The Jesse Chappus Show 689: Methylene Blue, Fully Explained | Dr. Scott Sherr
18 snips
Jan 27, 2026 
Dr. Scott Sherr, a board-certified internist and hyperbaric/health optimization expert known for methylene blue research. He traces methylene blue’s history, explains how it supports mitochondria and performance, covers dosing, administration routes, safety concerns like MAOI effects, and practical product and timing tips. Short, practical guidance on when and how people might trial it.
AI Snips
Chapters
Transcript
Episode notes
Methylene Blue Targets Mitochondria
- Methylene blue concentrates in mitochondria and can both increase energy production and support detoxification.
- Low doses bypass dysfunctional complexes and recycle NAD, improving brain fog, pain, and inflammation.
Buy Pharmaceutical‑Grade Only
- Avoid buying fish-tank or random liquid methylene blue due to contamination and variable potency.
- Use pharmaceutical-grade products and test certificates of analysis or trusted suppliers.
Start Low, Titrate, Reserve High Doses Briefly
- Use low doses (about 4–25 mg) for mitochondrial support and titrate slowly over days.
- Reserve higher doses (≈50–150 mg) short‑term for infections and rebuild the microbiome afterwards.