Health Optimization Medicine Podcast

In this episode of the Smarter Not Harder Podcast, our guest Dr. Kiran Krishnan joins our host Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: What are the most exciting clinical developments in the field of gut microbiota and probiotic supplementation? How do outer membrane vesicles violate the dogma that bacteria and human cells should not communicate directly? Why is the gut microbiota now considered an organ in the body that is postnatal, or an organ that grows right after birth? Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa. He left University research to take a position as the U.S. Business Development and Product Development lead for Amano Enzyme, USA. Amano is one of the world's largest suppliers of therapeutic enzymes used in the dietary supplement and pharmaceutical industries in North America. Kiran also established a Clinical Research Organization where he designed and conducted dozens of human clinical trials in human nutrition. What we discuss: (0:00:04) - Gut microbiota and probiotics revolution (0:17:21) - Gut microbiota and organ function (0:25:30) - Bifidobacterium longum's impact on mood (0:31:22) - Gut bacteria and brain development (0:45:55) - Microbiome and covid-19 risk factors (0:51:41) - Inter-kingdom communication and implications (1:12:09) - Probiotics' impact on inflammation and microbiome (1:17:19) - Microbiome analysis in clinical trials (1:24:02) - Microbiome's role in addiction and autoimmunity (1:37:30) - Microbiome functionality and redundancy (1:42:10) - Foundational organisms and future projects (1:55:10) - Advancing phytoceuticals and extraction processes (2:11:47) - Advancements in gut microbiota science Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Kiran Krishnan: Instagram: @kiranbiome Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Tommy Wood joins our host Boomer Anderson to give one-cent solutions to life's $64,000 questions that include: What types of markers should you be testing, and when are they necessary? What can those in the general population be doing to optimize their health, specifically minimizing cognitive decline and physical decline as they age? What do elite level athletes and elite level professionals do differently? Dr. Tommy Wood is a Senior Fellow in the Pediatrics Department at the University of Washington, and Chief Scientific Officer of Nourish Balance Thrive, an online-based company using advanced biochemical testing to optimize performance in athletes. He is currently President-elect of Physicians for Ancestral Health, he is a director of the British Society of Lifestyle Medicine and the Icelandic Health Symposium, and is on the scientific advisory board of Hintsa Performance. Tommy has also coached and competed in multiple sports including rowing, CrossFit, powerlifting, and ultra-endurance racing. Alongside his career in medicine and research, Tommy has published and spoken on multiple topics surrounding functional and ancestral approaches to health, including examining the root causes of multiple sclerosis and insulin resistance. What we discuss: (0:00:04) - Optimizing health and performance (0:12:53) - Improving infant and child development (0:22:39) - How dancing and video games impact brain development (0:29:25) - Development and health in children (0:42:20) - The importance of comprehensive blood tests (0:47:33) - Supplements, testing, and anti-aging (0:57:19) - NAD levels, lifestyle factors, and exercise (1:10:27) - The environment's impact on the human body (1:19:00) - Stimulating brain function and behavior change Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Tommy Wood: Website: https://www.drtommywood.com/ Instagram: @drtommywood Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Ted Achacoso joins our host Dr. Scott Sherr to give one-cent solutions to life's $64,000 questions that include: What is GABA, and why do we need it? How is GABA synthesized? What are some of the conditions and syndromes that are related to GABA deficiency? Dr. Ted is the founding pioneer of Health Optimization Medicine and Practice, a 501(c)3 nonprofit organization dedicated to helping doctors and practitioners learn how to optimize for health rather than treat disease. He is also the founder of Smarter Not Harder Inc, makers of Troscriptions. He went to med school at the age of 18, and is trained in interventional neuroradiology, toxicology and pharmacology. He is also trained in anti-aging medicine, nutritional medicine, and is an expert in hormone balancing. What we discuss: (0:02:14) - Understanding GABA (0:14:21) - GABA receptors and their subtypes (0:24:03) - GABA's role in brain function (0:35:20) - Sleep-inducing substances and their effects (0:41:33) - Health optimization and balanced living Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Ted Achacoso: https://homehope.org Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Susan Rossell joins our host Jodi Duval to give one-cent solutions to life's $64,000 questions that include: What is psilocybin, and what effects does it have on the brain? What are the potential risks of psilocybin, and what could go wrong during psilocybin experiences? What is the connection between psilocybin and body dysmorphic disorder? Dr. Susan Rossell is a leading clinical neuropsychologist and researcher based in Australia. She is widely recognized for her contributions to the field of cognitive neuroscience, neuropsychology and mental health. As a professor of cognitive neuropsychology and director of the Brain and Psychological Sciences Research Center at Swinburne University of Technology, Dr. Rossell's expertise lies in understanding the