Colleen Cutcliffe

Colleen Cutcliffe, a molecular biology expert and co-founder of Pendulum Therapeutics, dives into the fascinating world of the microbiome. She explains how our gut health impacts overall well-being and emphasizes the importance of a high-fiber diet. Colleen discusses probiotics, prebiotics, and innovative treatments like fecal microbiota transplants for various health issues. She also sheds light on antibiotic effects on microbiomes and the emerging role of specific strains like Acromantia in managing conditions like diabetes. A must-listen for health enthusiasts!

Colleen Cutcliffe, a biochemistry and microbiology PhD and CEO/co-founder of Pendulum Therapeutics, built targeted microbiome interventions. She discusses how sequencing unlocked microbiome science. She shares animal microbiome tales, why fecal transplants cure C. diff, the role of Akkermansia and gut barrier analogies, microbes that stimulate GLP-1, and why strains plus fiber matter for lasting change.

Dr. Colleen Cutcliffe, CEO of Pendulum Therapeutics and an expert in biochemistry, reveals a groundbreaking probiotic that stimulates natural GLP-1 production. She shares why traditional GLP-1 drugs like Ozempic are being challenged by this new approach. Listeners learn about impressive trial results showing reduced food cravings and the complexities of probiotic production. Colleen also discusses the importance of keystone strains in the microbiome and the potential benefits for managing obesity and diabetes.

This week’s conversation is with Dr. Colleen Cutcliffe, the CEO and Co-Founder of Pendulum Therapeutics.Colleen’s extensive background includes a doctorate in Biochemistry and Molecular Biology from Johns Hopkins University, and over 20 years of experience managing and leading teams in biotech, pharma, and academia.In 2013, Colleen left her position as Senior Manager of Biology at Pacific Biosciences to start Pendulum, a company on a mission to improve health through first of its kind research and development in the gut microbiome.Pendulum’s next generation probiotics are pioneering ways for people to transform their health and wellness by unlocking the power of the gut microbiome.I’ve been studying gut health and the microbiome for a long time now, and it’s clear that Pendulum is on the forefront of creating meaningful change for people.I was fascinated to learn more about the topic from Colleen, and I hope you leave this conversation with a better understanding of the gut microbiome, and some applied insights on how improving your gut health can improve your life._________________Subscribe to our Youtube Channel for more powerful conversations at the intersection of high performance, leadership, and meaning: https://www.youtube.com/c/FindingMasteryGet exclusive discounts and support our amazing sponsors! Go to: https://findingmastery.com/sponsors/Subscribe to the Finding Mastery newsletter for weekly high performance insights: https://www.findingmastery.com/newsletter Download Dr. Mike's Morning Mindset Routine! https://www.findingmastery.com/morningmindsetFollow us on Instagram, LinkedIn, and X.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Wild Health Podcast, we sit down with Colleen Cutcliffe, CEO and co-founder of Pendulum, to explore the power of the microbiome for optimal health. We learn about the significance of keystone bacteria, probiotics' impact on chronic illness and metabolic health, and practical tips for incorporating Akkermansia into your routine. Discover the relationship between high fiber diets, polyphenols, and increasing Acromancia levels, as well as the philosophy of selling directly to consumers and the limitations of FDA approval.

Colleen Cutcliffe, Ph.D., a biochemist, microbiologist, and co-founder of Pendulum Therapeutics, discusses how improving your gut microbiome can enhance metabolism. She explains the importance of Akkermansia, a beneficial bacterium, in boosting GLP-1 levels naturally. Listeners learn about gut-supporting foods, the impact of diet on microbial diversity, and the consequences of antibiotics on gut health. Cutcliffe also touches on the future of microbiome science, including exciting advancements like next-generation probiotics and fecal transplants.

Colleen Cutcliffe, CEO and co-founder of Pendulum Therapeutics, dives into the fascinating world of gut health. With her impressive background in biochemistry, she explores the gut-brain connection, revealing how our gut impacts mood and metabolism. Colleen simplifies the roles of probiotics, prebiotics, and the often-overlooked Akkermansia strain, crucial for digestive health. She also discusses the significant effects of antibiotics on our microbiome and offers strategies for recovery, emphasizing nutrition as key to a thriving gut.

Colleen Cutcliffe, CEO and Co-founder of Pendulum, draws on her extensive background in microbiome science to unravel the mysteries of GLP-1. She discusses how GLP-1 regulates appetite and curbs cravings, paving the way for healthier eating habits. The fascinating connection between gut bacteria and metabolic health takes center stage, with a focus on specific probiotic strains like Akkermansia. Colleen also shares insights on hydration's role in health and the challenges of accurately measuring gut bacteria levels.

Colleen Cutcliffe, Ph.D., molecular biologist and biochemist, is the CEO and co-founder of Pendulum, focused on gut health. She shares groundbreaking research on Akkermansia muciniphila, a beneficial gut bacteria linked to weight management and metabolism. Listeners learn how this keystone strain can enhance gut lining and immune function. Colleen also discusses dietary impacts, emerging probiotics, and offers insights on how to boost Akkermansia for better health outcomes, making gut health an innovative route to improved well-being.

Dr. Colleen Cutcliffe, microbiome scientist and Pendulum co-founder, translates gut bacteria research into practical products. She explores how microbes shape metabolism, GLP-1 signaling, cravings, hormones and perimenopause. Conversation highlights next-generation probiotics, resilience-building strategies, travel and antibiotic impacts, and sensible ways to start rebuilding gut health.