AI and the Future of Work: Artificial Intelligence in the Workplace, Business, Ethics, HR, and IT for AI Enthusiasts, Leaders and Academics 375: How AI Is Changing Healthtech Investing, According to Define Ventures’ Lynne Chou O’Keefe
Feb 9, 2026
Lynne Chou O’Keefe, founder of Define Ventures and early healthtech investor, talks about why fragmented systems make AI most useful in admin and workflows. She outlines three AI adoption phases, explores ethics and human-in-the-loop safeguards, and explains how value-based care and consumer expectations reshape healthcare delivery.
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Pacemaker Surgery Sparked Her Calling
- Lynne's aha moment came watching a pacemaker switch-out in a surgical suite and seeing archaic workflows.
- That contrast—advanced implants but paper-based processes—drove her into healthcare innovation.
Build With A V1→V2→V3 Vision
- Use a V1→V2→V3 product vision: start with a wedge, evolve to a platform, then become a dominant system changer.
- Frame ROI and strategic partnership early to break through buyer noise in healthcare.
Speak Strategics’ Language
- Prioritize defining partnership by speaking the language of strategics and demonstrating clear ROI.
- Target being a top-three priority for buyers to overcome noise and win adoption.