Siim Land Podcast #475 Q&A: Biggest things that contribute to my health, does caffeine age the brain, can you make up for lost sleep and more
Oct 18, 2025
Dive into the fascinating world of health insights, where the impact of exercise on inflammation is explored. Discover the intriguing research on melatonin megadosing and its gaps in clinical evidence. The podcast compares popular supplement brands and reveals the true value of Urolithin A. Caffeine's effects on brain aging are discussed, alongside sleep debt strategies that suggest catch-up sleep can help. Finally, learn about cultivating a healthy relationship with food that appreciates occasional indulgences.
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Take Saunas To Boost Recovery
- Use sauna after vigorous training to boost recovery, reduce inflammation, and lower respiratory infection risk.
- Regular sauna plus exercise can improve VO2 max and lower resting blood pressure more than exercise alone.
Be Cautious With Melatonin Megadoses
- Consider melatonin megadosing only experimentally and with caution because clinical trials are lacking.
- Siim Land has self-tested doses up to 10 mg and plans higher trials but notes evidence is limited.
Stacks Versus Individual Ingredients
- Supplement stacks differ: Blueprint and Novos are mixed formulas while DoNotAge sells single ingredients.
- NovosCore felt safer and simpler, Blueprint had one useful softgel, and DoNotAge offers high-quality individual options.