The Jesse Chappus Show 693: Weight Gain Isn't About Calories — It's Insulin | Dr. Jason Fung
33 snips
Feb 24, 2026 
Dr. Jason Fung, nephrologist and bestselling author who studies fasting and insulin, breaks down why hormones—especially insulin—drive fat, not calories. He compares food forms, explains how meal timing, snacking, and ultra‑processed foods alter insulin, and offers practical low‑insulin tactics like meal order, resistant starch, and fasting. He also covers hormones that set defended body weight.
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Three Types Of Hunger Drive Eating Behavior
- Hunger has three distinct drivers: homeostatic (physiologic), hedonic (pleasure), and conditioned (environmental).
- Identifying which drives your eating determines the treatment: hormones, abstinence/mindfulness, or counterconditioning respectively.
Find The Why Before Telling People To Eat Less
- Do diagnose the why behind overeating before prescribing 'eat less' because calorie advice ignores root causes like addiction, stress, or conditioning.
- Treat alcoholism by addressing addiction; treat overeating by addressing its specific drivers.
Body Fat Is A Hormonal Thermostat
- Body fat is controlled by a hormonal thermostat, not just calories in versus calories out.
- Insulin raises the thermostat to store fat while GLP-1, sympathetic tone, and other hormones lower it, explaining metabolic adaptation during weight loss.
