker for longer. Is living to 120 a realistic goal?   The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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Jun 9, 2021 • 54min

Jon Pearlman: Unleashing the inner athlete

Finding the most effective workout and diet regime, with the goal of getting fit and lean, is, for many, the ultimate challenge.  Even elite athletes struggle as they strive to achieve their peak level of performance.  Jon Pearlman, a former #1 singles player for the Harvard tennis team, learned through personal experience that athletic prowess does not come easy.  The two time All-Ivy athlete and ATP-ranked touring professional, had performance setbacks as a young tennis player but he learned through his struggles and now advises others on the best way to build a healthy, lean body for life.  In this episode of the LLAMA podcast, the author of The Lean Body Manual and co-founder of the fitness app, Mission Lean, discusses his mission to help people transform their bodies and defy their age. In conversation with Peter Bowes, Jon discusses the pros and cons of a 'strength and conditioning' approach to fitness training; explains why he prefers to workout on an empty stomach; and why he believes there's an "inner athlete" just waiting to be discovered in all of us. This LLAMA podcast episode is co-produced in association with Mission Lean, the fitness app that offers more than 150 on-demand workouts, specifically designed and curated to get you lean.Recorded: April 27, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Jon's personal journey to peak physical fitness.Experimenting with different workout regimes. Overcoming fitness obstacles by focussing on lean fitness methods.Obsession and determination to achieve peak physical fitness and a performance  edge.Questioning the value of weightlifting and a 'strength and conditioning' approach to fitness training. The importance of muscle strength for older people.Achieving optimum fitness and finding the best workout to make it happen.Takeaway lessons from Jon's experience training with the world's top tennis playersThe Lean Body ManualDefining the fitness goal - physically and mentally - before setting out to achieve it.     Adapting to using an app as a fitness coach.Heart-rate zone training and a Mediterranean diet. Lifestyle hacks and how, what and when to eat.  The age-old debate about the most important meal of the day.  Figuring out an "ideal harmony" between working out and eating. Exercising with an app and developing the right mindset to achieve success. The impact of Covid on at-home workouts Personal longevity aspirations and latching on to the inner athlete.  Prolonging healthspan through a commitment to a structured fitness programThe Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you shouldFit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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Jun 2, 2021 • 38min

Jenny Etnier: A lifetime of exercise to boost the brain

Making exercise a daily routine, from childhood, could be the key to preventing or slowing down some of the diseases of old age. Multiple studies have demonstrated the efficacy of physical activity, in improving cognitive health, throughout the human lifespan. Jenny Etnier is a professor of sport and exercise psychology in the Department of Kinesiology at the University of North Carolina. Working with children and older adults she is an advocate for exercise to nurture the mind and stimulate a healthy brain.  In this LLAMA podcast episode, with Peter Bowes, Dr. Etnier explains the lifetime benefits of physical education in schools; the meaning of mental toughness; and the reason why we should all enjoy a few minutes of "pure joy" every day. Recorded: May 4, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Helping children have a more positive youth sport experienceTaking a lifetime approach to physical activity for all ages, for mental healthMaking exercise a lifetime habitThe value of physical education in schools. Jenny's exposure to exercise leading to a lifetime of sport and coaching. Parents' priorities and goals for their children and sports. Learning how to self reference for personal joy and improvement. Walking basketball - why not?The mental health benefits of physical activity, movement and exercise. How our lives have changed, for the better, during Covid, emphasizing exercise.Quantifying the cognitive benefits of physical activity.    Mental toughness and the notion that it also applies to how we live our daily lives - time management and stress.  Physical activity to delay   the onset of symptoms for people at risk from Alzheimer's.  Making a regular commitment  to sport with a partner. Setting aside a few minutes for pure joy every day. Future studies: the timing of a single session of exercise for better memory the next day.This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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May 26, 2021 • 36min

