the goop podcast

Tig Notaro, comedian, writer, actor, and producer of the Oscar-nominated documentary Come See Me in the Good Light, reflects on friendship, illness, and mortality. She discusses making an intimate film about Andrea Gibson’s final year, the interplay of humor and heartbreak, and how art and comedy shaped meaning and resilience in the face of loss.

Gwyneth sits down with Amanda Knox to reflect on life after global scrutiny—rebuilding her identity, processing the years she lost, and the extraordinary strength it takes to choose forgiveness. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

Andrew Huberman, neuroscientist and Stanford professor who translates brain science into practical tools. He tackles protein myths, peptides and their risks, the gut microbiome’s role in inflammation, and how sunlight, sleep, and simple habits shape nervous-system regulation. Short, science-forward conversations about emerging therapies and everyday biology.

Emma Grede, founder of Good American and co-founder of Skims, is an investor and entrepreneur who built inclusive, culturally influential fashion brands. She talks about betting on herself, product instincts and risk-taking, trend forecasting and making demand, leadership and hiring rules, gratitude rituals and scaling mentorship.

Emily Hickey, marketing strategist who turns instinct into brand codes, talks about crafting personal rules and reinvention. Short takes cover defining prescriptive codes, building non-negotiables, using clothes and decor as self-expression, and translating mood boards into signature style. The conversation centers on discipline, identity, and designing a consistent personal or brand DNA.

Mike Blue, CEO of HistoSonics, leads development of histotripsy, a noninvasive focused-ultrasound method to destroy tumors. He explains how the tech works, the FDA-cleared liver treatment, and plans for kidney, pancreas, and other targets. They discuss patient comfort, quality-of-life benefits, immune effects, and where this approach might fit into cancer care.

Dr. Paul Savage, integrative medicine physician and founder of MD Lifespan, who pivoted from ER care to longevity and advanced detox, discusses therapeutic plasma exchange. He explains how plasma carries toxins, why modern exposures overwhelm clearance, and a protocol combining serial TPE with supportive nutrients. The conversation covers reported lab reductions, symptom improvements, safety considerations, costs, and practical toxin-avoidance tips.

Chelsea Hirschhorn, founder and CEO of Frida who built a candid parenting and women’s health brand, talks about the unseen chapters of motherhood. She covers how Frida started with the noseFrida, expanding from baby care to mother care, censorship battles over realistic birth content, gaps in fertility education, and grieving pre-parent identity. Multiple short, honest conversations about readiness and asking for help.

Scott Galloway, entrepreneur, NYU professor, and bestselling author, discusses his book Notes on Being a Man and why boys and young men are struggling. He explores brain development, school and economic shifts, dating dynamics, digital addiction, vocational training, rites of passage, and caregiving as part of modern masculinity.

In a candid chat, makeup artist and beauty entrepreneur Bobbi Brown shares her journey from founding Bobbi Brown Cosmetics to launching Jones Road Beauty. She discusses the importance of self-worth and the continual process of reinvention through various life stages. Bobbi delves into childhood influences on her confidence, balancing work and leisure, and the challenge of letting go as a leader. Emphasizing self-compassion and pursuing passions, she also reflects on the joys of empty nesting and advocates for embracing life's curiosities with a 'why not?' attitude.