The End of the SDR? AI and the Future of Go-to-Market with Amanda Kahlow, Founder and CEO of 1mind

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Mar 5, 2026

Amanda Kahlow, Founder and CEO of 1mind and former Sixth Sense founder, builds AI "superhumans" that run large parts of the go-to-market lifecycle. She discusses AI evolving from caregiver tech to running demos and qualifying buyers. Conversations cover how AI changes handoffs, collapses onboarding timelines, and leaves humans for the nuanced final mile.

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INSIGHT

How Caregiver AI Became Sales Superhumans

Amanda Kahlow repurposed AI built to clone caregivers for Alzheimer's into sales-focused “superhumans” that can hold deep, always-on conversations.
She negotiated spinning the tech into OneMind so agents could run demos, qualify buyers, and build business cases instantly.

INSIGHT

Superhumans Span The Full GTM Lifecycle

OneMind builds lifecycle superhumans that do far more than AISDRs, including solutions engineering, demos, quotes, onboarding, and CSM tasks.
Amanda argues these agents remove handoff friction and can replace many go-to-market roles because they maintain memory and context across interactions.

ADVICE

Apply The Right Methodology To Each Buyer

Meet buyers where they are and apply the right sales methodology dynamically instead of forcing a single script.
OneMind aims to detect buyer intent and pick Challenger, solution selling, or a transactional path based on who the buyer is and their stage.

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Amanda Kahlow joins Revenue Builders to unpack what happens when AI stops assisting go-to-market teams and starts replacing entire functions. Drawing on her experience founding SixthSense and now leading 1mind, she explains how technology originally built for Alzheimer’s caregivers evolved into AI “superhumans” capable of running demos, qualifying buyers, building business cases, and onboarding customers. The conversation gets real about some of the uncomfortable questions facing sales today: what happens to SDRs, how the AE role changes, why traditional handoffs between Sales, Marketing, and Customer Success break down, and what “the final mile” of human selling really looks like. For revenue leaders, the bigger question isn’t whether AI will impact go-to-market… it’s how quickly org design, skill sets, and accountability models need to adapt.

Amanda Kahlow is the Founder and CEO of 1mind and the Founder of Sixth Sense. She is a multi time enterprise founder building AI systems designed to transform the full go-to-market lifecycle.

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Key takeaways from this episode:

00:00 – How tech built for Alzheimer’s caregivers evolved into AI that can qualify buyers, run demos, and move deals forward.
05:09 – What Amanda really means by a “superhuman”, and why it’s far beyond an AI SDR bolted onto your website.
06:27 – Why buyers are increasingly more comfortable with AI than humans in early-stage conversations, and what that does to traditional sales handoffs.
16:48 – How automated knowledge ingestion and system integrations are collapsing AI onboarding timelines from ~4 months to ~4 weeks.
30:23 – The GTM shakeup: SDRs disappear, AEs become strategic operators, and humans remain for one thing only… the “final mile.”
46:36 – The ultimate question: can AI replace high-cost revenue roles profitably? And what happens to trust, security, and data ownership in regulated industries?

Hosted by five-time CRO John McMahon and Force Management Co-Founder John Kaplan, the Revenue Builders podcast goes behind the scenes with the sales leaders who have been there, done that, and seen the results.

This show is brought to you by Force Management. We help companies improve sales performance, executing their growth strategy at the point of sale.

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