The Curbsiders Internal Medicine Podcast #140 Psychopharmacology 2.0 - Antidepressant Master Class
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Feb 18, 2019 Dr. Patrick Finley, a professor of clinical pharmacy at UCSF and expert in psychopharmacology, dives into the nuances of treating depression. He shares practical tips on switching antidepressants and managing withdrawal symptoms. They explore strategies for handling persistent depression and the complexities involved in antidepressant transitions, particularly during pregnancy. The discussion also touches on the role of genetic factors in medication response, emphasizing a tailored approach for patient care.
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Vacation Withdrawal
- Patients forgetting medication on vacation can experience withdrawal.
- This can lead to unnecessary ER visits due to unusual symptoms.
Pregnancy and Antidepressants
- When discussing antidepressants during pregnancy, assess psychiatric history and relapse likelihood.
- Review the evidence of SSRI safety during pregnancy, except for paroxetine.
Breastfeeding and SSRIs
- SSRIs are generally safe during breastfeeding, according to an AHRQ report.
- Most psychotropics enter breast milk due to their lipophilic nature.