The Curbsiders Internal Medicine Podcast

#101: Cirrhosis: Medications, decompensation, complications

11 snips
Jun 25, 2018
Ask episode
AI Snips
Chapters
Transcript
Episode notes
ADVICE

Protein Intake in Cirrhosis

  • Never prescribe low protein diets for cirrhosis patients, especially those with hepatic encephalopathy.
  • Cirrhosis is catabolic; patients need high protein to prevent muscle loss and worsen outcomes.
ADVICE

NASH Medications

  • Use Vitamin E for NASH in non-cirrhotic, non-diabetic patients.
  • Avoid Vitamin E in cirrhotic or diabetic patients; consider pioglitazone but be mindful of weight gain and other side effects.
INSIGHT

Circulatory Dysfunction in Cirrhosis

  • The circulatory dysfunction in cirrhosis is driven by splanchnic vasodilation and relative hypovolemia.
  • This triggers a vicious cycle of vasoconstriction, sodium/water retention, worsening portal hypertension, and ultimately, hepatorenal syndrome.
Get the Snipd Podcast app to discover more snips from this episode
Get the app