Morgan Levine: Using epigenetic clocks to determine biological age

We are all used to feeling younger than our years and occasionally older than our birth date would suggest.  In effect, we have two ages - chronological and biological. Chronological age simply states the number of years that we have been alive, whereas biological age is a measure of how well our bodies are performing, in relation to the rest of the population.  So how is it determined?  LLAMA host Peter Bowes delved into the science with Elysium Health, which has developed Index, a DNA test that tracks how fast we have been aging, based on our epigenome, which regulates the way genes work.  In this episode, Peter meets Dr. Morgan Levine, an assistant professor of pathology at Yale School of Medicine and an advisor to Elysium Health. They discuss the background to Index, its use of epigenetic clocks to put a number to our biological age, as well as the test's accuracy and implications for healthy living. Recorded: April 21, 2021 | Read a transcript and show notes at the LLAMA podcast website. Topics covered in this interview include:Defining biological age and chronological age. Age as a risk factor for death and diseaseHaving an older parent and developing an interest in aging A lack of consensus over what exactly is meant by aging.How much of aging can be defined as damage to the body, at a cellular level, as we grow older?How do we measure biological age?  Genes, genomes and the epigenome.Developing systems that determine biological age based on epigenetic clocks.Exploring the Index epigenetic, at-home saliva test, to determine biological age.    Privacy concerns related to sharing personal medical information.  Revealing Peter's biological versus chronological age. What does it mean? Interpreting the test results and taking action based on the findings.Does the test reveal information specific to potential medical conditions?How do doctors - primary care physicians - respond to the information gleaned from such tests? The paradigm shift from disease treatment to interventions that delay illness. Lifestyle interventions that promote a long, healthy life.  The reliability of biological age tests. Do repeat tests over a short space of time generate the same results? To what extent do results vary between young and older people? Lifespan and healthspan aspirations. Disclosure: For review purposes, Elysium Health provided Peter Bowes with an Index test kit, free of charge .This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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May 19, 2021 • 43min

Daniel Kennedy: Longevity secrets from around the world

Some of the world's healthiest people spend little or no time pondering their propensity to live a long life.  They just do it. Their lifestyles are a model for longevity. There is much we can learn from these vibrant populations, in countries such as Italy, India, Japan, and (even) parts of the United States.  In this episode of the LLAMA podcast with Peter Bowes, filmmaker Daniel Kennedy discusses his quest to better understand global food and ancient healing traditions. Daniel's documentary series, Healthy Long Life, is an exploratory journey around the globe and considers the discrepancy between lifespan and healthspan; he asks why, for many people, the final years of life are spent in sickness and pain and shares observations about spirituality, mealtime traditions and chronic diseases. Recorded: April 19, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Filming Healthy, Long Life over four years and Daniel's motivation behind the project Lifespan vs healthspan and what it means for our children and grandchildrenAre chronic diseases pre-determined?  Searching for answers. Deriving inspiration from people with cancer to help others avoid the diseaseMeeting physicians who use plants as medicine, including T. Colin Campbell, the author of the China Project Pinpointing the world's longevity hotspots and learning from ancient healing traditions Fighting illness or promoting health? Plant based diets and the risk of contracting cancerScience, spirituality, food and faith The long lives of Seventh Day Adventists from Loma Linda, CaliforniaThe idea that "genetics may load the gun but it's diet and lifestyle that pull the trigger."The relative benefits of a healthy dietary regime and a life full of physical activity. Is there a French paradox - wine, cheese, butter and good health? Portion size and caloric restriction.This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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May 12, 2021 • 32min