neural mechanisms of underlying mental health conditions such as schizophrenia and bipolar and anxiety disorders. What we discuss: [00:00] Body dysmorphia is a difficult mental illness to treat with no specific interventions. [06:35] Psilocybin trials for depression and body image disorders [12:39] Psychedelic-assisted psychotherapy opens up new ways of thinking [18:46] Serotonin causes a flush through the system, making us more responsive to the world, but can also cause anxiety and stress. [24:49] Psychedelic treatment safety data is insufficient for minors [30:27] Psychedelic therapy in Australia requires experienced professionals and research approval. [36:11] Rolling out interventions without enough data is concerning [42:22] Body dysmorphic disorder (BDD) is a growing concern with no effective interventions. [48:04] BDD in children is increasing due to excessive screen time and lack of outdoor activities. [53:37] Living smarter not harder involves simple things like going to the beach and creating brain chemicals naturally. [59:16] Psilocybin's potential in transforming mental health therapies Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Susan Rossell: Twitter: @rossellsusan LinkedIn: Susan Rossell Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Ted Achacoso joins our host Boomer Anderson to give one-cent solutions to life's $64,000 questions that include: What are some things that are commonly misunderstood about the mitochondria? How are common drugs in the anti-aging world poisoning the mitochondrial complexes? Why is the holobiont perspective particularly important for the mitochondria? Dr. Ted is the founding pioneer of Health Optimization Medicine and Practice, a 501(c)3 nonprofit organization dedicated to helping doctors and practitioners learn how to optimize for health rather than treat disease. He is also the founder of Smarter Not Harder Inc, makers of Troscriptions. He went to med school at the age of 18, and is trained in interventional neuroradiology, toxicology and pharmacology. He is also trained in anti-aging medicine, nutritional medicine, and is an expert in hormone balancing. What we discuss: [00:08:22] Intermittent fasting and ketogenic diets affect autophagy and mitochondrial biogenesis [00:20:17] The body uses signaling molecules to sense the body's energy needs [00:24:22] Mitochondria decrease in population and acquire mutations as we age [00:31:18] Mitochondrial haplotypes can vary based on geographic location and climate [00:39:44] Keeping cells in network control prevents proliferation [00:42:07] For any supplement to work, it has to pass the double membranes of the mitochondria [00:50:16] Testing is necessary to recommend lifestyle modifications objectively [01:00:04] Supplementation can correct imbalances in the mitochondria Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Ted Achacoso: https://homehope.org Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Janet Schloss joins our host Jodi Duval to give one-cent solutions to life's $64,000 questions that include: What are some of the intricacies of the endocannabinoid system, and how can it impact our health? How can medical cannabis be used in the treatment of chronic disease and conditions? What are the challenges of designing research studies around medical cannabis? Dr. Janet Schloss is the Clinical Research Fellow at the National Centre for Naturopathic Medicine at Southern Cross University. Janet is an accomplished researcher with extensive experience in coordinating clinical trials. In addition to her academic career, Janet is a practicing clinical nutritionist and naturopath with over 20 years of experience. Following the completion of her doctorate in 2015, Janet has focused her research on supporting people who have cancer through studying the use of complementary medicine to assist side effects of cancer treatments. Janet has completed a number of groundbreaking studies and has over 60 publications, and now focuses a lot of her research on medical cannabis. What we discuss: [00:00] Medical cannabis has gained recognition as a powerful tool in healthcare. [07:03] Researching medicinal cannabis for GBM [13:22] Medicinal cannabis has potential but is not right for everyone [19:15] Understanding the different cannabinoids and their effects [24:59] Medical cannabis has promising applications in chronic diseases, stress, anxiety, and inflammation. [30:42] Exciting opportunities in cannabis research for neurological conditions [36:28] Cannabis products can aid in chemotherapy and adjunct treatment [41:54] Educating patients on medicinal cannabis is crucial [47:24] Titration of cannabis is individualized and requires slow and steady dosing. [52:45] Timing and proper dosage are crucial for effective cannabis treatment [58:36] Antioxidants are not what we think they are Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Janet Schloss: https://www.janetschloss.com/ LinkedIn: https://www.linkedin.com/in/janet-schloss-9a30a48/?originalSubdomain=au Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Alex Rosenberg joins our host Boomer Anderson to give one-cent solutions to life's $64,000 questions that include: What are the definitions of scientism and naturalism? Is there such a thing as free will, and if so, what implications does it have on the search for purpose in life? What is nice nihilism? Alex Rosenberg is an American philosopher and novelist. He is the R. Taylor Cole Professor of Philosophy at Duke University, and is well known for contributions in the philosophy of biology, as well as the philosophy of economics. He has also written several books, including "The Atheist's Guide to Reality: Enjoying Life without Illusions" and "Philosophy of Science: A Contemporary Introduction." What we discuss: [00:00] Fundamental laws of physics are time symmetrical [06:53] Naturalism requires letting go of everyday reality and embracing science. [13:43] The second law of thermodynamics governs the emergence of organized adaptive systems. [20:31] The content of conscious thought is an illusion. [27:25] Self-help industry is exploiting people's credulity. [34:10] Our continual dissatisfaction is a result of natural selection. [40:58] Do we have free will? [47:34] Nice nihilism is the doctrine that most of us behave in ways that are satisfying to the emotional responses of others. [54:10] Living in the moment may not lead to happiness [1:00:53] Seek professional advice driven by science for living smarter. