Maintenance Phase

Fen Phen & Redux

17 snips
Oct 27, 2020
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INSIGHT

Local Cluster Sparked National Alarm

  • Clinicians in Fargo found an unexpectedly high cluster of PPH cases, implying a 2,300x increased risk from Fen-Phen/Redux.
  • Those local findings triggered broader investigations and major national media coverage.
INSIGHT

PR Denial Echoed Tobacco Playbook

  • Wyeth's PR downplayed risks by calling early evidence 'inconclusive' and comparing risk to lightning strikes.
  • These tactics mirror tobacco-industry denial strategies that exploit scientific uncertainty to delay action.
INSIGHT

Internal Memos Show Prior Knowledge

  • Trial discovery revealed Wyeth and Interneuron knew about safety problems before pushing approval and marketed misleading statistics.
  • Internal memos showed deliberate strategies to emphasize danger from obesity while downplaying drug harms.
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