Sandra Kaufmann: Setting the bar high to stop aging

The science of aging is so infinitely fascinating that Dr. Sandra Kaufmann decided to immerse herself in the field, as a hobby. A pediatric anesthesiologist from Florida, Dr. Kaufmann, is also an athlete who manages to fit swimming, running and rock climbing around her busy hospital schedule.  Determined to enjoy physical activity for as long as possible, she decided to carry out an extensive review of the scientific literature, to better understand our bodies as we grow old.  She focussed on the mechanisms of aging at a cellular level and set out to sort fact from fiction when it comes to the substances or interventions that might help us age more slowly.  The result is, The Kaufmann Protocol: Why We Age and How to Stop It, a book in which she sets out seven key tenets to maintaining optimum health. In this LLAMA podcast conversation, with Peter Bowes, Dr Kaufmann  explains everything from the importance of mitochondrial health and the maintenance of metabolic pathways, to her live and let live attitude towards eating a donut a day. In this interview we cover:Setting the bar high to "overcome all aging"The most ornate out-of-control hobby anybody can haveA light-bulb moment having off a cliff. Is it selfish to focus on the science of 'stopping' aging?Becoming a human guinea pig to try to figure out why cells age. Nurturing the seven protocolsDebunking myths - or ideas behind grandma's remedies - about interventions to slow down the aging processJunk food, including a donut a day.  Really? Being an exercise junkieBiohacking: striving to improve what we are, but is the term realistic? Feeling like a teenager at 52This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic - and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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May 5, 2021 • 41min

Simone Gibertoni & Adrian Heini: A holistic approach to healthspan

Embracing science and a holistic approach to living a healthier life, has been a hallmark of the Swiss spa-clinic, Clinique La Prairie (CLP), for the past ninety years. Known for its signature treatment, cellular therapy, the medical center opened in 1931, under the guidance of  Dr Paul Niehans, an early expert in the field. Today, CLP melds cutting edge technology with a mission to help people optimize their healthspan, though advanced clinical and wellness programs. The LLAMA podcast is teaming up with CLP to discuss the big issues surrounding human longevity. In this episode, Peter Bowes is joined by C.E.O. Simone Gibertoni and Medical Director, Dr. Adrian Heini.  In a wide-ranging conversation they cover the clinic's history, scientific developments, including Epigenetic screening, and the future of wellbeing as a priority in the post-Covid world. Recorded: April 20, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Clinique La Prairie's 90-year legacyThe history of a medical spa that melds science and luxury relaxation The scientific gatekeepers monitoring the science behind health and wellness programs Using natural tools to curate a holistic approach to living better and longerDevelopments in genetics and epigenetic tests to reveal predispositions to certain conditionsTailored  programs to focus on conditions such as oxidative stress and inflammationPlants, herbs and fatty acid profilesThe lifestyle trails that influence longevityPersonalized healthy living programs and the four pillars for longevityChanging lives and following up to ensure long-term healthWhy there is no "magic pill"Mindfulness, meditation and bespoke physical exercise modifications The eye-opening impact of Covid on the business of wellness and the long term implications for healthcareThe lasting impact of a week's intensive therapies?Implementing  long-term health programs though CLP hubs around the world. The importance of lifestyle changes and work/life balance. Morning routines and daily health. Taking the long view and imagining the wellness conversation for decades to come. “This episode is brought to you in association with Clinique La Prairie, the award-winning spa-clinic - and pioneering health and wellness destination - nestled on the shores of Lake Geneva in Montreux, Switzerland. Combining preventative medicine with bespoke lifestyle and nutrition plans, Clinique La Prairie offers a holistic approach to living fuller, healthier and longer lives.”The Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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Apr 28, 2021 • 39min

Kathleen O'Brien: Stop and smell the roses

The art of growing old, gracefully and purposefully, preferably in rude health, is unique to us all. The journey, with its many twists and turns, involves myriad emotions, adventures and challenges. But Kathleen O'Brien says the process has been somewhat hijacked by society's growing disrespect for the elderly. In her book, Reclaim Your Right To Grow Old, the American writer and broadcaster explores the history of attitudes towards aging and suggests that society's fevered quest for longevity is misguided.  In this LLAMA podcast conversation with Peter Bowes, Kathleen argues that the happiness to be found in aging is being undervalued; that the eccentricities of older people should be celebrated and the joy of smelling the roses more often enjoyed. Recorded: April 12, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:Kathleen's voice was once very familiar to Americans  - how come? Approaching the "sad ride on the down slope" and discovering a new way to look at aging. Exploring the history of aging and the attitudes of ancient cultures, especially towards 'elders.'What the location of graveyards tells us about changing attitudes towards older people and deathIs 'keep busy, keep active' necessarily a positive message, as people age. The 'reclaim your right to grow' old philosophyEmbracing the eccentricities aging - being free to be who we want to be. Smell the roses and worry lessDeath anxiety, spirituality and changing attitudes as we ageThis episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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Apr 21, 2021 • 39min