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Alex Rosenberg: https://alexrosenbergbooks.com/ https://scholars.duke.edu/person/alexrose Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

Dr. Mark Gordon, an expert in traumatic brain injury, PTSD, and hormonal optimization, discusses the link between stress, cortisol, and brain injury. He also highlights the importance of vitamin D for the immune system and testosterone production. Balancing all hormones is crucial for overall health. Topics include: PTSD and TBI connection, significance of hormone optimization, reducing brain inflammation, addressing inflammation in clinical practice, role of testosterone in brain function, and optimizing growth hormone production.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Brad Leech joins our host Jodi Duval to give one-cent solutions to life's $64,000 questions that include: What are the benefits of a healthy microbiome and how do we measure this? What does the gut microbiome do for us, and how does the microbiome interact with systemic health? What are some new advancements surrounding the microbiome in recent years, and what does this mean or change for us clinically? Dr. Brad Leech is a PhD-qualified Clinical Nutritionist specializing in chronic autoimmune conditions and complex gastrointestinal disorders. He provides complete and personalized care to his patients using functional nutrition, integrative medicine and holistic wellness. After entering the profession in 2008, Brad has taught and developed subjects at leading universities and conducted research on intestinal permeability, autoimmune disease management and food-based probiotics. Brad is the Lead Clinical Educator and co-creator of Co-Biome, where his expertise in gastrointestinal healthcare enables him to translate the latest science on the gut microbiome into practical clinical applications. In addition to his research, and working with patients, Brad offers practitioner support through his mentoring program Brad's Brainiacs. What we discuss: [00:00] A healthy microbiome is essential for optimal health and can reduce the risk of chronic diseases [07:40] Diversity in diet is key for a healthy microbiome [14:16] The gut microbiome produces metabolites that impact systemic health [21:10] Microbiome diversity and production of beneficial compounds are linked to various health conditions [27:31] Advanced sequencing methods allow for a comprehensive understanding of the microbiome. [34:21] Metagenomics can identify 28,000 bacterial species and their functions [40:55] Personalized medicine is the new approach to treating dysbiosis [46:54] Reduce LPS-producing bacteria through prebiotic fiber, bovine colostrum, and reducing saturated fats [53:16] Increase butyrate production with resistant starch and diverse fiber [59:41] Recommended daily fiber intake is around 30 grams for females and 38 grams for males Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Brad Leech: Website: https://drbradleech.com/ Instagram: @drbradleech Twitter: @drbradleech LinkedIn: https://www.linkedin.com/in/drbradleech/ Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Scott Carney joins our host Boomer Anderson to give one-cent solutions to life's $64,000 questions that include: How does something go from an idea, to a story, to a book? How can one go wrong in the pursuit of what is otherwise known as a noble path? What is the relationship between the dark side of spirituality and the pursuit of enlightenment? Scott Carney is a New York Times bestselling author, anthropologist and investigative journalist. His works include What Doesn't Kill Us, The Vortex, The Wedge, The Red Market and The Enlightenment Trap. Carney was a contributing editor at Wired for five years and his writing also appears in Mother Jones, Men's Journal, Playboy, Foreign Policy, Discover, Outside and Fast Company. His work has been the subject of a variety of radio and television programs, including on NPR and National Geographic TV. What we discuss: [00:00] The rule of social media is the same as the rule of improv [06:38] The moment that instigated the majority of what Scott has written [17:43] Spirituality can be a tool to become a good person, but it can also lead to spiritual bypassing [23:32] Exploring the dangers of spiritual journeys and gurus [39:58] The authenticity of Eastern spiritual traditions is often overestimated [50:57] Beware of warning signs in spiritual and health communities that may indicate cult-like behavior [01:13] The problem with health gurus and their untested ideas [1:06:49] The potential dangers of the Wim Hof method [1:12:02] The dangers of blindly following gurus and influencers Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Scott Carney: https://www.scottcarney.com/ Instagram: @sgcarney Twitter: @sgcarney Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.