

In the Know with Amol Sarva
Amol Sarva
Amol Sarva's series with changemakers and innovators in longevity, tech, and ideas
Episodes
Mentioned books

Aug 16, 2024 • 37min
How food becomes energy and the view from sports nutrition on metabolism with Professor Derek Huffman of Einstein
The journey from food through digestion to your liver to energy stores and metabolizing work is the obsession of sports science - and hugely relevant to metabolic health overall. Let's get this perspective from research professor Derek Huffman at Einstein Medicine in New York.
Dive into metabolic health!

Aug 16, 2024 • 45min
Food as medicine with physician and founder Jeff Alfonsi
The different foods we eat and how they interact make a huge difference in disease progression, weight, and everything else. Dr. Jeff Alfonsi is a practicing physician for years, and chief medical officer of RxFoods which is designed to identify what you are eating and how to get better results.
Metabolic Health is the biggest medical breakthrough of the moment. Dive in.

Aug 1, 2024 • 30min
Pro biotics, pre biotics, and what your digestive system knows with Maya Kaelberer, Ph.D.
Let's understand an overlooked dimension of the weight loss revolution underway -- the microbes in the digestive system themselves, potentially where GLP-1s come from in the first place. Duke's gut biome expert Maya Kaelberer gives us a guide.
Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

Jul 31, 2024 • 51min
Metformin, Rapamycin, the cellular mechanisms at the cutting edge of weight loss and longevity with Matt Kaeberlein, Ph.D.
Metabolic Health is the biggest medical breakthrough of the moment
Let's understand the cellular mechanisms and some of the most promising and widely used drugs in the world with one of the foremost researchers in the field, Matt Kaeberlein, formerly of University of Washington and now founder of longevity company Optispan

Jul 30, 2024 • 47min
Bariatric surgery, the gut biome, and the interactions that create weight loss with surgery and nutrition professor Randy Seeley, Ph.D. at Michigan
Metabolic Health is the biggest medical breakthrough of the moment
Mapping all the ways the GLP-1 drugs like Ozempic do and might work means we need to understand the biome and the efficacy of surgical interventions. We talk to Professor Randy Seeley who directs University of Michigan's Nutrition Obesity Research Center

Jul 29, 2024 • 43min
Understanding blood sugar and insulin with world leader on diabetes Dr. John Buse of UNC
Metabolic Health is the biggest medical breakthrough of the moment
Dr. John Buse has been at the forefront of diabetes research and endocrinology since before the first GLP-1 results started to become known. He studies the body's systems that seem to be at the core of how Ozempic and diabetes operate -- let's learn about the endocrine system and map out these system-level interactions

Jul 26, 2024 • 37min
How weight loss works with Yale’s Dr. Waj Mehal
Metabolic Health is the biggest medical breakthrough of the moment
We have one of the world's experts on the liver - the place your body stores lots of energy from food, and distributes it onward to other systems, Dr. Waj Mehal of the Yale School of Medicine.
We lay out a map of the systems in digestion and metabolism, weight loss and exercise -- plus the different pathways that GLP-1s like Ozempic are using, and what else expected or unexpected is going on in our bodies

Jul 25, 2024 • 45min
How Ozempic works and what else could revolutionize metabolic health with James Peyer, Ph.D. of Cambrian Bio
Metabolic Health is the biggest medical breakthrough of the moment
Get up to speed on the cellular biology with a fantastic overview from PhD scientist and founder of breakthrough pharma platform Cambrian Bio

Aug 8, 2023 • 52min
Alex Zhavoronokov from In Silico, the AI longevity drug discovery giant, on the revolution now and tomorrow

Jul 10, 2023 • 47min