Jason Karlawish: What next for Alzheimer's disease?

There has been "spectacular" progress in recent years in the understanding and treatment of Alzheimer's.  The progressive disease, which is the most common cause of dementia, a late-in-life decline in memory and cognitive ability, afflicts 50 million people around the world. Taking family members and other carers into account, that number increases exponentially.  The condition, for which there is currently no cure,  amounts to a modern day crisis, for all involved. In this episode of the LLAMA podcast, Dr Jason Karlawish, a gerontologist and professor of medicine and medical ethics and senior fellow of the Center for Bioethics at the University of Pennsylvania, says significant gains are being made with therapeutic treatments, but many hurdles remain.  The author of The Problem of Alzheimer's: How Science, Culture and Politics turned a Rare Disease into a Crisis, also argues that Alzheimer's is disease of our identity and a condition that raises fundamental, moral questions about what it means to lead a good life. Recorded: March 30, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:The difference between dementia and Alzheimer's disease.How can dementia be distinguished from the 'normal course of aging?"The work of the Penn Memory Center, with patients and their loved ones. Explaining medicine in the 'real world,' through the stories and experiences of people.Why patients and caregivers are the best teachers. Distinguishing between disease and disability. How stigma haunts the lives of people with dementia. Defining Alzheimers as once a rare disease, now a crisis. The "spectacular progress in science," dealing with Alzheimer's. "Living' with Alzheimer's rather than relying on drugs. Why is the risk of demential declining? The crisis of good quality care for Alzheimer's patients in the U.S.Regular exercise and a heart healthy diet to maintain good brain health.  Red wine too? This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
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Apr 14, 2021 • 36min

Lisa Levine: Embracing midlife without a crisis

Turning fifty can be a wrenching experience for some people.  Others discover that it is their sixtieth birthday that conjures up disturbing emotions. There is no doubt that big birthdays focus the mind on the aging process and what is often described as a midlife crisis.  But should we fear the passage of time?  Lisa Levine is a life coach and the author of Midlife No crisis, an insightful and entertaining exploration of the years that signpost our lives.  In this LLAMA podcast conversation with Peter Bowes, Lisa explains why we should embrace "transformative" periods, instead of dreading them, and how the advancing years can propel us in a "more fulfilling direction," with excitement and optimism. Recorded: April 5, 2021 | Read a transcript and show notes at the LLAMA podcast website.Topics covered in this interview include:When does mid-life happen and why is it associated with a crisis for some people.Pre-empting a mid-life crisis When the meaning  of life becomes more important that just doing a job. The difference between turning 50 and 60?Leaving Hollywood and the entertainment business for a new calling - something deeper with more meaning. Becoming a life coach and "walking the talk." Dealing with health obstacles and fertility issues and discovering alternative therapies. Do men and women face the same mid-life issues? How our backgrounds and life experiences mold our lives and attitudes toward aging. Discovering the perks on midlife, wisdom and putting space between negative thoughts.The value of friends and community in dealing with the aging process - knowing that you're not alone. Social media - compare and despair. Avoiding the rabbit holes. The privilege that is aging. This episode is brought to you in association with JUVICELL, the all-in-one longevity supplement that contains 10 key ingredients shown to have a positive impact on healthspan, as validated by scientific studies. To find out more, visit juvicell.comThe Live Long and Master Aging podcast shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts   SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice.  If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

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