

The Curbsiders Internal Medicine Podcast
The Curbsiders Internal Medicine Podcast
The Curbsiders Internal Medicine Podcast brings you expert interviews, clinical pearls, and practice-changing knowledge — plus the occasional bad joke. Trusted by 100,000+ health professionals every month, we cover the full spectrum of internal medicine to keep you learning and laughing. No boring lectures here, just high-value content and a healthy dose of humor. Fantastic for Internal Medicine, Family Medicine, Primary Care, and Hospital Medicine.
Support the show:
patreon.com/curbsiders
Download our Primary Care Starter Guide e-book patreon.com/c/curbsiders/shop
Episodes
Mentioned books

58 snips
Mar 23, 2026 • 1h 31min
518: Cardiology Meets Longevity
Greg Katz MD, cardiologist and prevention expert at NYU focused on advanced lipidology and long-term risk reduction. He talks about when ApoB and Lp(a) change management. He explains how coronary calcium and CTA act as tiebreakers. He explores spotting early cardiometabolic risk and the role of wearables and CGMs.

22 snips
Mar 16, 2026 • 1h 6min
#517 DIGEST: Weight regain after weight loss medications, GLP1/GIP comparisons, valacyclovir for Alzheimer’s, and nudges to encourage deprescribing
A rapid review of GLP-1 and GIP therapies, emerging triple-agonists, and cardiovascular trial signals. A look at patterns of weight regain after stopping medication and counseling implications. A surprising trial where valacyclovir worsened cognition in early Alzheimer’s. Behavioral nudges to increase deprescribing and the practical tradeoffs of alerts and clinician burden.

74 snips
Mar 9, 2026 • 1h 34min
REBOOT: #481 Prediabetes and Diabetes Prevention with Dr. Scott Isaacs
Scott Isaacs MD, an endocrinologist and obesity medicine specialist at Emory and AACE president, walks through screening and spotting atypical prediabetes. He outlines which tests to use and pitfalls to watch for. He covers exam clues, lifestyle strategies, metformin and other meds, and how to combine therapies and follow patients over time.

20 snips
Mar 2, 2026 • 1h 19min
#516 Lyme Disease Primer featuring Dr. Sophie Woolston
Sophie Woolston, MD — infectious diseases physician and clinician-educator specializing in Lyme and cardiac infectious diseases. She walks through recognizing erythema migrans, stages of Lyme, and limits of serologic testing. Practical talk on treatment choices, tick removal and prevention, post-exposure doxycycline, and when to avoid prolonged antibiotics.

83 snips
Feb 23, 2026 • 1h 26min
#515 Primary Aldosteronism, A Deep Dive with Anand Vaidya, MD
Anand Vaidya, MD — endocrinologist and adrenal disorders expert at Mass General Brigham and Harvard Medical School. He explains what primary aldosteronism is and why it matters. He reviews who should be screened, practical renin/aldosterone testing strategies, pitfalls from medications and imaging, and evolving localization and treatment options including new imaging and therapies.

40 snips
Feb 16, 2026 • 1h 10min
#514 Hotcakes: Oral Semaglutide, Fish Oil in ESRD, IV Iron During Infection, New US Dietary Guidelines, & Anticoagulation after Ablation in AFib
Joshua Gilman, clinical cardiology commentator who reviews cardiovascular trials, joins to unpack recent high-impact studies. They cover oral semaglutide for weight loss and its tolerability, a striking fish oil trial in hemodialysis patients, IV iron given during infection and its methodological pitfalls, the new US Dietary Guidelines, and anticoagulation strategies after AF ablation.

45 snips
Feb 9, 2026 • 1h 32min
REBOOT: #469 Inpatient Heart Failure
Gurusher Panjrath, an advanced heart failure and transplant cardiologist who leads GWU’s Heart Failure and Mechanical Circulatory Support Program, walks through inpatient heart failure care. He covers POCUS and echo timing. Practical diuretic strategies and adjuncts. Starting SGLT2s and the four-pillars approach. Managing cardiogenic shock, right heart cath indications, and safe discharge planning.

31 snips
Feb 2, 2026 • 1h 24min
#513 Pituitary Incidentalomas
Dr. Maria Fleseriu, professor and pituitary specialist who directs a major Pituitary Center, walks through managing unexpected pituitary findings. She explains micro vs macro lesions, essential hormonal testing, and when imaging or surgery is needed. Practical advice on visual field testing, empty sella assessment, and follow-up strategies keeps clinicians confident and efficient.

59 snips
Jan 26, 2026 • 1h 32min
REBOOT: #462 Male Hypogonadism Pearls with Dr. Bradley Anawalt: Insights on Testosterone Deficiency
Bradley D. Anawalt MD, endocrinologist and Chief of Medicine with expertise in male reproductive health. He walks through practical approaches to low testosterone: who to test and how, why lifestyle and weight loss often trump therapy, nuances of lab interpretation, fertility-preserving options, and choosing and monitoring treatment while watching for hematocrit and sleep apnea risks.

175 snips
Jan 19, 2026 • 2h 12min
#512 Sleep Optimization and CBT for Insomnia with Ashley E. Mason, PhD
Dr. Ashley E. Mason, an associate professor of psychiatry at UCSF, shares her expertise on overcoming insomnia through cognitive behavioral therapy. She breaks down effective strategies like stimulus control and time-in-bed restriction. Learn how to optimize sleep hygiene, the impact of supplements and substances, and why consistent wake times are key. Dr. Mason also discusses the risks of sleep medications and the potential role of cooling bedding and proper wind-down routines. This informative discussion offers practical insights for better sleep.


