In the Know with Amol Sarva

Pablos built one of the first decentralized money networks, the first experimental Blue Origin rockets, one of the first handheld computers, invented 1000s of new patents with Nathan Myhrvold, and most recently launched a deeptech venture firm called Deep Future. And now, on July 12, expect his book: "Deep Future". -- Pablos Holman and Amol on Deep Future Amol Sarva: [00:00:00] On today's episode, I'm excited to have my pal, Pablo Coleman from the future. Are we rolling? We are rolling. Right on. Bob, are we rolling? Bob? And we're gonna talk about, I don't know I think we should talk about a little bit of origin story before we get to the fund and the new book that's coming out. And I'm excited to be the first interviewer Yeah. That you've chosen to speak to  Pablos Holman: about your freshly. Finalized manuscript. We're gonna turn the tables. I'm gonna have you on my podcast sometime too. Yeah, that'd be great. Apparently you have, we should  Amol Sarva: have done right now, apparently you have hundreds  Pablos Holman: of listeners, I dunno, hundreds or thousands here. Here. Not hundreds of thousands  Amol Sarva: Here on this podcast we have the two of us who will listen to it be recorded. Hey, I'm  Pablos Holman: cool with that. I once had a radio show in Alaska and we had a full studio and we broadcast. But we had no antenna. The station had no antenna, but we had 24 hour a day broadcasting. So imagine like how esoteric and weird the DJs for a radio station are that have no listeners. Yeah. Like we had the best [00:01:00] parties.  Amol Sarva: Yeah. Wow. Then I guess let us begin then with the origin stories. Cool. You were born in Alaska? Apparently. I was born in  Pablos Holman: Alaska. Yeah. It's hard to find an Alaskan who's escaped from Alaska, but I'm one of 'em, I've literally never met anyone who's from Alaska. I know. Yeah. They make it about as far as Seattle and then they really feel like they've traveled and then they usually go back to Alaska. Very few Alaskans make it this far. So you made it to the great capital of Seattle across the I left Alaska, I went to Silicon Valley and then ended up, yeah, after the.com collapse, I retreated to Seattle. And but that was good. And Seattle was really good for a long time. Now I'm over it.  Amol Sarva: I, part of part of what's really cool about that experience, or at least that I quite admire, is you got to work with some of the real. Intellectual rock stars of the tech world. Certainly yeah, in the, I guess it would've been the two thousands, roughly. Yeah.  Pablos Holman: Yeah. After Silicon Valley I went to work I went to Seattle and I started Blue Origin or helped start Blue Origin with Jeff Bezos. Yeah. [00:02:00] And so that was great for me and an inflection point where I took all of the experience of bringing computer technology to life and trying to use the computers to bring other technologies to life. And so that's what. What I think of as deep tech.  Amol Sarva: Yeah. But how'd you even so what was the Silicon Valley tour of duty then that I  Pablos Holman: started out computer hacking when I was a kid. So when I was in Silicon Valley, it was really about trying to, use the, that skillset to bring new technologies. And, in the late, in the, like late eighties and early nineties, it was really just take computers into every industry for the first time. But then, once we started putting Muggles on the internet in 94, then I realized, oh shit, this is not gonna go ve

So you missed the all-day all-science+technology collection of superstars gathered by LifeX and Bits in Bio at Fenwick in New York? Wondering what the frontiers of foundation models in bio, longevity, startups and more are pushing? Now you can use the cheat code and just listen to this synopsis of the big highlights and discussion points.

Jim, founder of Juvenescence, old China and Russia hand, and investor in our fund LifeX sends me an email every morning with lots of attachments that he read that morning. Here's what he's been thinking about the last month.

Read the post here: https://amol.sarva.co/%f0%9f%90%8c-kohei-saitos-slow-down-de-acc-manifesto/

I gave a talk in Stockholm last year, that I asked these robots to discuss. Hope you enjoy it. This doesn't look LIKE me but it does sort of resemble what I could possibly look like. It was the first draft. Some better prompting got us to the final image.

The legendary tech beat reporter is back with a team effort newsletter covering some of the most interesting people in tech. Listen in to hear what he's been thinking about over the last 10 issues.

We analyzed the 1,000s of companies we're watching and investing in at LifeX. We looked at every update email from every CEO and every conversation notes from every team member. And we made hits outlook for the year ahead, automagically. (Excuse robo-typos.) Enjoy!

We synthesized the dozens of outlook reports from Wall Street analysts on health, biopharma, and related trends. Listen in to Amolbot (an automated Amol) and co-hosts.

We synthesized the dozens of outlook reports from Silicon Valley observers of techbio for AI x Health startups and trends. Listen in to Amolbot (an automated Amol) and co-hosts.

Dr. B is an expert on gut health and shouting its power from the rooftops, both in his practice and writings but also through the company Zoe where he is US medical director. Some interesting news about coffee in this one. Metabolic Health is the biggest medical breakthrough of the moment. Dive in!