
Lynne Chou O’Keefe
Founder and Managing Partner of Define Ventures, an early-stage health tech investment firm with deep experience in digital health and venture capital; known for investments in companies like Hims & Hers, Livongo, and Evolent and for expertise on how technology and ethics intersect in healthcare.
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Feb 9, 2026 • 44min
375: How AI Is Changing Healthtech Investing, According to Define Ventures’ Lynne Chou O’Keefe
Lynne Chou O’Keefe, founder of Define Ventures and early healthtech investor, talks about why fragmented systems make AI most useful in admin and workflows. She outlines three AI adoption phases, explores ethics and human-in-the-loop safeguards, and explains how value-based care and consumer expectations reshape healthcare delivery.


